86 research outputs found
1H-FID-MRSI LIVE DEMO @14.1T
No full text<p>Live demos of 1H-FID-MRSI- acquisitions at 14.1T by <a href="https://www.epfl.ch/labs/mrs4brain/">MRS4Brain research group</a> @ CIBM MRI EPFL AIT. Two live demos recorded directly on our 14.1T scanner containing the protocol used to acquired FID-MRSI data sets, including the imaging performed before the FID-MRSI acquisitions. The protocol used to acquired in vivo macromolecules with FID-MRSI is also presented in the video from 22/02/2024. Please open the videos with VLC media player.</p>
<p>Please cite the following article if you are using the protocol and sequence described herein</p>
<p><em>“Fast high-resolution metabolite mapping in the rat brain using 1 H-FID-MRSI at 14.1T” </em></p>
<p><em>Dunja Simicic, Brayan Alves, Jessie Mosso, Guillaume Briand, Thanh Phong Lê, Ruud B. van Heeswijk, Jana Starčuková, Bernard Lanz, Antoine Klauser, Bernhard Strasser, Wolfgang Bogner, Cristina Cudalbu</em></p>
<p><em>under review in NMR in Biomed</em></p>
DEMO_MRS4Brain_toolbox
No full text<p>Live demos of MRS4Brain toolbox used for 1H-FID- MRSI data processing. </p>
<p>The <em>MRS4Brain Toolbox</em> is developed by <a href="https://www.epfl.ch/labs/mrs4brain/">MRS4Brain research group</a> @ CIBM MRI EPFL AIT and was designed to offer advanced functionalities for Bruker preclinical MRSI data, encompassing preprocessing, fitting, quantification, semi-automatic quality control, co-registration and segmentation of metabolic maps using anatomical images, all conveniently integrated within a single open-source graphical user interface (GUI). The development of this user-friendly toolbox aims to streamline the processing workflow and enhance the accessibility of MRSI for researchers in the preclinical field. </p>
<p>MRS4Brain toolbox is available for download here: <a href="https://github.com/MRS4Brain/MRS4Brain-toolbox">MRS4Brain/MRS4Brain-toolbox (github.com)</a> and <span><a href="https://github.com/AlvBrayan/MRS4Brain-toolbox/">https://github.com/AlvBrayan/MRS4Brain-toolbox/</a></span></p>
<p>Please cite the following article if you are using MRS4Brain toolbox to process your data</p>
<p><em>“Fast high-resolution metabolite mapping in the rat brain using 1 H-FID-MRSI at 14.1T”</em></p>
<p><em>Dunja Simicic, Brayan Alves, Jessie Mosso, Guillaume Briand, Thanh Phong Lê, Ruud B. van Heeswijk, Jana Starčuková, Bernard Lanz, Antoine Klauser, Bernhard Strasser, Wolfgang Bogner, Cristina Cudalbu</em></p>
<p><em>under review in NMR in Biomed</em></p>
The Absence of Love Scenic
No full textLa ausencia del amor escénico trata sobre la experiencia personal que tuvo el estudiante Brayan Torres, autor de la tesis, sobre su montaje de grado, que se llamó "Inexpresable amor" dirigida por el Director Marcelo Islas en el año 2013, en la que argumenta que el sentimiento de amor nunca estuvo en escena, si no las consecuencias de este, como lo son los celos, la infidelidad y la ausencia. Ausencia que el toma para recrear su performance en esta obra.The absence of love stage is about the personal experience that the student Brayan Torres, author of the thesis, on mounting grade was that "Unspeakable Love" directed by the Director Marcelo Islands in 2013 was called, which argues the feeling of love was never staged, if not the consequences of this, such as jealousy, infidelity and absence. Absence that the decision to recreate their performance in this work
Perancangan Sistem Informasi Penyaluran Dana Bantuan Sosial Berbasis Web di Kantor Lurah Pulo Brayan Darat I
No full textThe process of distributing social assistance from sub-districts to date, especially in Pulo Brayan Darat 1 village, still uses manual. The Pulo Brayan Darat 1 Medan Timur Village Office faces several problems, including: the process of processing data on receipt of Social Assistance (BANSOS) takes a relatively long time. By designing a web-based Information System for the Distribution of Social Assistance Funds, it is hoped that it can increase efficiency, transparency and effectiveness in the distribution of social assistance funds, as well as providing real benefits for people in need. This research uses data to prepare social assistance funds. The method used is a qualitative method. Research Methodology. To obtain the data needed in this writing, the following research method was used: Field Research. This research was carried out directly in the field to obtain the necessary data. In this case, the author made direct observations regarding web-based social assistance fund distribution activities at the Pulo Brayan Darat sub-district office. 1. Library Research. The research was carried out based on literature or theoretical in nature, which was carried out by reading books and lecture materials related to this research. Interviews (Interviews) The author conducted direct interviews with the sub-district staff and employees at the Pulo Brayan Darat 1 sub-district office. The aim of this research in designing a web-based information system for the distribution of social assistance funds is to determine concrete steps to increase efficiency in the process of distributing social assistance funds so that they can achieve targets more quickly and precisely. Research methods and procedures that can reduce administrative errors in managing data on aid recipients, so that the information available is more accurate and reliable. The result of this research is to produce a web-based information system for distributing aid funds at the Pulo Brayan Darat 1 Village Head Office, the recording of social aid aid funds has been computerizedProses penyaluran bantuan sosial dari kecamatan hingga saat ini, khususnya di Kelurahan Pulo Brayan Darat 1, masih menggunakan cara manual. Kantor Kelurahan Pulo Brayan Darat 1 Medan Timur menghadapi beberapa permasalahan, antara lain: proses pengolahan data penerimaan Bantuan Sosial (BANSOS) membutuhkan waktu yang relatif lama. Dengan merancang Sistem Informasi Penyaluran Dana Bantuan Sosial berbasis web, diharapkan dapat meningkatkan efisiensi, transparansi, dan efektivitas dalam penyaluran dana bantuan sosial, serta memberikan manfaat yang nyata bagi masyarakat yang membutuhkan. Penelitian ini menggunakan data untuk penyusunan dana bantuan sosial. Metode yang digunakan adalah metode kualitatif. Metodologi Penelitian. Untuk memperoleh data yang dibutuhkan dalam penulisan ini, maka digunakan metode penelitian sebagai berikut: Penelitian Lapangan. Penelitian ini dilakukan secara langsung di lapangan untuk memperoleh data yang diperlukan. Dalam hal ini, penulis melakukan observasi langsung terkait kegiatan penyaluran dana bantuan sosial berbasis web di kantor kecamatan Pulo Brayan Darat. 1. Penelitian Kepustakaan.Penelitian ini dilakukan berdasarkan kepustakaan atau bersifat teoritis, yang dilakukan dengan cara membaca buku-buku dan bahan kuliah yang berhubungan dengan penelitian ini. Wawancara (Interview) Penulis melakukan wawancara langsung dengan pihak kecamatan dan pegawai di kantor kelurahan Pulo Brayan Darat 1. Tujuan penelitian ini dalam merancang sistem informasi penyaluran dana bantuan sosial berbasis web adalah untuk menentukan langkah-langkah konkrit guna meningkatkan efisiensi dalam proses penyaluran dana bantuan sosial agar dapat mencapai sasaran dengan lebih cepat dan tepat. Metode dan prosedur penelitian yang dapat mengurangi kesalahan administrasi dalam pengelolaan data penerima bantuan, sehingga informasi yang tersedia lebih akurat dan terpercaya. Hasil penelitian ini adalah menghasilkan sistem informasi penyaluran dana bantuan berbasis web di Kantor Kepala Desa Pulo Brayan Darat 1, pencatatan dana bantuan sosial sudah terkomputerisas
Sistem Informasi Pencatatan Waktu Kerja di PT.KAI (Persero) Balai Yasa Pulu Brayan Medan
No full textPT. Kereta Api Indonesia (Persero) a large company that was founded in 1945 which continues to strive to provide the best service. Balai Yasa Pulu Brayan as an inseparable part of PT. Kereta Api Indonesia (Persero), whose duty is to carry out maintenance of facilities especially locomotives are required to always produce the best care. Along with the changing times and the rapid progress in the field of technology, both in terms of facilities that must be treated and support treatment. The system method that the author uses in developing software to build this information system is a research method in the form of direct observation and collecting documents needed for making this application program, using modeling tools including context diagrams, Data Flow Diagrams (DPF). While database application development tools using Visual Basic 6.0 application programs. From the results of the development of the system above is expected to be able to overcome the weaknesses that have been felt
Fast high-resolution metabolite mapping in the rat brain using 1H-FID-MRSI at 14.1T
No full textMagnetic resonance spectroscopic imaging (MRSI) enables the simultaneous non-invasive acquisition of MR spectra from multiple spatial locations inside the brain. While 1H-MRSI is increasingly used in the human brain, it is not yet widely applied in the preclinical settings, mostly because of difficulties specifically related to very small nominal voxel size in the rodent brain and low concentration of brain metabolites, resulting in low signal-to-noise ratio SNR.
In this context, we implemented a free induction decay 1H-MRSI sequence (1H-FID-MRSI) in the rat brain at 14.1T. We combined the advantages of 1H-FID-MRSI with the ultra-high magnetic field to achieve higher SNR, coverage and spatial resolution in the rodent brain, and developed a custom dedicated processing pipeline with a graphical user interface: MRS4Brain toolbox.
LCModel fit, using the simulated metabolite basis-set and in-vivo measured MM, provided reliable fits for the data at acquisition delays of 1.3 and 0.94 ms. The resulting Cramér-Rao lower bounds were sufficiently low (<30%) for eight metabolites of interest, leading to highly reproducible metabolic maps. Similar spectral quality and metabolic maps were obtained between 1 and 2 averages, with slightly better contrast and brain coverage due to increased SNR in the latter case. Furthermore, the obtained metabolic maps were accurate enough to confirm the previously known brain regional distribution of some metabolites. The acquisitions proved high reproducibility over time.
We demonstrated that the increased SNR and spectral resolution at 14.1T can be translated into high spatial resolution in 1H-FID-MRSI of the rat brain in 13 minutes, using the sequence and processing pipeline described herein. High-resolution 1H-FID-MRSI at 14.1T provided reproducible and high-quality metabolic mapping of brain metabolites with significantly reduced technical limitations.Dunja Simicic and Brayan Alves are joint first author
Carta informando sobre el estado de las misiones de California, 1776 diciembre 25
No full textCarta informando sobre el estado de las misiones de California, específicamente las Misiones de San Diego, San Juan Capistrano y Santa Clara, y la fuerza militar según noticias que el autor ha recibido de correspondencia anterior. El autor señala la suspensión de la reconstrucción de la Misión de San Diego en ruinas después de la revuelta, recomendando clemencia para los líderes de la rebelión. El autor también solicita el establecimiento de la Misión Santa Clara cerca del Presidio de San Francisco, indicando los suministros necesarios para la fundación. —— Letter informing on the state of the California missions, specifically Missions San Diego, San Juan Capistrano, and Santa Clara, and the military force per news the author has received from prior correspondence. The author notes the suspension of the reconstruction of the ruined Mission of San Diego after the revolt, recommending clemency for the leaders of the rebellion. The author also requests the establishment of Mission Santa Clara near the Presidio of San Francisco, indicating the necessary supplies for the founding. 2 f. (4 p.
Noise-reduction techniques for 1H-FID-MRSI at 14.1T: Monte-Carlo validation & in vivo application
No full textProton magnetic resonance spectroscopic imaging (1H-MRSI) is a powerful tool
that enables the multidimensional non-invasive mapping of the neurochemical
profile at high-resolution over the entire brain. The constant demand for
higher spatial resolution in 1H-MRSI led to increased interest in
post-processing-based denoising methods aimed at reducing noise variance. The
aim of the present study was to implement two noise-reduction techniques, the
Marchenko-Pastur principal component analysis (MP-PCA) based denoising and the
low-rank total generalized variation (LR-TGV) reconstruction, and to test their
potential and impact on preclinical 14.1T fast in vivo 1H-FID-MRSI datasets.
Since there is no known ground truth for in vivo metabolite maps, additional
evaluations of the performance of both noise-reduction strategies were
conducted using Monte-Carlo simulations. Results showed that both denoising
techniques increased the apparent signal-to-noise ratio SNR while preserving
noise properties in each spectrum for both in vivo and Monte-Carlo datasets.
Relative metabolite concentrations were not significantly altered by either
methods and brain regional differences were preserved in both synthetic and in
vivo datasets. Increased precision of metabolite estimates was observed for the
two methods, with inconsistencies noted on lower concentrated metabolites. Our
study provided a framework on how to evaluate the performance of MP-PCA and
LR-TGV methods for preclinical 1H-FID MRSI data at 14.1T. While gains in
apparent SNR and precision were observed, concentration estimations ought to be
treated with care especially for low-concentrated metabolites.Comment: Brayan Alves and Dunja Simicic are joint first authors. Currently in
revision for NMR in Biomedicin
Análisis tecno-tipológico de la cerámica arqueológica Panzaleo: Un estudio de la cultura material alfarera depositada en el Museo de la Escuela Isidro Ayora del cantón Latacunga, provincia de Cotopaxi.
No full textThis work titling "Techno-typological analysis of Panzaleo archaeological ceramics: A study of the pottery material culture deposited in the Museum of the Isidro Ayora School of the Latacunga canton, Cotopaxi province" aims to apply a study systematic study that identifies cultural traits that describe the history of the aboriginal Panzaleo culture, considering the pottery works that have been found within the province and deposited in the museum of the Isidro Ayora School. In this perspective, descriptive and explanatory research has been used, with a qualitative methodology. At the time of establishing the methodology, the theoretical references that argue the case study were collected to apply the research methodology where pottery production is taken as a basis to describe the form, composition and iconography, thus revealing several historical biases of the culture that They were embodied in a clean way, such as customs, traditions, clothing, rituals, food and territory in which they were developed related to the different pottery productions. The conclusions denote that the Panzaleo culture reflected its history in the pottery productions according to the geographical location in which they moved, since the cultural material is a quality technology for the time in which they were developed, therefore, it is recommended that Archaeological studies are more detailed and technical in order to retrieve more information about our cultural legacy that allows educating the next generations of students about our past.El presente trabajo de titulación que lleva por nombre “ Análisis tecno-tipológico de la cerámica arqueológica Panzaleo: Un estudio de la cultura material alfarera depositada en el Museo de la Escuela Isidro Ayora del cantón Latacunga, provincia de Cotopaxi” tiene como objetivo aplicar un estudio sistemático que identifique rasgos culturales que describan la historia de la cultura aborigen Panzaleo, considerando los trabajos de alfarería que han sido encontrados dentro la provincia y depositados en el museo de la Escuela Isidro Ayora. En esta perspectiva, se ha empleado una investigación de tipo descriptiva y explicativa, con una metodología cualitativa. Al momento de establecer la metodología se recopilo los referentes teóricos que argumenten el caso de estudio para aplicar la metodología de la investigación donde se toma como base la producción alfarera para describir la forma, composición e iconografía, revelando así varios sesgos históricos de la cultura que estaban plasmados de forma explícita, como costumbres, tradiciones, vestimenta, rituales, alimentación y territorio en el que se desarrollaban relacionado a las distintas producciones alfareras. Las conclusiones denotan que la cultura Panzaleo reflejaba su historia en las producciones alfareras de acuerdo a la localidad geográfica en la que se desplazaban ya que el material cultural es un tecnificado de calidad para la época en que se desarrollaban, por lo tanto, se recomienda que los estudios arqueológicos sean más minuciosos y tecnificados con la finalidad de que se pueda rescatar más información de nuestro legado cultural que permita educar a las siguientes generaciones de estudiantes sobre nuestra pasado.UNACH, Ecuado
Escudriñando el tiempo: ¿El tlacuache como Cihuateteo?
No full textTesis para obtener el grado de Licenciatura en Etnohistori
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