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Data for Rotterman et al., MODULATION OF CENTRAL SYNAPSE REMODELLING AFTER REMOTE PERIPHERAL INJURIES BY THE CCL2-CCR2 AXIS AND MICROGLIA
No full textThis excel file contains the raw data of figures in the following paper
MODULATION OF CENTRAL SYNAPSE REMODELLING AFTER REMOTE PERIPHERAL INJURIES BY THE CCL2-CCR2 AXIS AND MICROGLIA
Travis M. Rotterman, Zoë Haley-Johnson, Tana S. Pottorf, Tavishi Chopra, Ethan Chang, Shannon Zhang, William M. McCallum, Sarah Fisher, Haley Franklin, Myriam Alvarez, Timothy C. Cope, Francisco J. Alvarez
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2. Stephanion. Homenaje a Maria C. Giner., édité par C. Cordoner, M. P. Fernanda Alvarez, J.A. Fernadez Delgado
No full textDobias-Lalou Catherine. 2. Stephanion. Homenaje a Maria C. Giner., édité par C. Cordoner, M. P. Fernanda Alvarez, J.A. Fernadez Delgado. In: Revue des Études Grecques, tome 104, fascicule 497-499, Juillet-décembre 1991. p. 595
2. Stephanion. Homenaje a Maria C. Giner., édité par C. Cordoner, M. P. Fernanda Alvarez, J.A. Fernadez Delgado
No full textDobias-Lalou Catherine. 2. Stephanion. Homenaje a Maria C. Giner., édité par C. Cordoner, M. P. Fernanda Alvarez, J.A. Fernadez Delgado. In: Revue des Études Grecques, tome 104, fascicule 497-499, Juillet-décembre 1991. p. 595
Transfected aequorin in the measurement of cytosolic Ca2+ concentration ([Ca2+]c). A critical evaluation.
No full textTargeted recombinant aequorins represent to date the most specific means of monitoring [Ca2+] in subcellular organelles (Rizzuto, R., Simpson, A. W. M., Brini, M., and Pozzan, T. (1992) Nature 358, 325-328; Brini, M., Murgia, M., Pasti, L., Picard, D., Pozzan, T., and Rizzuto, R. (1993) EMBO J. 12, 4813-4819; Kendall, J. M., Dormer, R. L., and Campbell, A. K. (1992) Biochem. Biophys. Res. Commun. 189, 1008-1016). Up until now, however, only limited attention has been paid to the use of recombinant photoproteins for measuring, in mammalian cells, the [Ca2+] in the cytoplasm, a compartment for which effective Ca2+ probes are already available. Here we describe this approach in detail, highlighting the advantages, under various experimental conditions, of using recombinant cytosolic aequorin (cytAEQ) instead of classical fluorescent indicators. We demonstrate that cytAEQ is expressed recombinantly at high levels in transiently transfected cell lines and primary cultures as well as in stably transfected clones, and we describe a simple algorithm for converting aequorin luminescence data into [Ca2+] values. We show that although fluorescent indicators at the usual intracellular concentrations (50-100 microM) are associated with a significant buffering of the [Ca2+]c transients, this problem is negligible with recombinantly expressed aequorin. The large dynamic range of the photoprotein also allows an accurate estimate of the large [Ca2+]c increases that are observed in some cell types such as neurons. Finally, cytAEQ appears to be an invaluable tool for measuring [Ca2+]c in cotransfection experiments. In particular, we show that when cotransfected with an alpha 1-adrenergic receptor (coupled to inositol 1,4,5-trisphosphate generation), cytAEQ faithfully monitors the subpopulation of cells expressing the receptor, whereas the signal of fura-2, at the population level, is dominated largely by that of the untransfected cells
Arom, S. et Thomas, J. M. C, Les Mimbo, génies du piégeage et le monde surnaturel des Ngbaka- Ma'bo (République centrafricaine).
No full textAlvarez-Péreyre Frank. Arom, S. et Thomas, J. M. C, Les Mimbo, génies du piégeage et le monde surnaturel des Ngbaka- Ma'bo (République centrafricaine).. In: Journal de la Société des Africanistes, 1975, tome 45, fascicule 1-2. pp. 219-220
Arom, S. et Thomas, J. M. C, Les Mimbo, génies du piégeage et le monde surnaturel des Ngbaka- Ma'bo (République centrafricaine).
No full textAlvarez-Péreyre Frank. Arom, S. et Thomas, J. M. C, Les Mimbo, génies du piégeage et le monde surnaturel des Ngbaka- Ma'bo (République centrafricaine).. In: Journal de la Société des Africanistes, 1975, tome 45, fascicule 1-2. pp. 219-220
The influence of summer upwelling at the western boundary of the Cantabrian coast
No full textPrego, R., Varela, M., DeCastro, M., Ospina-Alvarez, N., García-Soto, C., & Gómez-Gesteira, M. (2012). The influence of summer upwelling at the western boundary of the Cantabrian coast. Estuarine, Coastal and Shelf Science, 98, 138–144. doi:http://dx.doi.org/10.1016/j.ecss.2011.12.00
Do newborns detect prosodic violations in an unfamiliar language at birth?
No full text: Experience with language starts prenatally, as the intrauterine environment allows speech prosody to get through. Martinez-Alvarez and colleagues (2023) demonstrated that newborns detect utterance-level prosodic violations in the language they heard prenatally, French. It remains unknown, however, whether this discrimination ability requires prenatal experience with a given language or whether newborns have an early sensitivity to the shapes of prosodic contours that extends beyond prenatal experience. To this purpose, we tested infants exposed prenatally to Italian with the French stimuli of Martinez-Alvarez et al. (2023), and we measured their brain responses with fNIRS. We found that Italian-exposed newborns discriminate between standard and deviant prosodic contours in French, activating right hemispheric areas specialized for the processing of prosody in adults. However, the time course and the localization of the effect were different from those found in French newborns. This suggests that an early sensitivity to prosodic contours may be modulated by prenatal experience at birth
Heatwaves during embryonic development reveal duration-dependent effects in zebrafish
No full textHeatwaves, defined as periods of unusually high temperatures are increasingly frequent due to climate change. It is well known that ectotherms are particularly vulnerable to heat stress, especially during sensitive life stages such as embryonic development. However, the consequences of short, ecologically relevant heat stress, remain less investigated. Here, we investigate the effects of short-term heat stress during embryonic development in zebrafish (Danio rerio). For this, 1753 embryos were exposed to simulated heatwaves of different durations (6, 24, or 48 h) and frequencies (one or two events) during development, with a temperature of 35 °C (+7 °C above the standard temperature of 28 °C). Their pre- and post-natal survival, hatching time, larval body size, and locomotor activity once hatched were evaluated. Additionally, the larval locomotor activity was assessed at control and heat-stress temperatures to determine if embryonic heat stress would result in larvae coping better with high temperatures. Our results showed that exposure to high temperatures (35 °C) increased pre-natal mortality, and further effects varied depending on the duration of the heatwave. Longer heatwaves (48 h) accelerated the rate of development but resulted in smaller larvae that swam more under heat stress, while short heatwaves (24 h and two repeated periods of 6 h) did not have any effect. Our results indicate that the embryonic stage is highly sensitive to even brief periods of heat stress, such as those experienced during a heatwave, and that the duration of exposure leads to different responses. These findings offer crucial insights into the extreme sensitivity of embryos to heatwaves and highlight wider consequences for individuals and populations, which are crucial for predicting how species will respond to ongoing climate change
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