1,721,075 research outputs found
Physiological parameters predicting the outcome of surgical and nonsurgical treatment of fecal incontinence
No full textFecal incontinence is a multifactorial disease. Anorectal physiology studies play an outstanding role in the evaluation of its etiology and severity, the two main factors that constitute the basis for the correct choice of treatment. However, the prognostic role of clinical factors and anorectal physiological tests in predicting the outcome to either conservative or surgical treatment is questionable. © 2007 Springer-Verlag Italia
Cutting-Edge Research Trends in Colorectal Disease
No full text: The scientific effort in improving colorectal disease treatment and outcomes has allowed for a continuous shift of burdens that were previously thought to be unassailable [...]
The role of food contamination by mycotoxins in human diseases: A review
No full textDirect or indirect (by animals) contamination of food by mycotoxins produced by fungi is very common and should be considered a major problem in this era of globalization because it can severely affect human health and sometimes produce cancer. Some of the mycotoxins are well known and widely studied, but many others have not been evaluated yet for their potential toxicity. In this study we review the best-known human diseases induced by the most common mycotoxins such as aflatoxin B1, ochratoxin A, fumonisins and zearalenone and their mechanism of action. © SINPE-GASAPE
Prevention of anovaginal fistula during double-stapling of ileal pouch-anal anastomosis
No full textRecto- or anovaginal fistula is a troublesome complication of double-stapling technique in ultralow rectal anastomosis for rectal cancer or in ileal pouch-anal anastomosis for ulcerative colitis. In this study, a technique for preventing this problem by means of separation of the vaginal wall during the stapler firing is described using a flexible spatula introduced through the rectovaginal septum into the peritoneal cavity
An overview
No full textConclusions: The main problem in assessing anal function in patients with a neoanal sphincter, particularly those after total anorectal reconstruction following Miles' operation, is the onset of defecatory disturbance, which can sometimes be even more troublesome than anal incontinence. No QoL questionnaires have yet been drawn up for patients with obstructed defecation or combined functional disorders. There is a strong need for such a tool, which would make it possible to perform a better evaluation of the results of these newer operations and to compare different groups of patients undergoing different anal neosphincter procedures. © 2005 Springer-Verlag London Limited
Constipation after hysterectomy: fact or fiction?
No full textHysterectomy is responsible for numerous postoperative complications largely urological, but sometimes of sexual or colorectal function. The latter involve modifications of bowel function resulting in constipation as a result of delayed transit, infrequent evacuations and greater difficulty in expelling faeces. We have reviewed the topic, and consider the various hypotheses whereby these modifications may result from hormonal alterations, iatrogenic causes, or variations in recto-bladder sensitivity. Any of these could justify the modifications in bowel function detected in these patients. The studies carried out so far provide no clear information about the type of constipation that develops after hysterectomy, as we lack prospective studies that compare bowel function before and after operations. Nor is it clear whether we are dealing with constipation as a result of delayed transit or obstructed defaecation, nor which pathogenetic mechanisms are involved. In view of the large number of hysterectomies that are done, sometimes prophylactically, controlled prospective studies are warranted to address these issues more fully
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