38 research outputs found

    Fluoride and dental caries

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    Fluorine was probably discovered by the chemist Scheele in 1771, and eventually isolated in 1886 by Moissan. Its presence in bones and teeth was initially disputed but eventually confirmed in the middle of the eighteenth century. In this article the author discusses the few epidemiological studies which confirm the relationship between fluoride concentration in drinking water, mottled enamel and the incidence of dental caries and also describes the Maltese scene in regards the caries level in tap water.peer-reviewe

    Electrophilic aromatic acylation

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    Applied Science

    The proper use of artefacts: A philosophical theory of the social constitution of artefact functions

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    Artefacts are humanly designed objects with a function. Their proper function is what they are for. This book develops a theory of these functions on the basis of the idea that artefacts are used in a social context. Current theories of artefact functions are inadequate to deal with this special character. Functions of artefacts are defined partly in the traditional way, referring to their physical nature and causal history, but an additional constitutive feature is introduced and analysed in detail: the social context in the form of the institutionalisation of use. Func-tions can be partly defined in terms of institutionalised use. This analysis provides the basis for the understanding of artefact use and the evaluation of artefact use. Then further consequences for understanding artefacts and their functions are investi-gated and developed. In the first place it is shown how this view of functions helps understand a little investigated aspect of the communication of artefact functions, namely by way of the artefacts structural aspects. The artefact is, as it were, the carrier of symbolic meaning con-cerning its own proper function. For this analysis the pragmatic approach to language and linguistic communication is applied and extended to cover the case of function communica-tion. In the second place, the normative notion of proper function is used to give an action theoretic account of artefact use, enabling us to understand and evaluate it. The plan account of intentional action is invoked, which enables the proper use of artefacts to be analysed in terms of a use plan of the artefact. This shows how the social features of the proper function are actual part of an agents reasons for using an artefact in a particular way. Thus, the more standard accounts of action in terms of rationality and rational reconstructions can be com-bined with the social features constituting artefact functions. The analysis of artefact functions thus provides the material for a thorough analysis of artefact use.Technology, Policy and Managemen

    Neutrophilic eccrine hidradenitis secondary to pegfilgrastim in a patient with synovial sarcoma

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    A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author's publication fees in this Open Access journal. The Open Access Fund, administered by librarians from the KU, KU Law, and KUMC libraries, is made possible by contributions from the offices of KU Provost, KU Vice Chancellor for Research & Graduate Studies, and KUMC Vice Chancellor for Research. For more information about the Open Access Fund, please see http://library.kumc.edu/authors-fund.xml.Key Clinical Message Here, we report a case of neutrophilic eccrine hidradenitis (NEH) in a teenage male with synovial sarcoma associated with extracutaneous manifestations including myositis and splenomegaly secondary to pegfilgrastim. To the best of our knowledge, NEH has not been previously reported to occur in association with extracutaneous manifestations

    Een beeld van een kust: Inspiratie voor de Kustnota

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    De kust als spiegel / Maurits Groen De levende kust / Govert D. Geldof Integraal beleid : te kust en te keur? / Gerrit Hagelstein en Philip Idenburg De nieuwe kusten van Noordzee en IJsselmeer / Wouter van Dieren De kust als menselijke gradiënt / Reinier Jan Scheele Duinen in een levende kust / Helias Udo de Haas Het verlangen naar de kust : de kust als toeristisch-recreatief domein / Theo Beckers De kust over 25 jaar : een normatief gezichtspunt / Karel Soudijn Een beeld van kust / Anne van der Meidenkustnot

    Developing a parametric script for the preliminary design and optimization of concrete balanced cantilever bridges

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    In this thesis, research is performed into parametric design of balanced cantilever bridges within the total road design. The main research question is: What can be achieved by using a parametric model in the preliminary design phase, with the possibility to optimize and compare concrete bridges on material usage, costs and environmental impact? And to answer this question, the cantilever bridge and all other elements in the road design are investigated and a parametric model is developed. In this model the total vertical alignment of the road design is implemented along with approach bridges, substructure and foundations. Furthermore, the results of the designs are visualized in a 3D environment compared with an overview of the material costs and environmental impact. In the "Discussion", the following is concluded: Although the parametric model for the preliminary design of concrete cantilever bridges took a long time to develop, this time investment can be regained by using the model several times. Because by using the parametric model for the preliminary design of concrete bridges, the design time per procurement is decreased significantly. Furthermore, the design process of the balanced cantilever bridge has become more flexible since changes are automatically implemented for the whole model. Also the chance for (human) errors is decreased, for instance the risk of data loss is minimized due to the model’s single environment. Since only a limited amount of calculations is performed by the model, the results of the analysis must be used with caution. Another advantage is the instant results as produced by the model. These results consist of a visualization of the design and an overview of the material amounts, with their costs and environmental impact. Furthermore, the model is also able to optimize these results in a fast way due to a smart evolutionary solver. This all together makes the parametric model a useful tool with high potential, but it should be furtherdeveloped and improved.Civil Engineerin

    Onderzoek naar het hydraulisch functioneren van een uasb reactor

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    In dit rapport is het resultaat weergegeven van het onderzoek naar het hydraulische funktioneren van UASB (Upflow Anaerobic Sludge Blanket) reactoren. Met name gaat het om het stromingspatroon bij de openingen aan de onderzijde van de bezinkruimte. Tijdens de biochemische reacties in de reactor ontstaan gasbellen, die bij het opstijgen, aanleiding geven tot een ongunstige vloeistofstroming aan de onderzijde van de bezinkruimte. Door deze vloeistofstroming onstaan hogere intreesnelheden in de bezinkruimte. Dit heeft tot gevolg dat door de instroming een zekere mate van turbulentie in de bezinkruimte (het bovenste deel van de reactor) onststaat. Omdat het procestechnisch noodzakelijk is om een goede bezinking van het slib te bewerkstelligen in de bezinkruimte, zal een vloeistofstroming gecreëerd moeten worden die een geringe turbulentie veroorzaakt in de bezinkruimte.Hydraulic EngineeringCivil Engineering and Geoscience

    TriAna: An image triangulation visualization and analysis tool

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    At the University of Chile, prof. dr. N. Hitschfeld Kahler is conducting research on the automatic generation of meshes in both 2D- and 3D-environments based on images or 3D-models. At the moment she is researching the analysis of images of tree stems by generating 2D meshes of triangles (triangulations) over the image and retrieving data based on these triangulations and the image, for example the amount of tree rings and specific data about the climate in the region from where the tree originated. The analyses performed using this method could be faster than performing them using traditional pixel calculations. However, the current tools that are available for research are inadequate in three aspects. First of all, they're simplistic, non-intuitive tools that aren't designed for useful interaction but only create a single, simple output. They lack any kind of advanced functionality that could help speed up the research. Secondly, the program has little extendability and reusability, meaning it's difficult to improve the functionality and to modify it for different research within the same domain. And lastly, the triangulation algorithm and tools were produced as research for the Integrated Systems Laboratory (IIS), ETH Z who retain ownership of them. This means that prof. N. Hitschfeld Kahler currently doesn't have the required permissions to continue her research with the current tools. Our job was to create a visual tool which solved the previously mentioned weaknesses and which would enable an easy way to integrate a new triangulation algorithm and implement new tools to analyse the triangulations in conjunction with the images. We've named the program 'triAna', 'short for triangulation analysis . This report will discuss the process and results of our project. First we'll give a progress report of the entire project. The analysis of the requirements and the design of triAna will be discussed in the consequent chapters. The implementation and its problems and solutions will be discussed thereafter.Electrical Engineering, Mathematics and Computer Scienc
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