53 research outputs found
Enhancing Data Integrity with Machine Learning Algorithms in Clinical Trials
No full textEnhancing Data Integrity with Machine Learning Algorithms
in Clinical Trial
Syed Mohammad Ali, Development, Poverty and Power in Pakistan: The impact of state and donor interventions on farmers
No full text
Syed Mohammad Ali, Development, Poverty and Power in Pakistan: The impact of state and donor interventions on farmers.
No full textBook Revie
Fiscal Decentralisation and the Performance of Health Sector in Kabale District, Uganda.
No full textThe study was to establish the impact of Fiscal Decentralization on health service delivery in Kabale District. This was based on the objectives namely; to identify the contribution of fiscal decentralization on health service delivery in Kabale district, to establish the factors that affect fiscal decentralization on health service delivery in Kabale District, to find out the solutions on challenges facing fiscal decentralization on the health service delivery in Kabale district. The study used exploratory and descriptive research design which involves analysis and the use of words because it enabled the researcher to draw valid and dependable conclusion and recommendations. The design of the study was built on a causal relationship based on the results from some of the data collection tools which are questionnaires, oral interviews and observations of the researcher. The study used questionnaire, interviewing and documentary review that gave the researcher the inner understanding of the study. Those methods that helped the researcher to collect data from the field of study.196 respondents were selected for the study whereby, 84 were male and 112 were females. From the findings most respondents agreed on factors that influence fiscal decentralisation on health service delivery; such as supportive supervision, sensitization, administrative and management systems, revenue collection and administration. Findings indicate that fiscal decentralization can improve the efficiency of public service delivery but only under specific conditions. First, the decentralization process requires adequate political and institutional environments. Second, a sufficient degree of expenditure decentralization seems necessary to obtain favorable outcomes. Third, decentralization of expenditure needs to be accompanied by sufficient fiscal decentralization of revenue. Absent of those conditions, fiscal decentralization cannot be delivered. It was recommended that the government takes steps stem the fragmentation's in health service delivery in the country, provide the needed funding for health service delivery and in the medium to long term, detach the Department of Ministry of Health and create an all new Ministry to encompass and allied agencies in the country, Government must increase more funds in budgeting for the Ministry of Health, MOH should mobilize all health agents to solve problems and challenges facing health sector, MOH should renovate all health buildings, put up more health facilities, improve on transport system, and increase the number of doctors.Kabale Universit
Internet-based Cognitive Behavioral Therapy for Tinnitus: Insights from Health Care Professionals
No full textInternet and Pornography Use During the COVID-19 Pandemic: Presumed Impact and What Can Be Done
No full textThe COVID-19 pandemic continues to cause an immense psychosocial strain worldwide. Excessive use of the internet during these psychologically trying times, fueled by physical isolation as a result of lockdowns, has translated into dysfunctional behaviors. A growing body of evidence suggests an unprecedented increase in internet use and consumption of online pornography during the pandemic, and possibly even directly caused by it. In this review, the authors report data from relevant sources to show the rise in pornography use during lockdowns in different countries worldwide. In addition to a brief overview of the neurobiology of internet addiction broadly and problematic online pornography use specifically, similarities with substance use disorders are explained. Further, the current status of the debate about defining diagnostic criteria is discussed. Finally, the review sheds light on the potential detrimental outcomes during the future post-pandemic "re-adaptation," while simultaneously offering preventative and management strategies for harm reduction. The authors conclude that foresightedness with utilizing existing tools and therapies and exercising appropriate amounts of caution could go a long way in addressing the challenges that lie ahead in the post-pandemic era
Role and Perspectives of Inflammation and C-Reactive Protein (CRP) in Psychosis: An Economic and Widespread Tool for Assessing the Disease
No full textSchizophrenia is a major psychotic disorder affecting nearly 23.6 million people globally and greatly impacting the cognitive and social functioning of individuals. Multiple risk factors, including genetic, environmental, and epigenetic factors have been identified. However, the exact mechanism by which some factors aid in the development of schizophrenia is still uncertain. Acute and/or long-standing inflammation has been implicated as both a cause and effect of schizophrenia. Heightened immune responses have been documented in large cohorts of individuals with schizophrenia. While not completely known, multiple hypotheses, such as disruption of the blood–brain barrier, alterations in the kynurenine/tryptophan pathway, and increased microglial activation, have been presented to correlate inflammation with schizophrenic symptoms. Measurement of C-reactive protein (CRP) is a commonly performed and inexpensive test on patients’ serum to determine levels of systemic inflammation in the body. Multiple studies have reported an elevated CRP level in different stages of schizophrenia, indicating its potential to be used as a viable biomarker in the diagnosis and monitoring of schizophrenia along with assessing treatment response to conventional and non-conventional treatment regimens. This review aims to evaluate the role of inflammation, in general, and CRP, in particular, in the pathogenesis of schizophrenia and its potential significance in diagnostic, therapeutic, and preventative approaches towards schizophrenia and psychosis
Parental separation and parental mental health in childhood and tinnitus and hyperacusis disability in adulthood: a retrospective exploratory analysis
No full textObjectives: To explore the relationships between parental separation and parental mental health in childhood with tinnitus and hyperacusis disability in adulthood. Design: Retrospective cross-sectional. Study sample: The data for consecutive patients who attended a tinnitus and hyperacusis clinic in the UK over a six months period were included (n = 184). Results: 14.7% of patients reported that while they were growing up, their parents were separated or divorced. There were no significant differences in Tinnitus Handicap Inventory (THI) and Hyperacusis Questionnaire (HQ) between patients with and without history of parental separation. About 40.2% reported history of mental health disorders in their parents. The scores on THI and HQ were worse in the group that reported mental health disorders in their parents (p < .01). Parental mental health illness did not significantly relate to THI, however, it was significantly related to the risk of hyperacusis (odds ratio [OR], after adjusting for age and gender: 2.05, p = .026). The adjusted OR for a subgroup of patients with a diagnosis of hyperacusis was 6.7 (p = .011), indicating a stronger relationship for this subgroup. Conclusions: Among patients seeking help for their tinnitus and hyperacusis, poor parental mental health was associated with increased hyperacusis disability
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