581 research outputs found
sj-docx-1-cat-10.1177_10760296221107889 - Supplemental material for COVID-19 Infection in Patients with Comorbidities: Clinical and Immunological Insight
Supplemental material, sj-docx-1-cat-10.1177_10760296221107889 for COVID-19 Infection in Patients with Comorbidities: Clinical and Immunological Insight by Omnia El-Badawy, Nahla M. Elsherbiny, Doaa Abdeltawab, Doaa M. Magdy, Lamees M. Bakkar, Shimaa A. Hassan, Elham A. Hassan, Ahmed M. Thabet, Ahmed M. Ashmawy, Ehab F. Moustafa, Wael A. Abbas, Ahmad Bahieldeen Ahmad, Amal Rayan, Khaled Saad, Amira Elhoufey, Hosni A. M. Hussein, Ali A. Thabet and Asmaa M. Zahran in Clinical and Applied Thrombosis/Hemostasis</p
Colors 2017
CONTENTS
Dearest Uncle, Abigail Dolan 7;
I Remember, Abigail Dolan 8;
Woman of the Corn, Ali Everts 9;
Zombies at Night, Ali Everts 12;
Imaginary, Audrey Walker 13;
Shroud, Bennet Long 15;
An Ode to My Memories, Brett Charlton 15;
Unplucked, Brett Charlton 17;
Egg, Cassandra Offt 18;
Playing at the World, Cassandra Offt 20;
Daisy Petals, Cassie Drinkall 30;
Ryan Gosling: An Ode to the Bathroom Stall, Connor Hague 31;
Blood and Mascara, Connor Smith 34;
Contracts with God, Doaa Mohaisen 43;
The Bullet, Doaa Mohaisen 48;
Turning 20, Doaa Mohaisen 51;
1939, Valerie Do 54;
Neptune, Valerie Do 55;
Fred, Isabella Geraghty 56;
Under the Big Sky, Kristina McGee 57;
Time Never Stops, Kristina McGee 57;
"I Cry at the End of Titanic" and Other Lies, Meghan Fellows 59;
Follow Me, Meghan Fellows 61;
Ghost Cat, Rhiannon Sturgess 71;
Losing, Rhiannon Sturgess 72;
Ben and Jerry’s, Samantha Reed 72;
Both Eyes Open, Samantha Reed 89;
Solitude, Sarina Crews 92;
If My Heart Was a Candle, Tommy Le 94;
A Reasonable Price, Virginia Reeves 95;
Su Corazon, William French 99
Effect of Aggregate Type and Specimen Configuration on Concrete Compressive Strength
A Master of Science thesis in Civil Engineering by Doaa Mansour entitled, "Effect of Aggregate Type and Specimen Configuration on Concrete Compressive Strength," submitted in April 2017. Thesis advisor is Dr. Sherif Yehia. Soft and hard copy available.Cement content, water-to-cement ratio (w/c), aggregate size and type, specimen size and shape, loading rate, and curing are some factors that affect the concrete compressive strength. This study focuses on the effect of aggregate type and specimen configuration on the compressive strength of concrete. Six concrete mixes utilizing 10 mm and 20 mm natural, LAYTAG and Pumice lightweight, and recycled aggregate from two sources, "Bee'ah and Jabal Ali", were used to investigate the effect of these two factors. In addition, samples from ready-mix concrete producers with different strengths "C45, C75, C60, and C80" were evaluated for the compressive strength using standard size cylinders and cubes. Strength development was monitored on the 7th, 28th, and 90th day. In addition, flexural strength, split tension, and modulus of elasticity were evaluated on the 28th and 90th day. Statistical analyses were conducted to estimate the relationships among the variables considered in the investigation. Moreover, other mechanical properties as a function of compressive strength were discussed and compared to those predicated by the ACI specification. Results indicate that standard specimen size has a negligible effect on the concrete compressive strength; whereas, specimen shape had a noticeable effect on the compressive strength as the Cylinder/Cube ratio on the 90th day was ranging between 0.781 and 0.929. The concrete compressive strength and modulus of elasticity were significantly affected by the aggregate type. Other mechanical properties, such as flexural strength and split tensile strength, were less affected by the aggregate type which was also confirmed by the values predicted with the ACI equations.College of EngineeringDepartment of Civil EngineeringMaster of Science in Civil Engineering (MSCE
Synthesis and mechanistic studies into the cytotoxic activity of garlic-related trisulfides in cancer cells
Garlic has long been recognized for its medicinal properties and is well-documented to produce organosulfur compounds (OSCs) with significant chemopreventive and therapeutic potential. Among these, trisulfides are notable phytochemicals that exhibit a broad range of biological activities, including anticancer effects both in vitro and in vivo, as well as antimicrobial, antioxidant, and antithrombotic properties. Recent methodologies have enabled the development of novel synthetic methodologies for synthesizing unsymmetrical organotrisulfides. This thesis explores our contributions to the synthesis of these compounds, their cytotoxicity and their mechanisms of action against cancer cells. Building on our group's previous research on the cytotoxicity of ajoene, which demonstrated its ability to modify proteins by S-thioallylation of cysteine residues through a thiol-disulfide exchange reaction, we extend these findings to trisulfides, providing new insights into their potential as anticancer agents. Chapter One offers an overview of naturally occurring trisulfides, highlighting their significant biological activities. It emphasizes trisulfides from natural sources, particularly diallyl trisulfide (DATS), a garlic-derived compound with notable anticancer potential. This chapter sets the stage for exploring trisulfides therapeutic potential in cancer treatment, a central theme of this dissertation. Chapter Two reviews existing synthetic methods for trisulfide formation, highlighting the need for greener and more sustainable approaches. It discusses current challenges, including the difficulty of synthesizing unsymmetrical trisulfides, and introduces our novel method for achieving these compounds with high yield, purity, and selectivity. This chapter lays the groundwork for the synthetic developments detailed in chapter 4. Chapter Three shifts the focus to the cancer biology of organosulfur compounds (OSCs), with a detailed examination of trisulfides. It provides an in-depth analysis of their extraction, biosynthesis, metabolism, and bioavailability, particularly in relation to cancer chemoprevention. The chapter investigates the role of reactive species, including hydrogen sulfide (H₂S) and perthiols (RSSH), generated through thiolysis exchange of trisulfides with protein thiols. The role of H₂S as a crucial gaseous signaling molecule is examined, highlighting its involvement in various physiological processes. The chapter also explores perthiols, Page | IV characterized by their unique chemical properties, which enable them to participate in redox reactions and radical processes. Chapter Four presents our novel methodology for synthesizing unsymmetrical trisulfides, including details of the optimization conditions and the stability of the products. The methodology yields aliphatic trisulfides in high yield and purity, while aromatic trisulfides are more labile. The trisulfide's distinct chemical shifts in 1H NMR allow for their identification and differentiation from other sulfur species. The applicability of this method extends to a range of functional groups, including those derived from cysteine and sugar moieties. Chapter Five investigates the cytotoxic effects of trisulfides in cancer cells, focusing on a refined library of trisulfides to identify structure-activity relationships, particularly in benzyl derivatives. The chapter examines the impact of various substituents on perthiol stability, demonstrating that electron-donating groups prolong perthiol lifetime and enhance cytotoxicity. This by raising their pKa and reducing their disproportionation to homotrisulfides. The p-OMe derivative, in particular, displayed higher extracellular perthiol concentrations, as measured by Ellman's assay, corroborating initial stability studies. The chapter further extends to monitoring H₂S production in WHCO1 cancer cells using a fluorescent probe, establishing that fluorescence intensity, indicative of H₂S concentration, increases with greater electron release from para-substituents. This relationship between enhanced perthiol stability and increased H₂S production reinforces the thiolysis-based mechanism of trisulfide cytotoxicity and suggests a pathway for designing more effective anticancer agents. Additionally, studies using a dansyl-propyl trisulfide probe indicated localisation in the endoplasmic reticulum (ER), suggesting a role for the unfolded protein response (UPR) in conjunction with H₂S signaling in promoting apoptosis
Lifestyle Pattern of Visually Impaired Students at Special Blind Schools in Damanhour City
<p><strong>Abstract:</strong> Background: people with visual impairment are vulnerable because they are limited in access information and loss of vision can cause changes personal<sup>’</sup>s lifestyle. Aim: is to assess lifestyle pattern of visually impaired students at special blind schools in Damanhour city. Design: a descriptive cross-sectional research design. Settings: The Special Blind Schools in Damanhour city (namely El-Noor for the blind). Subjects: all visually impaired and blind students at the previous mentioned setting were included into the study (110 students). Tools: Tool (I): Students’ Profile Structural Interview Questionnaire. Tool (II): Students’ Healthy Behaviors and Lifestyle knowledge Assessment Sheet. Tool (III): Health Promoting Lifestyle Profile (HPLP) II. Results: the mean age of the studied students was 11.76 ± 3.706 years. The majority of them had poor level of knowledge compared to 65.4% of them had moderate health promoting lifestyle profile. There was highly statistically significant relation between students<sup>’</sup> total level of knowledge score regarding level of their health promoting lifestyle profile. Conclusion: the majority of visually impaired students had poor level of knowledge about healthy lifestyle. Recommendations: Providing visually impaired students with a booklet written in Braille that contains the most important daily healthy lifestyle habits.</p>
<p><strong>Keywords:</strong> Visual impairment, Lifestyle, Pattern, Students.</p>
<p><strong>Title:</strong> Lifestyle Pattern of Visually Impaired Students at Special Blind Schools in Damanhour City</p>
<p><strong>Author:</strong> Amina Mohamed Gomaa Hawash, Reem Bassiouny Mahmoud EL-Lassy<sub>, </sub>Doaa Ali El Demerdash</p>
<p><strong>International Journal of Novel Research in Healthcare and Nursing</strong></p>
<p><strong>ISSN 2394-7330</strong></p>
<p><strong>Vol. 10, Issue 3, September 2023 - December 2023</strong></p>
<p><strong>Page No: 84-100</strong></p>
<p><strong>Novelty Journals</strong></p>
<p><strong>Website: www.noveltyjournals.com</strong></p>
<p><strong>Published Date: 02-October-2023</strong></p>
<p><strong>DOI: <a href="https://doi.org/10.5281/zenodo.8398663">https://doi.org/10.5281/zenodo.8398663</a></strong></p>
<p><strong>Paper Download Link (Source)</strong></p>
<p><strong><a href="https://www.noveltyjournals.com/upload/paper/Lifestyle%20Pattern%20of%20Visually%20Impaired-02102023-3.pdf">https://www.noveltyjournals.com/upload/paper/Lifestyle%20Pattern%20of%20Visually%20Impaired-02102023-3.pdf</a></strong></p>International Journal of Novel Research in Healthcare and Nursing, ISSN 2394-7330, Novelty Journals, Website: www.noveltyjournals.co
QUALITY OF PRIMARY HEALTH CARE SERVICES IN FAMILY HEALTH CENTERS IN EL-BEHIRA GOVERNORATE
Abstract: High–quality primary health care services are the outcome of strong service delivery and the result of well-organized and achieved services, supported by a strong system and sufficient inputs, such as human resources, infrastructure, drugs, and supplies. The aim of the study is to assess the quality of PHC services in family health centers in El-Behira Governorate. Material and Methods: Research design: Descriptive research design will be used to conduct this study. Setting: The study will be conducted in governmental family health centers in El-Behira governorate affiliated with the Ministry of Health. Subjects: The subjects of the present study will be all the nurses (347) working in studied family health centers. Sampling: A multistage sampling technique will be used to select the required sample. Tools: two tools were used. Tool (I): Nurses' quality knowledge and perspective structured questionnaire sheet. Tool (Π): Quality of Primary Health Care Services Evaluation. Results: the vast majority of the nurses in Damanhour, Etay EL-Baroad, Abo-Homos were females. More than two thirds (68.6%) of the nurses in Damanhour FHC compared to less than two thirds of the nurses in Etay El-Baroad and Abo-Homos (66.4% and 64.3% respectively) and half (54.3%) of them in El-Rahmanya had a secondary school of nursing diploma. Among nurses with low perspectives, 3.2% of them had poor knowledge about quality compared to none of those with high perspectives. The Family Health Centers had the highest process mean score related to provision of services especially for maternity care, family planning services and childcare. While the total clinics' process is unsatisfactory for essential drugs. Conclusion: Based on the findings of the present study, it can be concluded that none of the studied family health centers in all districts studied had a high total quality level. A significant relation was found between nurses’ mean score of knowledge and their perspective levels related to quality of services and socio-demographic characteristics related to previous training and frequency of training. The Family Health Centers had the highest process mean score related to provision of services especially for maternity care, family planning services and childcare. Recommendations: The predominant policy recommendation is that the Egyptian Ministry of Health needs to improve the budget allocation for primary health care units and centers as it is the entrance keeper to secondary and tertiary health care. It is equally important to maintain the support policy for primary health care services in order to meet the restricted affordability of low-income people who would fight to get health care if the prices of examination and medication would be increased.
Keywords: primary health care, family health centers, quality of PHC services.
Title: QUALITY OF PRIMARY HEALTH CARE SERVICES IN FAMILY HEALTH CENTERS IN EL-BEHIRA GOVERNORATE
Author: Hend Salah Shehata, Enas Mohamed Ibrahim, Reem Bassiouny El Lassy, Doaa Ali Eldemrdash
International Journal of Novel Research in Healthcare and Nursing
ISSN 2394-7330
Vol. 10, Issue 1, January 2023 - April 2023
Page No: 154-170
Novelty Journals
Website: www.noveltyjournals.com
Published Date: 26-April-2023
DOI: https://doi.org/10.5281/zenodo.7868181
Paper Download Link (Source)
https://www.noveltyjournals.com/upload/paper/QUALITY%20OF%20PRIMARY%20HEALTH-26042023-2.pdfInternational Journal of Novel Research in Healthcare and Nursing, ISSN 2394-7330, Novelty Journals, Website: www.noveltyjournals.co
Utilization of Palm Wastes for Production of Invert Sugar
AbstractAn economically attractive technique was adopted using date palm fibers as a new carrier for invertase adsorption and for invert sugar production. Experiments were carried out to evaluate the results of incubation of Baker's yeast with palm fibers in aqueous solution at 40° C for half an hour. CO2 produced from this reaction was employed as a reactant and it succeeded to modify the cellulosic surface of the palm fibers. This increased the capacity of invertase that had been secreted from Baker's yeast to be immobilized tightly on the cellulosic surface of the fibers. These results confirmed by FTIR and SEM. Characterization of the enzyme indicated that 1 gram of immobilized invertase on such wastes can produce 600mg of invert sugar. By this technique, Egypt would be able to supply 6 million kg invert sugar per year. Molasses used instead of sucrose to assess the sustainability of the process
Public Policy Development and Implementation in the United Arab Emirates. A study of organizational learning during policy development and implementation in the Abu Dhabi Police and the United Arab Emirates Ministry of Interior
This reflective analysis of the Emirati public policy process (PPP) cycle and implications of uneven application of new public management (NPM) paradigms in the UAE offers insight into the way that public administrations develop, learn, evolve, and cope with new challenges during the policy development process. The author also assesses the relationship between organizational learning and organizational practices, to generate practical knowledge and experience that is translated into recommendations that will benefit UAE government organizations, and indeed any public sector organization in the Gulf Region.
Inside action research was chosen to emphasize the author's dual role as both a researcher and a participant. As an advisor to both the Ministry of the Interior (MOI) of the UAE and the Abu Dhabi Police (ADP), the author helped both organisations improve their PPP experiences while researching the challenges, learning, and adaptations which occurred while policy was being developed within the MOI. The author generated data through reflective memos, informal interviews, and document analysis, and presents her findings in terms of both academic findings and practice-oriented recommendations.
The author primarily found that new models were necessary to reflect the highly flexible and authority-oriented UAE PPP cycle. The author also explored how cultural understandings led to challenges with NPM and learning in the UAE public administration, hindering policy development. Finally, the author found that her own position, as a female expatriate in the Emirati government, allowed for some valuable reflection about experience of serving in a Global South public administration
CNN Technique Security Inspection for Data Computing Networks
The hypothetical as well as system derivation have been shaped by data computing into the analysis of tomorrow. The global computing framework is rapidly influencing cloud development. The security aspects in a cloud-based computing environment remain at the middle of attention, despite the fact that it is important to take further period for could investigation by motivating it to separate fields. The development of cloud subordinate divisions and expert centers has resulted in the provision of optional mission design that is subject to cloud advancement. In order to guard against the potential consequences of being exposed to undesirable communal contests in cases such that, the cloud servers it is adjusted to store such data, weak info of various parameters is typically stored in servers using wireless locations with the presence of various cloud-based systems using geographically consumed info networks producers. The flexibility and benefits of cloud computing will be difficult to accept if the security is inadequate. This study examines cloud analyzing and cloud structure while also addressing security concerns and information computing standards. In addition, a new adversaries administration security strategy based on CNN will be proposed and compared to other readily available security regions. The obtained results for the CNN algorithm show a success rate of 100% with only 0.18 losses at batch number of 2*104. Also the confusion matrix show a very high classification measure for the trained samples among the target with resulting classes
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