1,036 research outputs found

    Multicomponent image segmentation using a genetic algorithm and artificial neural network

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    Image segmentation is an essential process for image analysis. Several methods were developed to segment multicomponent images, and the success of these methods depends on several factors including 1) the characteristics of the acquired image and 2) the percentage of imperfections in the process of image acquisition. The majority of these methods require a priori knowledge, which is difficult to obtain. Furthermore, they assume the existence of models that can estimate its parameters and fit to the given data. However, such a parametric approach is not robust, and its performance is severely affected by the correctness of the utilized parametric model. In this letter, a new multicomponent image segmentation method is developed using a nonparametric unsupervised artificial neural network called Kohonen's self-organizing map (SOM) and hybrid genetic algorithm (HGA). SOM is used to detect the main features that are present in the image; then, HGA is used to cluster the image into homogeneous regions without any a priori knowledge. Experiments that are performed on different satellite images confirm the efficiency and robustness of the SOM-HGA method compared to the Iterative Self-Organizing DATA analysis technique (ISODATA). © 2007 IEEE.ARIA EH, 2004, P 20 ISPRS C IST TUR, P117; AWAD M, IN PRESS INT J REMOT; BACAO F, 2005, P ICCS 2005 C, P476; Baker J. E., 1987, P 2 INT C GEN ALG, P14; CHEN Q, 2004, LECT NOTES COMPUT SC, V33, P621; Chun DN, 1996, PATTERN RECOGN, V29, P1195, DOI 10.1016-0031-3203(95)00148-4; Fauzi M., 2003, P BRIT MACH VIS C, P519; HOLLLAND J, 1975, ADAPT NATURAL ARTIFI; HUAPT R, 2004, PRACTICAL GENETIC AL; Jensen J. R., 1996, INTRO DIGITAL IMAGE; Kohavi R., 1998, APPL MACHINE LEARNIN, V30, P271; Levine M. D., 1985, VISION MAN MACHINE; NEVATIA R, 1980, COMPUT VISION GRAPH, V13, P257, DOI 10.1016-0146-664X(80)90049-0; Ng SC, 1996, IEEE SIGNAL PROC MAG, V13, P38, DOI 10.1109-79.543974; PARZEN E, 1962, ANN MATH STAT, V33, P1065, DOI 10.1214-aoms-1177704472; PERKINS S, 2000, FUZZY SYST EVOL COMP, V3, P52; Pina P, 2003, INT GEOSCI REMOTE SE, P3516; PRATT W, 1991, DIGITA IMAGE PROCESS; Tou J.T., 1974, PATTERN RECOGNITION; Wang X., 2004, P IEEE C ROB AUT MEC, P991; Xiaoying Jin, 2003, Proceedings of the 12th IEEE International Conference on Fuzzy Systems (Cat. No.03CH37442); Xu BG, 2002, AATCC REV, V2, P42; Yao KC, 2000, PATTERN RECOGN, V33, P1575, DOI 10.1016-S0031-3203(99)00135-1; YIN HJ, 1995, NEURAL COMPUT, V7, P1178, DOI 10.1162-neco.1995.7.6.117834232

    The impact of COVID-19 on pharmacy education in Saudi Arabia

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    Abstract: In late 2019, the first COVID-19 case was announced. Subsequently, numerous other instances were found all around the world. On March 2, 2020, the first case was reported in Saudi Arabia. The Saudi government has taken several precautions to stop the spread of this pandemic sickness. Closing public and private schools and universities and moving educational activity to online platforms were two of these approaches. whether they are the 21 public pharmacy schools in Saudi Arabia or the. These abrupt transitions had an impact on 8 people, and depending on their level of preparedness, they responded differently. Here, we discuss the elements of the pharmacy school curriculum, including classroom instruction, laboratory work, and experiential learning, based on our experience at King Saud University. Keywords: Pharmacy education COVID-19 Assessment Lesson learned. Title: The impact of COVID-19 on pharmacy education in Saudi Arabia Author: Yasir Awad Ahmed, Bander kammash alshammari, Faisal Abdulrahman Al Amri, Turki Shafaq Alotaibi, Mazen Alawi Nubayri, Jamelah Ali Alshehri, Noha Ali M Alshehri International Journal of Life Sciences Research ISSN 2348-313X (Print), ISSN 2348-3148 (online) Vol. 10, Issue 3, July 2022 - September 2022 Page No: 89-93 Research Publish Journals Website: www.researchpublish.com Published Date: 26-September-2022 DOI: https://doi.org/10.5281/zenodo.7113029 Paper Download Link (Source) https://www.researchpublish.com/papers/the-impact-of-covid-19-on-pharmacy-education-in-saudi-arabiaInternational Journal of Life Sciences Research, ISSN 2348-313X (Print), ISSN 2348-3148 (online), Research Publish Journals, Website: www.researchpublish.co

    Switching to the Inflation Targeting Regime: Does it necessary for the case of Egypt?

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    The purpose of this paper is to answer the question of whether the switching to the Inflation Targeting (IT) regime is necessary for the Egyptian case or not? Our judgment of applying IT regime in the Egyptian economy is established on doubled criterion. That is, the practical experience of the inflation targeters, and the efficiency of Monetary Targeting Regime (MTR) in the case of Egypt. Defining the efficiency of a monetary policy regime by the efficiency of the embedded nominal anchor to send the right message to all practitioners about the potential behavior of the price level, I assessed the efficiency of MTR in Egypt by measuring; whether there is a relationship between money and prices, the stability of the velocity of circulation, and the stability of the demand for money function. The study concluded that MTR is not efficient to tie down individuals expectations about the future path of inflation in Egypt. Taking into account that IT regime is a way to reform monetary policy and it does not worsen economic performance it becomes necessary for Egypt to switch to the IT regime once the prerequisites for IT regime have been met.inflation targeting; demand for money function; monetary policy in Egypt.

    Modern Arabic literary biography : a study of character portrayal in the works of Egyptian biographers of the first half of the twentieth century, with special reference to literary biography

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    In Chapter one, I presented a comparative definition of the meaning of Sirah (PI.Siyar), Tarjamah (Pl. Tarajim), Manaqib, Tabaqat and Maghazi as they were understood in antiquity. I also showed how the meaning of Sirah in modern times has only narrowly developed. Although the method of biographical writing continuously developed in Europe, it hardly progressed in Modem Arabic Literature. The only exception was seen in the writings by the pioneers of enlightenment in Egypt at the beginning of the twentieth century. This change of direction relied on borrowing European methodology in biographical writing. In chapter two, I reviewed the early attempts at writing biographies in the nineteenth century by Abd al Rahman al- Jabarti and Ali Mubarak. Although both were the first pioneers in this respect, yet they followed the footpath of classical approach above all that of al-Maqarizi from whom -Ali Mubarak derived inspiration in his book Al-Khitat al-Tawfiqiyyah. In chapter three, I studied the twentieth century, starting with traditional biography writers who could not employ European methodologies and whose writings oscillated between biographical notes and biographical sketches; or whose texts were more of a literary study than a biography proper. In chapters four to nine, I selected the most renowned, productive writers who best represented methodologies of biography writing. Perhaps certain writers have not been mentioned in this period of study. This is not out of negligence but simply because their texts were totally out of reach, or their writings did not exhibit the required literary criteria. All methodologies representing the theory of biography writing in Egypt have been analysed in these chapters. All, in fact, form a digestion or assimilation of French,English and German schools. In Egypt, Taha Husayn is considered the chairman of the French school, al-Mazini and al-Aqqad of the English/German schools, al-Nuwaihi of the psychoanalytical/anatomical school and Sidqi who employed both. By contrast, al Iryan was the trailblazer of the distinguished biographical novel. In these chapters, I tried to lay out the general outlines these writers have produced in the production of biographical texts, and how these attempts were a successful step on the road of presenting literary biographies characterized by high world standards. Chapter ten may well seem traditional, but it is important to give a comparative outlook on the views of biography writers themselves when they study and analyse the same character. Among the characters studied ,I selected Bashsliar, Abu Nuwas, Ibn al-Run-i, al-Mutanabbi and al-Maarri. These are outstanding landmarks in the history of Arab verse and the subject of a multitude of studies as well. Modern biographers took these figures as a test field for the deployment and employment of biographical methodologies. I selected these examples to provide comparisons and explain how far these biographies were successful in producing a biography or a profile of those classical poets. The conclusion and the bibliographical list arrived at the end of research. I wish, however, to clarify one important point here. It seems that I could not fix the year 1950 as the temporal parameter of my research but took some textswhich were published shortly beyond that point. The reason for this obvious extension was either to give additional useful details or simply because chapters of such texts had already been published prior to that year and were known to the readership. At times I would satisfy myself with analysing the part rather than the whole. This again was meant to eschew repetition or was due to the fact that the book in question was not available

    Superconducting properties of zinc substitution in Tl-2223 phase

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    The effect of partial replacement of copper by zinc in Tl2Ba2Ca2Cu3O10-δ superconductor phase is studied. Superconducting samples of the nominal composition Tl2Ba2Ca2Cu3-xZnx O10-δ with x ranging from 0 to 0.6 are prepared under normal pressure by a one step of solid-state reaction technique. The samples are characterized by using X-ray powder diffraction, scanning electron microscope (SEM) and EDX. The X-ray data indicate that the partial replacement of Cu2+ions by Zn2+ions does not influence the tetragonal structure of the samples, and the lattice parameters a and c vary according to the difference in the ionic radii of Cu and Zn. The superconducting parameters, such as superconducting transition temperature Tc, critical current density Jc and irreversibility field Bir are calculated from electrical resistivity and AC-magnetic susceptibility measurements. © 2007 Elsevier B.V. All rights reserved.Abou-Aly A.I., 2002, INT C RES TRENDS SCI, V91; ADACHI S, 1990, PHYSICA C, V111, P543; Awad R, 2000, PHYSICA C, V341, P685, DOI 10.1016-S0921-4534(00)00650-X; Awad R, 2007, SUPERCOND SCI TECH, V20, P401, DOI 10.1088-0953-2048-20-4-017; Awad R, 2001, PHYSICA B, V307, P72, DOI 10.1016-S0921-4526(01)00971-1; Batista-Leyva AJ, 2003, SUPERCOND SCI TECH, V16, P857, DOI 10.1088-0953-2048-16-8-305; BEAN CP, 1964, REV MOD PHYS, V36, P31, DOI 10.1103-RevModPhys.36.31; BERKLEY DD, 1993, PHYS REV B, V47, P5524, DOI 10.1103-PhysRevB.47.5524; CHEN DX, 1990, PHYSICA C, V167, P317, DOI 10.1016-0921-4534(90)90349-J; Chu SY, 2000, PHYSICA C, V337, P229, DOI 10.1016-S0921-4534(00)00107-6; Fradina IA, 1999, PHYSICA C, V311, P81, DOI 10.1016-S0921-4534(98)00563-2; Glowacki BA, 1997, CRYOGENICS, V37, P609, DOI 10.1016-S0011-2275(97)00053-2; HAZEN RM, 1988, PHYS REV LETT, V60, P1657, DOI 10.1103-PhysRevLett.60.1657; Isber S, 2005, SUPERCOND SCI TECH, V18, P311, DOI 10.1088-0953-2048-18-3-018; Isber S, 2006, J PHYS CONF SER, V43, P450, DOI 10.1088-1742-6596-43-1-112; Kayed TS, 2003, CRYST RES TECHNOL, V38, P946, DOI 10.1002-crat.200310118; Kuhberger M, 2003, PHYSICA C, V390, P263, DOI 10.1016-S0921-4534(03)00706-8; LEE MW, 1995, PHYSICA C, V245, P6, DOI 10.1016-0921-4534(95)00100-X; Mezzetti E, 2000, PHYSICA C, V332, P115, DOI 10.1016-S0921-4534(00)00008-3; MOHAMMED NH, 2005, ARAB INT C REC ADV P, P9; Nishida A, 2003, PHYSICA C, V392, P349, DOI 10.1016-S0921-4534(03)00848-7; Pavard S, 1999, PHYSICA C, V316, P198, DOI 10.1016-S0921-4534(99)00259-2; Ravi S, 2000, PHYSICA C, V330, P58, DOI 10.1016-S0921-4534(99)00611-5; REN ZF, 1991, PHYSICA C, V184, P24, DOI 10.1016-0921-4534(91)91496-Q; RUCKENSTEIN E, 1989, MATER LETT, V8, P421, DOI 10.1016-0167-577X(89)90065-7; Tang H, 1997, PHYSICA C, V282, P2111, DOI 10.1016-S0921-4534(97)01171-4; Triscone G, 1996, PHYSICA C, V264, P233, DOI 10.1016-0921-4534(96)00262-6; VANDERAH TA, 1992, CHEM SUPERCONDUCTOR, P90; WANG YB, 1993, J LOW TEMP PHYS, V15, P169; WESTERHOLT K, 1989, PHYS REV B, V39, P11680, DOI 10.1103-PhysRevB.39.11680; Wisniewski A, 2000, PHYS REV B, V61, P791, DOI 10.1103-PhysRevB.61.791; XU YW, 1990, PHYSICA C, V169, P205, DOI 10.1016-0921-4534(90)90177-G; Yamauchi H, 1998, SUPERCOND SCI TECH, V11, P1006, DOI 10.1088-0953-2048-11-10-022; Yang Li, 1994, Physics Letters A, V18543

    The political economy of crisis in the Sudan 1973-1985

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    This thesis examines the political economy of the Sudan to reveal the nature and causes of the 1973-85 particular crisis in that country. The 1973-85 crisis is placed within the historical context of recurrent crises which have characterised the independent Sudan. It is argued that political and economic crises have occurred over the period 1956-1985 and several common features of these crises can be identified to constitute general political and economic trends. In their turn, they have characterized the general crisis since independence in 1956. The general crisis facing the Sudan is an organic crisis of transformation. Twenty nine years have elapsed between the Sudan becoming independent and 1985, the end of the period under study. The problems of transforming the inherited colonial economy and structures have remained on the national agenda since then, without resolution. The study of the colonial political and economic legacy provided an important component of the thesis as it reflected on the process of the articulation of the capitalist mode of production and the pre-capitalist modes of production which had prevailed in the country before the re-conquest of the Sudan in 1898. Political, institutional and market interrelationship affected the nature of the Sudanese economy, class structure and class struggle. The nature of the colonial state as an authoritarian and relatively autonomous state left its features in the political economy of the country. In trying to understand the crisis both in its particular and general manifestations the thesis examines the nature of the post-colonial state and its historical development. The colonial heritage of the country and the concrete class struggle gave the post-colonial state its nature and constituted its crisis. In revealing the nature of the post-colonial state a ruling power bloc is identified. That power bloc was composed of the religious and tribal aristocracy, the bourgeoisie and the military and civilian bureaucracy. The thesis argues that the crisis of the post-colonial state is a crisis of hegemony. The failure of the dominant power bloc, a fraction or a class of it to establish its hegemony is the main cause of the crisis of the state and the particular form of that crisis: the military civilian governments alterance in power. The post-colonial state's ability to use coercion was legitimately limited and its tendency towards authoritarianism was challenged by the urban democratic movement and the effective regional forces, especiallyt he Southern Sudanese. The politics of ethnic conflicts were closely related to the composition of the ruling power bloc as Northern, and of Arab Islamic culture. It was in the politics of ethnic conflicts that coercion was widely used against the Southern people. The civil war which struck the country twice contributed to the crisis of the post-colonial state. The essence of crisis of the economy is found in the crisis of agricultural production both in its irrigated and rain-fed sub-sectors. Though the nature of the crisis in both sectors is found in the process of articulation of capitalist and pre-capitalist modes, the result of the articulation process is different in both sub-sectors. Within this context the particular 1973-85 crisis is studied. The particular crisis is a continuation of the general post-colonial-crisis, yet distinguishable. The military bureaucratic fraction of the new petty bourgeoisie which dominated the state during the 1973-1985 period failed to establish its hegemony and ruled the country through an authoritarian state. The failure to build an alliance with the urban democratic movement in the North between 1969 and the July 1971 coup d'etat was a turning point in the history of the Nimeiri regime. The National Reconciliation of 1977 did not reach its logical conclusion by widening the base of the regime. The promulgation of Islamic Sharia Law in 1983 did not promote the regime's quest for legitimacy and remained to be an additional tool of repression. The study of the economic crisis of 1973-85 revealed that it was a continuation of the general crisis, as well as a particular crisis of simple and extended reproduction that resulted from specific policies of the regime. The regime failed to transform the structure of the economy. Despite the expansion, the economy remained unevenly developed, export-oriented, with weak inter-sector and inter-regional linkages; liable to be severely affected by intemational crises and moderately benefiting from international booms

    Ordinal optimization for dynamic network reconfiguration

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    Motivated by the challenge of efficiently reconfiguring distribution networks for power loss reduction, this study presents an approach for finding a minimum loss radial configuration for a power network using ordinal optimization. Ordinal optimization relies on order comparison and goal softening to make the problem solution easier and the computation more efficient. The successful application of ordinal optimization to such a complex optimization problem required the investigation of several algorithmic parameters. The solution algorithm was implemented in a software package, where an acceptable solution is considered good enough if it is in the top mpercent of the solutions with a probability P. Testing it on 33- and 136-bus systems, minimal power loss results were obtained on the 33-bus system that are in the top 0.03percent of the search space. Comparing the experimental results with other recently published methods showed the effectiveness of ordinal optimization for minimum loss calculations and motivated further studies in smart-grid-like scenarios, where the results obtained for different load levels were in the top 0.13percent of the search space. © 2011 Copyright Taylor and Francis Group, LLC.Abdelaziz A. Y., 2009, IEEE POW EN SOC M CA; Abdelaziz AY, 2010, ELECTR POW SYST RES, V80, P943, DOI 10.1016-j.epsr.2010.01.001; Baran M. E., 1989, IEEE T POWER DELIVER, V4, P101; Braverman M., 2007, 22 ANN IEEE C COMP C, P225; BUNCH JB, 1982, IEEE T POWER AP SYST, V101, P284, DOI 10.1109-TPAS.1982.317104; Carreno EM, 2008, IEEE T POWER SYST, V23, P1542, DOI 10.1109-TPWRS.2008.2002178; CASTRO CA, 1990, ELECTR POW SYST RES, V19, P137, DOI 10.1016-0378-7796(90)90064-A; CHIANG HD, 1990, IEEE T POWER DELIVER, V5, P1568, DOI 10.1109-61.58002; CIVANLAR S, 1988, IEEE T POWER DELIVER, V3, P1217, DOI 10.1109-61.193906; Debs A. S., 1987, MODERN POWER SYSTEM, P180; de Oliveira LW, 2010, INT J ELEC POWER, V32, P840, DOI 10.1016-j.ijepes.2010.01.030; Dogrusoz U., 1994, INT C COMP INF APR, V6, P46; Fusheng Li, 2009, P 6 ANN IEEE COMM SO, P1, DOI 10.1109-ICUT.2009.5405702; GOSWAMI SK, 1992, IEEE T POWER DELIVER, V7, P1484, DOI 10.1109-61.141868; Ho Y. C., 1992, DISCRETE EVENT DYN S, V2, P61, DOI 10.1007-BF01797280; Ho Y. C., 1994, P 33 IEEE C DEC CONT, V2, P1470; Ho Y.C., 2007, ORDINAL OPTIMIZATION, P7; Kachem M. A., 2000, ELECT POWER ENERGY S, V22, P269; Kashem MA, 1999, IEE P-GENER TRANSM D, V146, P563, DOI 10.1049-ip-gtd:19990694; Lau TWE, 1997, J OPTIMIZ THEORY APP, V93, P455, DOI 10.1023-A:1022614327007; Mantovani JRS, 2000, SBA CONTROLE AUTOMAC, V11, P150; MAYEDA W, 1965, IEEE T CIRCUITS SYST, VCT12, P181; Merlin A, 1975, P 5 POW SYST COMP C, P1; Morton AB, 2000, IEEE T POWER DELIVER, V15, P996, DOI 10.1109-61.871365; NARA K, 1992, IEEE T POWER SYST, V7, P1044, DOI 10.1109-59.207317; Ravibabu P, 2008, IEEE Region 8 International Conference on Computational Technologies in Electrical and Electronics Engineering. SIBIRCON 2008, DOI 10.1109-SIBIRCON.2008.4602603; SHERMAN J, 1950, ANN MATH STAT, V21, P124, DOI 10.1214-aoms-1177729893; SHIRMOHAMMADI D, 1989, IEEE T POWER DELIVER, V4, P1492, DOI 10.1109-61.25637; Sivanagaraju S, 2006, ELECTR POW COMPO SYS, V34, P249, DOI 10.1080-15325000500240854; Sivanagaraju S, 2008, ELECTR POW COMPO SYS, V36, P513, DOI 10.1080-15325000701735389; Swarnkar A, 2011, ELECTR POW SYST RES, V81, P1619, DOI 10.1016-j.epsr.2011.03.020; Yu Y., 2002, IEEE T POWER SYST, V3, P172953

    Erratum: Statistical analysis on the radiological assessment and geochemical studies of granite rocks in the north of Um Taghir area, Eastern Desert, Egypt (Open Chem. (2022) 20: 1 (254–256) DOI: 10.1515/chem-2022-0131)

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    Corrigendum to: Awad H, Abu El-Leil I, Nastavkin A, Tolba A, Kamel M, El-Wardany R, et al. Statistical analysis on the radiological assessment and geochemical studies of granite rocks in the north of Um Taghir area, Eastern Desert, Egypt. Open Chem. 2022;20(1):254 6. https://doi.org/10.1515/chem-2022-0131. After publishing the article, the authors noticed that there is a mistake in the authors contributions section. It was given as: Author contributions: H.A., I.A., A.N.conception of the study; A.T, M.K.experiment; R.E., A.R.analysis and manuscript preparation; H.Z., H.A., H.T.data analysis and writing the manuscript; S.I., H.Z.analysis with constructive discussions. It should be given as: Author contributions: H.A., I.A., A.N.conception of the study; A.T, M.K.experiment; R.E., A.R.analysis and manuscript preparation; H.Z., H.A., H.T.data analysis and writing the manuscript; H.A., A.E., S.I., H.Z.analysis with constructive discussions. © 2022 De Gruyter. All rights reserved

    OCCUPATIONAL BURNOUT AMONG NURSES WORKING IN MATERNAL AND CHILD HEALTH CENTERS IN EL BEHEIRA GOVERNORATE

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    Abstract: Nurses who are working in maternal and child health care setting suffer from excessive load that makes them more liable for occupational burnout because their work involves many preventive and curative health services that are provided to both women and under-five children. The study aimed to: assess the level of occupational burnout among nurses working in Maternal and Child Health centers (MCH) in El Beheira Governorate. Design: a descriptive study was utilized to meet the aim of this study. Setting: The study was conducted in 9 MCH centers within 5 directorates out of 16 directorates present in El Beheira Governorate including Damanhour, Kafer El dawar, Abo Elmatamer, Etay Elbarod and Shobarqet directorates. These directorates have the greatest number of nurses within MCH centers. Subjects: composed of 300 nursing staff who are working at previously mentioned setting. Tools: two tools were used for data collection; Nurses’ characteristics self –administrated sheet and The Maslach Burnout Inventory (MBI). Results: around two third of the studied nurses had high level of emotional exhaustion, and the majority of them had high level of high depersonalization and personal accomplishment. Moreover, there was a statistically significant negative correlation between emotional exhaustion and personal accomplishment domain and positive correlation between emotional exhaustion and depersonalization. On the other hand, there was no statistically significant correlation between personal accomplishment and depersonalization. Conclusion: based on the results of the present study it can be concluded that, although the current study subjects had high level of emotional exhaustion and depersonalization, they still had high level of personal accomplishment. Moreover, emotional exhaustion was negatively correlated with personal accomplishment and positively correlated with depersonalization. On the other hand, there was no statistically significant correlation between personal accomplishment and depersonalization. Recommendation: frequent workshops about effective coping strategies to be used during time of stress need to be implemented for nurses to protect against occurrence of burnout. Keywords: nursing staff, occupational burnout, maternal and child health center. Title: OCCUPATIONAL BURNOUT AMONG NURSES WORKING IN MATERNAL AND CHILD HEALTH CENTERS IN EL BEHEIRA GOVERNORATE Author: Mona Ali. S, Mariam Soliman H., Amal Awad M., Emad Fayek R. International Journal of Novel Research in Healthcare and Nursing ISSN 2394-7330 Vol. 9, Issue 2, May 2022 - August 2022 Page No: 167-186 Novelty Journals Website: www.noveltyjournals.com Published Date: 02-July-2022 DOI: https://doi.org/10.5281/zenodo.6790438 Paper Download Link (Source) https://www.noveltyjournals.com/upload/paper/OCCUPATIONAL%20BURNOUT-02072022-6.pdfInternational Journal of Novel Research in Healthcare and Nursing, ISSN 2394-7330, Novelty Journals, Website: www.noveltyjournals.co

    Mean platelet volume as a predictor of pulmonary hypertension in patients with stable COPD

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    Maha Fathy Mohamed,1 Asmaa Ali,2 Ahmad Abbas,3 Mohammad Shafiq Awad,4 Mohammad Gouda,5 Amany M Sediq61Chest Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt; 2Abbaseya Chest Hospital, MOH, Cairo, Egypt; 3Chest Department, Faculty of Medicine, Zagazig University, Zagazig, 44519, Egypt; 4Cardiology Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt; 5Cardiology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt; 6Clinical and Chemical Pathology Department, Faculty of Medicine, Zagazig University, Zagazig, EgyptBackground: Pulmonary hypertension (PH) is one of the most common complications developed during the course of chronic obstructive pulmonary disease (COPD). Platelet activation plays an important role in its pathophysiology, and mean platelet volume (MPV) is considered a respectable index of platelet activation. The aim of this work is to assess the ability of MPV in predicting PH secondary to COPD as well as its severity.Methods: A cross-sectional study was conducted on 228 stable COPD patients. CBC, echocardiography, and pulmonary function tests were performed.Results: The prevalence of PH in stable COPD patients was high (63%), and the majority of patients had a mild degree (33%). There was no significant association between PH presence with different COPD grade, but, in very severe COPD, severe PH was significantly presented. MPV in COPD patients with PH was significantly higher than those without (9.02±1.14 vs 7.11±0.98, P<0.001). Moreover, a significant statistical rising of MPV with increased severity of PH. Multivariate regression analysis of predictors of PH demonstrated that; MPV is a real predictor of PH in such patients. The likelihood probability of PH increased up to 7-times with increasing one unit of MPV; (OR=6.7). A cut-off value of MPV >7.25 had 96% sensitivity and 76% specificity in predicting PH.Conclusion: MPV was higher in COPD patients with PH and positively correlated with PH severity. If the data are to be confirmed, MPV may be taken into consideration in decision-making and management of COPD patients.Keywords: COPD, mean platelet volume, pulmonary hypertensio
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