5,762 research outputs found
I Remember column in which author Eva LaPlante writes of her visits to sites a
No full textI Remember column in which author Eva LaPlante writes of her visits to sites associated with E. B. White and his book Charlotte\u27s Web
Eva Murray, author of Well Out to Sea , has been a resident of Matinicus Island
No full textEva Murray, author of Well Out to Sea , has been a resident of Matinicus Island since she moved there to teach at the island\u27s one-room schoolhouse in 1987. She discusses the differences between writing from an island and writing about an island as well as her efforts to dispel some stereotypes and myths about Matinicus through her writing
Supercritical Antisolvent Precipitation of Atenolol: The influence of the Organic Solvent and of the Processing Approach.
No full textSupercritical Antisolvent Processing of Atenolol
No full textPoster presentato all'AIChE Annual Meeting (CD), San Francisco (CA – USA), 16-21 novembre 2003, 284d. - Atenolol is a β-blockers drug commonly used in the prevention of heart diseases. The aim of this work is to improve his bioavailability modifying his particle size.
Saturation conditions, at different temperatures, for systems made up with carbon dioxide and solutions of atenolol in methanol, ethanol and isopropanol have been investigated using a variable volume cell.
Atenolol was precipitated from different solutions (5% w/w atenolol-methanol, 5%w/w atenolol-ethanol and 1,65% w/w atenolol/isopropanol) using supercritical carbon dioxide as antisolvent agent.
The release profiles of the micronized atenolol show a general enhancement of the dissolution rate, compared to the one of the untreated drug
Supercritical Antisolvent Precipitation fo Atenolol: Application of the SAS Technique.
No full textIn pharmaceutical field small particles with a controlled size are required to improve the therapeutic action of several drugs and to increase the bioavailability of the active principle. The use of a supercritical fluid, in particular carbon dioxide, as an antisolvent to cause the precipitation and micronization of drugs initially dissolved in a liquid solvent, has been widely investigated in recent years. In this work, the application of the continuous SAS technique to obtain the micronization of atenolol, a β-blockers drug commonly used in the prevention of heart diseases, has been studied. As first step, the saturation conditions, at 313 and 323 K, of carbon dioxide-atenolol-organic solvents (methanol, ethanol and isopropanol) ternary systems have been determined using a variable volume cell. After the determination of the correct working pressure, the atenolol was precipitated starting from organic solutions at different concentrations at 313 K. The size and morphology of the particles obtained have been observed with an electronic microscopy (SEM). The release profiles of the micronized drug showed a general enhancement of the dissolution rate, compared to the one of the untreated atenolol
Obesity of Older School Age Children Based on Physical Activity and Eating Habits
No full textTITLE: Obesity of Older School Age Children Based on Physical Activity and Eating Habits AUTHOR: Bc. Eva Lamačová DEPARTMENT: Department of Education SUPERVISOR: PaedDr. Eva Marádová, CSc. ABSTRACT: This thesis deals with the obesity of older school age children and their dependence on eating and exercising habits. The theoretical part summarizes knowledge regarding overweight and obesity, disease diagnosis, epidemiological trends and complications related to obesity. Emphasis is put on the evaluation of reasons to why this problem occurs, such as disease prevention, dietary and exercise recommendations, its therapy and inclusion of the issue with the secondary school curriculum. The practical part contains research focused on the nutritional status, eating and exercise habits of pupils in secondary school. The survey results are designed for use in pedagogical practice. Usage is targeted for obesity prevention in this age group during Physical Education and Health Education subjects. KEYWORDS: Obesity, overweight, eating habits, exercising habit
Polymer plasticization using supercritical carbon dioxide: experiment and modelling
No full textThe most important effect of sorption of compressed gases and supercritical fluids into glassy polymers is the reduction of the glass transition temperature (Tg). This plasticization effect causes changes in mechanical and thermo-physical properties of the polymers. In this work a thermodynamic study based on experimental and theoretical results is addressed. New data were carried out for the poly (2, 6-dimethyl phenylene oxide) PPO, poly acrylic acid (PAA) and the copolymer vinylpyrrolidone-vinyl acetate P(VP-VA) using an inverse gas chromatographic technique. To model the Tg behavior of diluent-polymer systems a model, that couples the lattice fluid equation of state and the Gibbs-Di Marzio criterion, was used. A parametric study of the influence of the physical properties (lattice coordination number, molecular weight and binary interaction parameter) on the Tg behavior is presented. The thermodynamic model fairly describes the experimental data measured in this work and gives a phenomenological representation of the retrograde vitrification for the systems PPO-CO2, PVP- CO2 and P(VP-VA) - CO2
ANALISIS PENDEKATAN ECONOMIC VALUE ADDED (EVA) TERHADAP KINERJA KEUANGAN PADA PERUSAHAAN MAKANAN DAN MINUMAN DI BURSA EFEK INDONESIA
No full textEconomic Value Added (EVA is one approach to measuring the financial performance of a company by focusing on the creation of value-added enterprises. EVA shows how big the resulting rate of return on the investment made by shareholders. In this paper, the object used by the author is wrong a company engaged in the food and beverage industry in Indonesia Stock Exchange. data used is the consolidated financial statements of the company in 2011-2012. purpose of this paper is to measure the financial performance of the EVA approach to food and beverage companies 2011-2012. Results analysis of the EVA calculation shows that by using the EVA approach, the financial performance of food and beverage companies can experience a volatile period 2011-2012. In 2011 the company's financial performance has improved food and beverage d in the presence of EVA is positive that the company has succeeded in achieving its goal create value-added enterprises. But in 2012 the company's food and beverage show poor financial performance since EVA generated negative worth. This means that in 2012, the company has not been able to create value for the rate of return expected by shareholders or the investment made. Keywords: Economic Value Added (EVA
Solubility of Cholesterol in Supercritical Carbon Dioxide
No full textSupercritical fluid (SCF) extraction offers a good alternative to the current methods of extraction that normally involve the use of organic solvents. To perform this technique it is very important to know the solubility of the drug in the supercritical fluid, usually carbon dioxide.
Several set of solubility data of cholesterol in supercritical CO2 have been reported in literature: however there is a considerable inconsistency in the experimental results.
In this work, the solubility of cholesterol in supercritical carbon dioxide at 313, 323 and 333 K and at pressures between 110-170 bar has been determined.
The experimental data obtained have been compared with literature data and correlated with the Peng Robinson and the PHSC equations of state
NULLITÀ DI PROTEZIONE » E POTERI DEL GIUDICE TRA CORTE DI GIUSTIZIA E SEZIONI UNITE DELLA CORTE
No full textThe “nullità di protezione” in the rulings
of the European Court of Justice and in the recent judgments
of the Joint Sections of the Italian Supreme Court
The Italian legislator provides, as a consequence of the unfairness
of a term in consumers contracts, the remedy of nullity, which can
only occur to the advantage of the consumer, whereby the court has
jurisdiction to declare the term void on its own motion. This is the
concept of “protective nullity“ (nullità di protezione) adopted in
article 36 of the Italian Consumer Code, and framed by the European
Court of Justice. It remains unclear, in such a rule especially when
read in the framework of Italian law, whether the court is entitled to
declare the term void even if the consumer expressly wishes to be
bound by the clause. Moreover, in Italian law, several rules provide
the nullity to the advantage of one party, but they generally state that
the clause or the contract as a whole can be declared void only upon
the weaker ’s party request, without saying anything about the ex
officio declaration. Thus, it remains controversial whether the court
can declare the nullity on its own motion and the regime of art. 1421
c.c. applies, where the rule is silent.
The essay focuses on the general question whether the interest of
the consumer — with no doubt at the basis of the remedy under
consideration — is compatible with the general, public interest and
with the duty of the court to declare the nullity ex officio, perhaps in
contrast with the individual interest of the “protected” party; particularly
where the remedy occurs beyond the special case of the (partial)
nullity of the unfair clause, and the alternative between total nullity or
maintenance of the contract is concerned.
The question isnowaddressed by two recent judgments of the Joint
Sections of the Italian Supreme Court, concerning the powers of the
courts when dealing with the nullity provided to the interest of one
party. The main question referred to the Supreme Court concerned the
duty of the court to declare the contract void on its own motion even
if the party had claimed only the judicial termination in case of nonperformance.
Remarkably, theSupremeCourt, in both the decisions (of
2012 and 2014), assumes a general approach and also considers the role
of the court when the “protective nullity” is concerned. In the first decision—
Cass. SS.UU. n. 2012 n. 14828—the Supreme Court held that,
when the nullity can only occur to the advantage of one party to the
contract, the court has no jurisdiction to declare it on its own motion.
Thiswouldbe the only exception to the general principle which requires
the ex officio declaration of the nullity. In themorerecent decision, Cass.
n. 12642 del 2014, the Joint Sections completely revise their view and
hold that the court must always declare the nullity by its own motion,
but when the nullity is provided in the interest of one party the court
must (only) point out the nullity and not declare it if the party (the
consumer) opposes to that.
The paper criticizes this approach and the following principle
which applies the “Pannon ruling”, and points out how the more
recent Banif Plus has refined that ruling even when the partial nullity
is concerned. If, as in the reasoning of the Supreme Court, the duty of
the court to declare the nullity ex officio aims to guarantee a general
interest and even the values held by the Constitution — the A. argues
— there is no way the party can “oppose” to the ex officio declaration
and express her own (private) interest to preserve the contract. The
paper concludes that the regime of the “protective nullity” provided in
art. 36 Italian Consumer Code, and shaped by the European Court of
Justice, fits (only) to the partial nullity in case of unfairness assessment,
and cannot be assumed as a general rule. Perhaps, the A.
suggests, a different remedy would appear to be an ‘appropriate
consumer protection measure’, in case of violation of imperative rules
devoted to the protection of the weaker party: as Eva Martín Martín
clarifies, the “non-binding nature” of the clause or of the contract
violating statutes for the protection of only one of the parties to the
contract, which the Directives require, should be achieved without
calling in question the concept of nullity
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