1,136 research outputs found
Alumni Authors: Graciela Limon \u2758
No full textAlumni Authors Series - Spring 2012. The William H. Hannon Library was happy to celebrate some of our acclaimed literary alumnus. Each author discussed their newest works and share a few stories from their days at LMU.
Graciela Limon (‘58) - Graciela Limón is a Latina/Chicana writer and a native of Los Angeles, California. She received a Bachelor of Arts Degree in Spanish Literature from Marymount College, Los Angeles, a Master of Arts Degree in the same field from the University of the Americas in Mexico City, followed by a Doctoral Degree in Latin American Literature from the University of California in Los Angeles. Until recently, Limón has been a professor of U.S. Hispanic Literature as well as Chair of the Department of Chicana/o Studies at Loyola Marymount University, Los Angeles, California. She is now Professor Emerita of that university as well as a Visiting Professor at UCLA and UC Santa Barbara.
Limón has written and published reviews and critical work on Mexican, Latin American and Caribbean Literature. She has also written creative fiction, including In Search of Bernabé (1993), which won The Before Columbus Foundation American Book Award (1994). The novel has been released in Spanish under the title En busca de Bernabé (1997). Limón has also published The Memories of Ana Calderón (1994), Song of the Hummingbird (1996), which was published in Spanish under the title of La canción del colebri, in April 2006. The Day of the Moon (1999), was also published in Spanish as El dia de la luna (2006). Erased Faces, which was awarded the 2002 Gustavus Myers Book Award, was published in 2001. Her latest novel, Left Alive, was released in September 2005.
Graciela Limón\u27s fiction has been anthologized in In Other Words: Literature by Latina Writers of the United States, (1994), Latinas: Borderland Voices (1995), The Hispanic Literary Companion (1997), American Mosaic: Multicultural Readings in Context (2001), Herencia (2002), Under the Fifth Sun: Latino Literature from California (2003) and Chicanos, Latinos & Cultural Diversity (2004). In her latest work, The River Flows North, Ms. Limon writes of a small, disparate group of would-be immigrants who hire coyote Leonarda Cerda to guide them from a Sonora border town across the desert into Arizona
Label-free quantitative proteomic profiling of colon cancer cells identifies acetyl-CoA carboxylase alpha as antitumor target of Citrus limon-derived nanovesicles
No full textWe have previously isolated exosome-like nanoparticles from Citrus-limon juice, able to inhibit in vitro and in vivo tumor cell growth. In order to deeply understand the mechanism underlying nanovesicle effects, we performed a proteomic profile of treated colorectal cancer cells. Among the proteins differentially expressed after nanovesicle treatment, we found a significant downregulation of the Acetyl-CoA Carboxylase 1 (ACACA) and we demonstrated that silencing ACACA in cancer cells leads to a reduction of cell growth. Our study proved that the anti-tumor effects of Citrus-limon nanovesicles is partly mediated by lipid metabolism inhibition, in particular via ACACA downregulation
The political attitudes and activities of Antilleans in Port Limon, Costa Rica, 2001
No full textThis study examined the political attitudes and activities of Antilleans in Port Limon, Costa Rica. The study was based on the premise that Antilleans believe that Costa Rica is not a nation of racial democracy, which is evidenced by the lack of representation of Antilleans in government, media, and private industry positions. A survey, translated into English and Spanish, was used to identify the perceptions of Antilleans regarding racial equality, political power, the role of the government, and the plight of Antilleans in Port Limon, Costa Rica. The study revealed that Antilleans are subjected to stereotyping, amalgamation, alienation, and insults to their culture
Isolation and characterization of Citrus limon L. derived nanovesicles: potential use as antineoplastic agent
No full textWe isolated and characterized nanovesicles from edible Citrus limon with size and composition
similar to mammalian-derived exosomes. Furthermore we show an in vitro and in vivo anti-proliferative and pro-apoptotic effect of these vesicles. This study opens to the possibility of using this natural plant-derived nanovesicles as antineoplastic agents
Microtransplantation of cellular membranes from squid stellate ganglion reveals ionotropic GABA receptors
No full textAuthor Posting. © Marine Biological Laboratory, 2013. This article is posted here by permission of Marine Biological Laboratory for personal use, not for redistribution. The definitive version was published in Biological Bulletin 224 (2013): 47-52.The squid has been the most studied cephalopod, and it has served as a very useful model for investigating the events associated with nerve impulse generation and synaptic transmission. While the physiology of squid giant axons has been extensively studied, very little is known about the distribution and function of the neurotransmitters and receptors that mediate inhibitory transmission at the synapses. In this study we investigated whether γ-aminobutyric acid (GABA) activates neurotransmitter receptors in stellate ganglia membranes. To overcome the low abundance of GABA-like mRNAs in invertebrates and the low expression of GABA in cephalopods, we used a two-electrode voltage clamp technique to determine if Xenopus laevis oocytes injected with cell membranes from squid stellate ganglia responded to GABA. Using this method, membrane patches containing proteins and ion channels from the squid's stellate ganglion were incorporated into the surface of oocytes. We demonstrated that GABA activates membrane receptors in cellular membranes isolated from squid stellate ganglia. Using the same approach, we were able to record native glutamate-evoked currents. The squid's GABA receptors showed an EC50 of 98 μmol l–1 to GABA and were inhibited by zinc (IC50 = 356 μmol l–1). Interestingly, GABA receptors from the squid were only partially blocked by bicuculline. These results indicate that the microtransplantation of native cell membranes is useful to identify and characterize scarce membrane proteins. Moreover, our data also support the role of GABA as an ionotropic neurotransmitter in cephalopods, acting through chloride-permeable membrane receptors.Grass Foundation Fellowships to
L.C. and A.L. (www.grassfoundation.org). L.C. was additionally
supported by the Ph.D. in Neurophysiology program
of the University of Rome “La Sapienza.” All authors
were Grass Fellows. This work was supported by Ministero
della Sanita` Antidoping and PRIN project 2009 (to E.P.)
The geohistoriographic novel. Interdiscursive space of Koncert Wielkiej Niedźwiedzicy of Jerzy Limon
No full textArtykuł jest interpretacją powieści Jerzego Limona Koncert Wielkiej Niedźwiedzicy. Kantata na
jedną ulicę, siedem gwiazd i dwa głosy, będącej przykładem literatury zwrotu topograficznego.
Powieść opowiada historię ulicy w Sopocie, przy której mieszka autor-narrator. Powieść
określam mianem geohistoriograficznej, gdyż autor przedstawia w niej przestrzeń miasta —
konkret geograficzny — jako tekst-palimpsest, w którym, warstwa po warstwie, odczytuje
przeszłość.This article provides an interpretation of the novel of Jerzy Limon Koncert Wielkiej Niedźwiedzicy. Kantata na jedną ulicę, siedem gwiazd i dwa głosy, which is an example of the literature of the topographical turn. This novel tells stories of one street in Sopot (Haffner street), where
the author-narrator lives. This novel implements not only the assumptions of geo-poetics but may also be called geohistoriographic, since the author presents a geographic concrete, the space of a city as a conveyor of historic knowledge, for the geographic space is for Limon
the text in which one may read the past. The subject matter of the novel is a street fulfilling just the function of a text, or actually text-palimpsest, which is composed with layers of meanings recorded by particular historic eras
Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death
No full textNanosized vesicles are considered key players in cell to cell communication, thus influencing physiological and pathological processes, including cancer. Nanovesicles have also been found in edible-plants and have shown therapeutic activity in inflammatory bowel diseases; however information on their role in affecting cancer progression is missing.Our study identify for the first time a fraction of vesicles from lemon juice (Citrus limon L.), obtained as a result of different ultracentrifugation, with density ranging from 1,15 to 1,19 g/ml and specific proteomic profile. By using an in vitro approach, we show that isolated nanovesicles inhibit cancer cell proliferation in different tumor cell lines, by activating a TRAIL-mediated apoptotic cell death. Furthermore, we demonstrate that lemon nanovesicles suppress CML tumor growth in vivo by specifically reaching tumor site and by activating TRAIL-mediated apoptotic cell processes. Overall, this study suggests the possible use of plant-edible nanovesicles as a feasible approach in cancer treatment
Physical dance performance: An investigation into the development of a performance technique based on the integration of certain Korean dance technique and contemporary Western styles of dance and physical theatre
No full textThis thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 04/10/2001.This development of a performer practice that integrates elements of traditional Korean dance technique and Western forms of physical theatre and contemporary dance is based on an approach to internal understanding and external execution. Central to the work is the concept of body energy, or Ki. This ancient Eastern term is translated into a contemporary practice that enables a performer to engage mental and physical training. Breath and the use of breath in performing are the principal means of achieving this level of engagement
The handling and storage of dangerous goods in Costa Rica : case study - Port Limon
No full textThe port is considered an important area from various points of view. Economically, the port is a service center which is intended to make a profit and technically, it is a strategic point for the success of maritime transportation. The safe handling of dangerous substances plays an important role in the level of safety in ports. Safety in ports depends very much on the availability of information about dangerous cargo expected to reach the port, methods of handling such cargo up to its final transport away from the port which requires special precautionary steps such as a complete awareness and ability to act immediately and to ensure safe operations in the port. The handling of dangerous goods should be performed according to a set system/rules and regulations incorporating a reference to the acceptable period during which they can be safely stored. With this dissertation the author will attempt. to improve the conditions of safety in the ports of Limon and Moin by formulating rules and regulations based on the relevant IMO instruments regarding the handling and storage of dangerous goods within port areas, as well giving personal points of view. Special emphasis is placed on the warehouses of the Port of Limon which still are a problem that could cause catastrophic effects on the safety of personnel, ships, equipment and harm the environment. Safety is one of the most important aspects, which must be considered by the specialized competent authority in order for such transport facilities and maritime activities to be developed and improved. This paper also aims to cover and to set the responsibilities of the different authorities dealing with dangerous goods. Finally the objective of this dissertation is to improve the safety of handling and storage of dangerous goods in port areas, through recommendations and guidelines which have to put into practice as soon as possible in the ports of Limon and Moin
- …
