709 research outputs found
Strategies to improve the performances of bakery products made from ancient wheat’s
No full textThe growing consumers’ attention regarding the inclusion of foods able to provide health benefits in one’s diet, is currently a theme of fundamental importance. Between these products, ancient wheat’s and whole wheat flours seem to be the most appealing in the cereal industry thanks to their nutritional content. Nevertheless, ancient wheat’s show worse rheological and technological performances compared to modern cultivars, in particular when using whole wheat flour. According to Migliorini, et al. (2016), the content of starch and protein is strongly influenced by annual variability and agronomic practices. This highlights the need for further investigation to understand the relationship between different agronomic practices and the rheological and technological properties of flours and dough’s made from ancient wheat’s. Furthermore, the greatest challenge for the bakery industry still remains the improvement of the technological properties of bakery products made from ancient wheat’s. In this paper, some of the strategies aimed to face this challenge are proposed. Starting from the improvement of the rheological properties of dough’s made from ancient wheat, Cappelli, et al. (2018) provided a rheological study which allows to identify the optimal water content to be added, through models represented by level curves diagrams. Moreover, regarding the improvement of bakery products based on ancient wheat, the sourdough fermentation (Saa, et al. 2017) and the reduction of free lipid in the doughs (Collar & Angioloni, 2014) seems to be the most interesting strategies. Finally, future strategies finalized to improve the technological properties of bakery products made from ancient wheat’s are related to the assessment of suitability and bread-making aptitude of ancient wheat flours blended with the most interesting and innovative sources of proteins, i.e. legume and insect flours
Gene therapy for adenosine deaminase deficiency.
No full textIn the last decade, gene therapy for adenosine deaminase deficiency has been developed as a successful alternative strategy to allogeneic bone marrow transplant and enzyme replacement therapy. Infusion of autologous hematopoietic stem cells, corrected ex vivo by retroviral vectors and combined to low-intensity conditioning regimen, has resulted in immunologic improvement, metabolic correction, and long-term clinical benefits. These findings have opened the way to applications of gene therapy in other primary immune deficiencies using novel vector technology
PISA: A measure of Preference In Selection of Arguments to model verb argument recoverability
No full textOur paper offers a computational model ofthe semantic recoverability of verb arguments,tested in particular on direct objects and In-struments. Our fully distributional model isintended to improve on older taxonomy-basedmodels, which require a lexicon in addition tothe training corpus. We computed the selec-tional preferences of 99 transitive verbs and173 Instrument verbs as the mean value of thepairwise cosine similarity between their argu-ments (a weighted mean between all the argu-ments, or an unweighted mean with the top-mostkarguments).Results show that ourmodel can predict the recoverability of objectsand Instruments, providing a similar result tothat of taxonomy-based models but at a muchcheaper computational cost
La valutazione dei crediti tra dottrina, normativa e prassi: elementi per un confronto alla luce dei principi contabili internazionali IAS/IFRS
No full textIl processo di armonizzazione contabile in atto a livello europeo ha subito in questi ultimi anni una considerevole accelerazione, per effetto, da un lato, dell’introduzione dei Principi Contabili Internazionali IAS/IFRS, rivolta, però, ad una ristretta cerchia di imprese, e, dall’altro lato, in conseguenza dell’avvio di un processo di modernizzazione delle Direttive Contabili, finalizzato a limitare quanto più possibile l’esistenza di un consistente gap informativo a discapito delle imprese non rientranti nell’ambito di ap-plicazione dei suddetti principi contabili.
A fronte di un simile processo, si ha chiara la percezione che la strada intrapresa da-gli organismi che si occupano di normazione contabile segni un deciso scarto rispetto al passato: infatti, la necessità delle imprese di predisporre un’informazione economico-finanziaria che soddisfi le diverse esigenze conoscitive di una platea di destinatari ben più numerosa ed in possesso di maggiori competenze rispetto al passato, ha comportato il ripensamento delle finalità dei bilanci, dei principi che ne informano la redazione e, di conseguenza, dei criteri di valutazione che guidano la determinazione dei valori da ri-portare al loro interno.
Prendendo spunto da questi aspetti, il presente contributo intende analizzare in chia-ve evolutiva il tema della valutazione e rappresentazione dei crediti nei bilanci delle im-prese, ponendo a confronto i presupposti e le risultanze del pensiero economico-aziendale in materia, con quelli che animano, secondo un’ottica attuale e prospettica, lo scenario normativo del nostro Paese. L’obiettivo è quello di evidenziare gli elementi fondamentali su cui poggia il suddetto processo evolutivo, anche per coglierne la portata e giudicarne la coerenza rispetto al fine perseguito.
L’analisi svolta pone in evidenza le molteplici criticità connesse all’adozione di un sistema di regole che, al fine di realizzare gli obiettivi suesposti, apporta sostanziali mo-difiche ai criteri di rilevazione, valutazione e rappresentazione in bilancio delle opera-zioni creditizie, e chiede alle imprese non soltanto di reindirizzare la prassi fino ad ora seguita, ma di ripensare ai propri sistemi gestionali, soprattutto quelli a supporto del controllo e della misuraizone dei rischi che, quand’anche già in uso, potrebbero rivelarsi non in grado di rispondere in maniera soddisfacente al nuovo e più elevato livello di in-formativa da offrire all’esterno.The harmonisation project of the accounting rules in the European Union has been receiving a strong acceleration due, on the one hand, to the adoption of International Accounting Standards – that was addressed to a limited whole of European companies – and, on the other hand, to the modernisation of the Accounting Directives in order to enhance the comparability between the annual and consolidated accounts of Community companies which apply IAS and those which do not.
As a result of this process, there is a clear awareness of the significant gap from the best practice: companies need to prepare and present their financial statements in order to satisfy the common needs of a whole of external users that is much wider and owns more financial competences than in the past. This fact involves thinking over the objective of financial statements, the characteristics that determine the usefulness of information given and the the definition, recognition and measurement of the elements from which financial statements are constructed.
Taking its cues from these themes, this study analyzes the recognition, measurement and presentation issues about loans, throughout the comparison between the fundamentals of the Italian Accounting Studies and the ones underlying the national legislative scenario, on a present and perspective viewpoint. The aim is to show the fundamental elements the evolutionary process rests upon and valuate their consistency with the purpose of harmonisation.
The analysis carried out in this study shows the various problems related to the adoption of a new system of rules that will demand companies not only to modify their practice of accounting for loans in their annual and consolidated financial statements, but also to reconsider their risk management policies, in order to satisfy the higher level of disclosure required by the International Accounting Standards
Healthcare-associated infections and nursing leadership: A systematic review
No full textHealthcare-associated infections are strictly related to healthcare practices. A head nurse stimulates and motivates nurses, boosts nurses’ job performance and satisfaction, and can influence adverse event development.
To explore the relationship between healthcare-associated infections and head nurse leadership style.
A systematic review was conducted. The search was conducted from 1973 until March 2022 on PubMed, Cochrane Library, Scopus, CINAHL, Web of Science, Embase, and APA PsycInfo databases. The review followed the Joanna Briggs Institute Manual for Evidence Synthesis and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. A thematic synthesis and critical appraisal of the included studies have been conducted.
Eight articles were included in this review. Head nurses’ leadership, supported by the organization, can positively influence the job performance and job satisfaction of nurses by reducing infection rates associated with vascular access and urinary catheters.
Authentic and transformational nurse leadership styles can foster targeted interventions and improvements tailored to preventing and controlling healthcare-associated infections. Even if there is limited evidence, the results support that the occurrence of infections can be reduced by leadership strategies implemented by head nurses
Reply to External validation of an individual prognostic calculator after trans-arterial chemo-embolization for hepatocellular carcinoma
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Trans-arterial embolization for hepatocellular carcinoma: with or without epidoxorubicin?
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Improving whole wheat dough tenacity and extensibility: A new kneading process
No full textWhole wheat bread is an important source of dietary fiber, vitamins, minerals, and antioxidants. Unfortunately, the addition of bran and middlings lead to significant rheological problems, while the bread that is produced has lower volume and increased crumb density. For these reasons, bakers need to find new strategies. This paper presents a new procedure in which the addition of bran and middlings during kneading is delayed. Our laboratory-scale experiment assessed differences in dough rheology and bread characteristics as a function of three percentages of bran and middlings content (10%, 20%, and 30%) and five addition times (0, 2, 3.5, 5, and 6.5 min after kneading begins). Total kneading time was 8 min both in rheological and breadmaking tests. Results show ameliorative effects related to the delayed addition of bran and middlings during kneading. In particular, improved dough rheology (i.e. lower tenacity and tenacity/extensibility ratio, accompanied by higher extensibility), and bread characteristics (i.e. greater specific volume) were obtained with addition at 2 min. The proposed strategy improves both dough rheology and whole wheat bread characteristics, and could guide the development of specific kneading machines for whole wheat flours
Senatore Cappelli wheat derived biomolecules exert anti-inflammatory and anti-oxidant activity
No full textMuch attention has been focusing on wheat derived extracts for their health-promoting functions, as a source of bioactive molecules and nutraceuticals.
We evaluated in a multimethodological approach the anti-inflammatory and anti- oxidant properties of hydroalcoholic extracts obtained from husks, grains, flour and pasta derived from durum wheat belonging to the ancient cultivar “Senatore Cappelli”, assessing their potential as bioactive compound sources in terms of phytochemical, antioxidant, and anti-inflammatory properties. The content of total phenolic compounds and total flavonoid and antioxidant activity were carried out by ABTS and DPPH assays. The cytotoxicity of the green extracts was evaluated by MTS and Trypan blue assays in the human U937 and murine microglia BV2 cells, showing that extracts do not affect microglia viability. We analyzed the inflammatory phenotype of cells pretreated by wheat extracts and then cultured in the presence or absence of LPS. We analyzed i) the expression of mRNAs for: IL-1 beta, IL-6, TNF-alpha, IL-17, IL-10, TGF-beta; ii) the expression of mRNAs of the main M1 and M2 polarization markers, including iNOS, ARG1, CD206, COX-2 and transcriptional factors TBX21, STAT1, STAT3, STAT4, STAT6, RORC, GATA3, FOXP3 and NR4A2; iii) the expression of anti-oxidant factors and enzymes (Nrf2, SOD1 and GPX). Extracts were shown to be devoid of any pro-inflammatory activity because they do not increase the expression of M1 markers. Conversely, expression of ARG-1, CD206, Chil3 mRNA was induced by the extracts also after the addition of LPS, reverting microglia toward an anti-inflammatory phenotype. Extracts of “Senatore Cappelli” wheat derivatives restore NRF2 expression related to the upregulation of SOD1, an antioxidant gene. It is known that NRF2 pathways counteract ROS production and inflammation in neurodegenerative disorders, suggesting that stimulation of NRF2 factor could play a key role as a therapeutic approach
Il "Criticón" tra geografia e simbolismo. La difficile questione dell’ambientazione dell’"Hiermo de Hipocrinda"
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