334 research outputs found
A randomized study on postrelapse disease-free survival with adjuvant mistletoe versus oral etoposide in osteosarcoma patients
No full textBackground. Osteosarcoma is a highly malignant bone tumour. After the second relapse, the 12-month postrelapse disease-free survival (PRDFS) rate decreases below 20%. Oral Etoposide is often used in clinical practice after surgery as an "adjuvant" outside any protocol and with only limited evidence of improved survival. Viscum album fermentatum Pini (Viscum) is an extract of mistletoe plants grown on pine trees for subcutaneous (sc) injection with immunomodulatory activity. Methods. Encouraged by preliminary findings, we conducted a study where osteosarcoma patients free from disease after second metastatic relapse were randomly assigned to Viscum sc or Oral Etoposide. Our goal was to compare 12-month PRDFS rates with an equivalent historical control group. Results. Twenty patients have been enrolled, with a median age of 34 years (range 11-65) and a median follow-up time of 38.5 months (3-73). The median PRDSF is currently 4 months (1-47) in the Etoposide and 39 months (2-73) in the Viscum group. Patients getting Viscum reported a higher quality of life due to lower toxicity. Conclusion. Viscum shows promise as adjuvant treatment in prolonging PRDFS after second relapse in osteosarcoma patients. A larger study is required to conclusively determine efficacy and immunomodulatory mechanisms of Viscum therapy in osteosarcoma patients. © 2014 Alessandra Longhi et al
Alcune precisazioni e nuove proposte per il catalogo di Benvenuto Tisi detto il Garofalo
No full textL'articolo arricchisce di alcuni dipinti il catalogo di Garofalo, con riferimento alla fase giovanile e alla prima maturità. Il reperimento di nuovi elementi è stato possibile grazie alla consultazione della Fototeca della Fondazione di studi di storia dell'arte Roberto Longhi durante i mesi in cui l'autrice è stata borsista presso l'Istituto
cat. no. 32: “Pietro Falca, detto Pietro Longhi, The Confession (Inv.1890, n. 9275)
No full textScheda di un dipinto di Pietro Longhi dedicato al sacramento della Confessione nella Galleria degli uffiz
FIGURE 1 in A new species of Sporobolus (Poaceae, Chloridoideae) from Trindade Island, Brazil, with comments on the distribution of the genus in the South Atlantic
No full textFIGURE 1. Sporobolus nesiotioides (the holotype) A. Lateral view of spikelet showing the two glumes, lemma and palea; B. Glumes in lateral view; C. Caryopsis; D. Habit. E. Transverse section of the leaf showing the naturally convolute position. (Illustrations: A–C by H. M. Longhi-Wagner and Anelise Scherer; D–E by R. J. V. Alves).Published as part of Longhi-Wagner, Hilda M., Alves, Ruy J.V., Da Silva, Nílber G. & Guimarães, Alessandra R., 2013, A new species of Sporobolus (Poaceae, Chloridoideae) from Trindade Island, Brazil, with comments on the distribution of the genus in the South Atlantic, pp. 13-21 in Phytotaxa 144 (1) on page 14, DOI: 10.11646/phytotaxa.144.1.2, http://zenodo.org/record/509999
Dephasing-Induced Mobility Edges in Quasicrystals
No full textMobility edges (ME), separating Anderson-localized states from extended states, are known to arise in the single-particle energy spectrum of certain one-dimensional lattices with aperiodic order. Dephasing and decoherence effects are widely acknowledged to spoil Anderson localization and to enhance transport, suggesting that ME and localization are unlikely to be observable in the presence of dephasing. Here it is shown that, contrary to such a wisdom, ME can be created by pure dephasing effects in quasicrystals in which all states are delocalized under coherent dynamics. Since the lifetimes of localized states induced by dephasing effects can be extremely long, rather counterintuitively decoherence can enhance localization of excitation in the lattice. The results are illustrated by considering photonic quantum walks in synthetic mesh lattices.The author acknowledges the Spanish State Research Agency, through the Severo Ochoa and Maria de Maeztu
Program for Centers and Units of Excellence in R&D (Grant No. MDM-2017-0711).Peer reviewe
The high altar of S. Carlo ai Catinari, Rome
No full textInediti documenti hanno permesso di ricostruire la storia della splendida macchina barocca, ovvero l'altare di San Carlo ai Catinari, progettato da Martino Longhi. L'altare presenta una pala di Pietro da Cortona della quale è stato qui pubblicato l'inedito bozzetto
Caravaggio a Milano, 1951. Il dibattito sulla carta stampata: critica e militanza
No full textLa mostra dedicata a Caravaggio, che si tenne a Milano nella primavera del 1951 a cura di Roberto
Longhi, rappresentò un momento culminante degli studi caravaggeschi della prima metà del XX secolo
e segnò uno spartiacque nella storia critica del maestro lombardo. In questa sede si prendono in esame
testimonianze sinora poco valutate, ovvero le recensioni e gli articoli apparsi sulla stampa periodica non
specialistica e sui quotidiani, che offrono materia per una riflessione più ampia sul tema del realismo.
Si tratta di attestazioni cariche della vivacità del momento storico, di cui traducono polemiche,
sensazioni, opinioni in grado di restituire la tensione tipica dell’evento espositivo. Tra gli attori di questa
complessa vicenda si trovano editorialisti, pubblicisti, letterati e critici militanti, quali Leonardo Borgese,
Alfredo Mezio, Mario De Micheli, Elio Vittorini, ma anche registi e documentaristi come Umberto
Barbaro, che fu collaboratore di Longhi.The exhibition dedicated to Caravaggio, which was held in Milan in the spring of 1951 by Roberto Longhi,
was a culmination of Caravaggio studies in the first half of the twentieth century and marked a watershed
in the history of criticism of the Lombard master. Here the author examines some unappreciated
evidences, that is the reviews and the articles published in periodicals and newspapers, which offer
material for a broader reflection on the theme of realism. They are proof of the liveliness of the historic
moment, of which translate controversy, feelings, opinions that can return the typical tension of the
exhibition. Among the actors of this complex situation there are columnists, publicists, writers and critics,
such as Leonardo Borgese, Alfredo Mezio, Mario De Micheli, Elio Vittorini, but also directors and
documentarians like Umberto Barbaro
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