2,384 research outputs found
Epithelial‐immune cell interactions in allergic diseases
No full textAbstract Epithelial/immune interactions are characterized by the different properties of the various epithelial tissues, the mediators involved, and the varying immune cells that initiate, sustain, or abrogate allergic diseases on the surface. The intestinal mucosa, respiratory mucosa, and regular skin feature structural differences according to their primary function and surroundings. In the context of these specialized functions, the active role of the epithelium in shaping immune responses is increasingly recognizable. Crosstalk between epithelial and immune cells plays an important role in maintaining homeostatic conditions. While cells of the myeloid cell lineage, mainly macrophages, are the dominating immune cell population in the skin and the respiratory tract, lymphocytes comprise most intraepithelial immune cells in the intestine under healthy conditions. Common to all surface epithelia is the fact that innate immune cells represent the first line of immunosurveillance that either directly defeats invading pathogens or initiates and coordinates more effective successive immune responses involving adaptive immune cells and effector cells. Pharmacological approaches for the treatment of allergic and chronic inflammatory diseases involving epithelial barriers target immunological mediators downstream of the epithelium (such as IL‐4, IL‐5, IL‐13, and IgE). The next generation of therapeutics involves upstream events of the inflammatory cascade, such as epithelial‐derived alarmins and related mediators
Contentious politics in the Middle East: Political opposition under authoritarianism
No full textScholarship examining the governments in the Middle East and North Africa rarely focuses on opposition movements, since those countries tend to be ruled by a centralized, often authoritarian government. However, even in an oppressive state, there are civil society and oppositional forces at work. The contributors to Contentious Politics in the Middle East reveal how such forces emerge and are manifested in nondemocratic states across the region. In most cases, the essays offer a comparative perspective, highlighting similarities across political borders. Providing historical context for current events, they examine the sociopolitical situations in Egypt, Syria, Jordan, Kuwait, Bahrain, Iraq, Morocco, Tunisia, Lebanon, and Algeria and analyze the role of Islam in Arab states\u27 governments and in the opposition movements to them. They also demonstrate that not all opposition forces propose the overthrow of authority and point out the various forms opposition takes in societies that leave little room for political activism. The contributors to the volume are drawn from countries across three continents and bring backgrounds in political science, conflict resolution, and history. Challenging the assertion that state-society relations are limited to coercive top-down arrangements in authoritarian regimes, the book will inspire debate on the topic of contentious political participation within the region as well as in similar settings throughout the world. © 2010 by Holger Albrecht. All rights reserved.https://fount.aucegypt.edu/faculty_books/1038/thumbnail.jp
Albrecht Götze et Holger Pedersex, Muršiliš Sprachlähmung. Ein hethitischer Text mit philologischen und linguistischen Erǒrterungen, VII-83 p. (Det Kgl. Danske Videnskabernes Selskab. Historisk-filologiske Meddelelser, XXI, 1). Copenhague, Levin et Munksgaard, 1934, Kr. 4,60
No full textBergsland Knut. Albrecht Götze et Holger Pedersex, Muršiliš Sprachlähmung. Ein hethitischer Text mit philologischen und linguistischen Erǒrterungen, VII-83 p. (Det Kgl. Danske Videnskabernes Selskab. Historisk-filologiske Meddelelser, XXI, 1). Copenhague, Levin et Munksgaard, 1934, Kr. 4,60. In: Revue hittite et asianique, 3e année, fascicule 19-20, 1935. pp. 142-143
Mediacups: Experience with Design and Use of Computer-Augmented Everyday Artefacts
No full textOur view of ubiquitous computing is artefact-centred: in this view, computers are considered as secondary artefacts that enable items of everyday use as networked digital artefacts. This view is expressed in an artefact computing model and investigated in the Mediacup project, an evolving artefact computing environment. The Mediacup project provides insights into the augmentation of artefacts with sensing, processing, and communication capabilities, and into the provision of an open infrastructure for information exchange among artefacts. One of the artefacts studied is the Mediacup itself, an ordinary coffee cup invisibly augmented with computing and context-awareness. The Mediacup and other computeraugmented everyday artefacts are connected through a network infrastructure supporting loosely-coupled spatially-defined communication
A Note on the Equivalence of Rationalizability Concepts in Generalized Nice Games
No full textMoulin (1984) describes the class of nice games for which the solution concept of point-rationalizability coincides with iterated elimination of strongly dominated strategies. As a consequence nice games have the desirable property that all rationalizability concepts determine the same strategic solution. However, nice games are characterized by rather strong assumptions. For example, only single-valued best responses are admitted and the individual strategy sets have to be convex and compact subsets of the real line R1. This note shows that equivalence of all rationalizability concepts can be extended to multi-valued best response correspondences. The surprising finding is that equivalence does not hold for individual strategy sets that are compact and convex subsets of Rn with n>1.
Replication Data for: Are Sleepy Punishers Really Harsh Punishers?: Comment
No full textThis data set contains data (USSCdata.dta) and a script (Spamann_comment_Cho_dataanalysis.do) to recreate models 2,3, 5, and 6 of table 1 in Holger Spamann, Are Sleepy Punishers Really Harsh Punishers?: Comment, Psychological Science (forthcoming 2017). It also contains the raw data from the USSC (opafy92nid.dta through opafy03nid.dta), the USSC's codebooks explaining those data, and a second script (Spamann_comment_Cho_dataassembly_forweb.do) that generates USSCdata.dta from this raw data.
The data and scripts are written for Stata (version 14). The analysis script calls user-written packages estout and reghdfe.
Note that the scripts build and analyze ALL data mentioned in my article (i.e., not only models 2, 3, 5, and 6). The other data are available from: (a) TRAC data: by emailing [email protected] (TRAC will provide the data only to researchers affiliated with subscriber institutions); (b) Cho et al.’s original data: from the lead author of the original article, Kyoungmin Cho (I do not have permission to share their data).
If you do not have access to the other data or want to restrict your work to the USSC data, you should comment out the parts of the script concerning other data.
More information on running the scripts is contained in their first lines
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