197,263 research outputs found
L'insegnamento della storia economica medievale : problemi di metodo e individuazione dei "saperi minimi"
No full textL’esperienza del porgere: i musei di Franco Albini e Carlo Scarpa
No full textIl saggio ricostruisce la carriera di Albini museografo attraverso alcune sue opere significative allo scopo di indagarne la metodologia progettuale
Transformation-Based Musical Graphs
No full textThe abstract focuses on graphical representations of musical elements related to pitches, chords, and harmonic concepts in general that are attributable to modern graphs dating back no later than to the 17th century, including notable illustrations by Marin Mersenne, Leonhard Euler, Carl Ernst Naumann, Ottikar Hostinsky, Artthur Von Oettingen, and Hugo Riemann. The aim of the paper is to research construction strategies to build transformation-based graph, including original illustrations developed by Albini and Bernardi
D. August Petræi, Curiose Gedancken von der Lüsternheit Der Schwangern-Weiber und vom Brechen, D. Bernhard Albini von der Entzückung Oder Hinfallung / aus dem Lateinischen übersetzet vom M. M
No full textD. AUGUST PETRÆI, CURIOSE GEDANCKEN VON DER LÜSTERNHEIT DER SCHWANGERN-WEIBER UND VOM BRECHEN, D. BERNHARD ALBINI VON DER ENTZÜCKUNG ODER HINFALLUNG / AUS DEM LATEINISCHEN ÜBERSETZET VOM M. M
D. August Petræi, Curiose Gedancken von der Lüsternheit Der Schwangern-Weiber und vom Brechen, D. Bernhard Albini von der Entzückung Oder Hinfallung / aus dem Lateinischen übersetzet vom M. M (1)
Cover (1)
Titelblatt (2)
Von der Gelüstigkeit oder Lüsternheit der schwangern Weiber (4)
Vom Brechen (12)
Von der Entzückung (28
Photochemistry of some fluoroquinolones. Effect of pH and chloride ion
No full textA 6-fluoroquinolone (norfloxacin) and the naphthyridine analogue enoxacin give the corresponding 6-hydroxy derivatives by irradiation in water at pH 7.2 and, with lower efficiency, at pH 4.5 and 10. At pH 1 no defluorination takes place and the piperazinyl side chain is degraded. The 6,8-difluoro derivative lomefloxacin is defluorinated selectively from position 8 over the entire pH range considered (pH 1 to 10). The intermediate cation in position 8 does not add water and rather undergoes insertion into the β-CH bond of the neighboring N-ethyl group. The cation adds chloride, however. The structure–photoreactivity relationship for fluoroquinolones and the relation with the known phototoxicity of these compounds are commented upon
From abandonment to fosterage : stories of children in late Fifteenth Century Milan
No full textLe pratiche di affido dei fanciulli, poste in essere dagli enti caritativi e assistenziali bassomedievali per dare soluzione al problema dell’infanzia abbandonata, si giocavano tra i due poli rappresentati dall’adozione e dal cosiddetto fosterage, declinandosi in gradazioni che andavano dall’affido temporaneo alla “quasi-adozione”. L’affidamento dei fanciulli è esaminato nel contesto demografico e sociale di Milano dove, nella seconda metà del Quattrocento, la società nel suo complesso, e gli ospedali in particolare, furono chiamati a farsi carico di numeri sempre più elevati di bambini abbandonati. L’attività dell’Ospedale Maggiore è stata studiata, per gli anni 1472-1531, attraverso un registro riguardante le « Consegne di trovatelli e di figli dell’ospedale »: questa fonte è preziosa per la varietà dei casi testimoniati ma anche perché rispecchia, dal punto di vista formale, la progressiva definizione di una prassi di affidamento che si traduce in una tutela sempre maggiore dei bambini e si sviluppa contestualmente all’elaborazione, da parte dell’ospedale, di una propria identità istituzionale e amministrativa.The complex practices of children custody, employed in by late medieval charitable institutions to solve the problem of children abandonment, could have different outcomes, ranging from the “real” adoption to the so-called fosterage, from the temporary custody to the "quasi-adoption". The practices of children custody have been examined in the demographic and social context of Milan, where, in the second half of the fifteenth century, the society as a whole, and hospitals in particular, had to address the problem represented by the increasingly high numbers of abandoned children.
The activity of the Ospedale Maggiore has been studied, for the years between 1472 and 1531, through a register regarding the « Consegne di trovatelli e di figli dell’ospedale ». This source is valuable for the variety of cases attested but also because it reflects, from a formal point of view, the definition of a custody practice that results in increased protection for abandoned children, in connection to the definitition of the hospital’s administrative and institutional identity
Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size.
No full textHuman immunodeficiency virus type 1 (HIV-1) Tat protein is released from infected cells. Extracellular Tat enters the cell where it stimulates the transcriptional activity of HIV-long terminal repeat (LTR) and of endogenous genes. Heparin modulates the angiogenic (Albini, A., Benelli, R., Presta, M., Rusnati, M., Ziche, M., Rubartelli, A., Paglialunga, G., Bussolino, F., and Noonan, D. (1996) Oncogene 12, 289-297) and transcriptional (Mann, D. A., and Frankel, A. D. (1991) EMBO J. 10, 1733-1739) activity of extracellular Tat. Here we demonstrate that heparin binds specifically to recombinant HIV-1 Tat produced as glutathione S-transferase (GST) fusion protein and immobilized on glutathione-agarose beads. Heparin and heparan sulfate (HS), but not dermatan sulfate, chondroitin sulfates A and C, hyaluronic acid, and K5 polysaccharide, competed with 3H-labeled heparin for binding to immobilized GST-Tat and inhibited HIV-LTR transactivation induced by extracellular GST-Tat. Selective 2-O-, 6-O-, total-O-desulfation, or N-desulfation/N-acetylation dramatically reduced the capacity of heparin to bind GST-Tat. Totally-O-desulfated and 2-O-desulfated heparins also showed a reduced capacity to inhibit the transactivating activity of GST-Tat. Very low molecular weight heparins showed a significant decrease in their capacity to bind GST-Tat and to inhibit its LTR transactivating activity when compared with conventional 13.6-kDa heparin. However, when 3.0-kDa heparin was affinity chromatographed on immobilized GST-Tat to isolate binding and non-binding subfractions, the Tat-bound fraction was >/=1,000 times more potent than the unbound fraction in inhibiting the transactivating activity of GST-Tat. The results demonstrate that Tat interacts in a size-dependent manner with heparin/HS and that high affinity Tat-heparin interaction requires at least some 2-O-, 6-O-, and N-positions to be sulfated. The Tat binding activity of the glycosaminoglycans tested correlates with their capacity to affect the transactivating activity of extracellular Tat, indicating the possibility to design specific heparin/HS-like structures with Tat-antagonist activity
De Didius Julianus aux Nummii Albini
No full textUne reconsidération de l’arbre généalogique de Didius Julianus tel que le livre l’Histoire Auguste permet d’établir que ce prince avait comme bisaïeul un haut personnage qui était aussi un bisaïeul maternel de Marc Aurèle. Didius Julianus tenta de prendre le pouvoir parce qu’il était apparenté (tout comme sans doute son épouse
Manlia Scantilla) aux Antonins. Sa famille, assez étoffée, comportait des Nummii Albini
dont la généalogie est revue à la lueur de documents récents réinterprétés. Il était pareillement apparenté à Clodius Albinus, ce qui amène une relecture des événements des années 193-196. Face à ce clan familial, Septime Sévère aura le souci de se créer une légitimité antonine en se disant fils de Marc Aurèle et en faisant nommer son fils M. Aurelius Antoninus, revendiquant ainsi un héritage impérial et idéologique.Chausson François. De Didius Julianus aux Nummii Albini. In: Mélanges de l'École française de Rome. Antiquité, tome 112, n°2. 2000. Antiquité. pp. 843-879
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