133 research outputs found
Capitolo 1. Il fondo di sviluppo e coesione (FSC) e il processo di attuazione del federalismo fiscale.
No full textIl Piemonte e il PNRR. Una nuova fase della programmazione regionale?
No full textNext generation UE; PNRR; programmazione e pianificazione regionale, governo del territorio; rapporto Stato autonomie territoriali e local
Alberto Comparini, ‘”Actus” e “actio”: l'io come agente nei Canti di Leopardi (1818-1826)', Otto/Novecento, 40 (2016), 3, 177-91
No full textRecensione di A. Comparini, Actus e acti
"La mia cara Cecchina è baronessa": livelli stilistici e assetto drammaturgico ne “La buona figliuola” di Goldoni-Piccinni
No full textLo studio propone un'analisi drammaturgico-musicale della Buona figliuola di Goldoni-Piccinni dimostrando l'esistenza di una efficace e studiata strategia compositiva atta ad assecondare e valorizzare le indicazioni drammaturgiche allestite dell'autore del testo poetico.The study provides an analysis of the musical-dramatic daughter of Goldoni Good-Piccinni proving the existence of an effective and studied musical composition adapted to accommodate and enhance the signs of drama staged the author of the poetic text
Da Orfeo ad Anfione: mitizzazioni corelliane e il primato di Roma (ripensando la classicità di Corelli)
No full textLo studio interpreta la musica orchestrale di Corelli nel contesto del progetto pontificio (Clemente XI) di rilancio dell'imago Urbis tramite imponenti iniziative architettoniche. Detto «Anfione dei nostri tempi», Corelli venne inteso 'architetto' in quanto autore in grado di costruire con geometrica razionalità la composizione strumentale e, pertanto, di edificare monumenti sonori a maggior gloria di Roma e del papato. The study reconsiders Corelli's role within Pope Clement XI's project of renewal of the imago Urbis by means of great architectural initiatives. Named «Amphion of our times», Corelli was considered a musical architect since he was able to give geometric rationality to the instrumental composition and was then able to built musical monuments to the glory of Rome and of the Pope. Si richiede che il prodotto sia sottoposto a peer review e non a valutazione con criteri bibliometrici.The study interprets the orchestral music of Corelli in the context of the papal project (Clement XI) recovery of the imago Urbis by imposing architectural initiatives. Said, "Amphion of our times," Corelli was intended 'architect' as the author can build with geometric rationality and instrumental composition, therefore, to build monuments to sound greater glory of Rome and the papacy. The study reconsiders Corelli's Role Within Pope Clement XI's project of renewal of the Imago Urbis by means of great architectural Initiatives. Named "Amphion of our times," Corelli was Considered a musical architect since he was Able to give to the geometric rationality and instrumental composition was then built Able to musical monuments to the glory of Rome and of the Pope. It requires that the product is subjected to peer review and assessment with bibliometric criteria
Study on mupirocin treatment in cutaneous lupus erythematosus: comment on the article by Abernathy-Close et al
No full textAbernathy-Close et al1 provide a valuable contribution to theunderstanding of therapy for cutaneous lupus erythematosus(CLE) through their proof-of-concept study examining the effectsof mupirocin, a topical antibiotic, on inflammatory pathways withinCLE lesions. Their data indicate a correlation between reducedStaphylococcus aureus bacterial load and a subsequent declinein local inflammation, as well as decreased expression of inflam-matory genes, .particularly those related to type I interferon (IFN)signaling. These findings highlight the pivotal role of the skinmicrobiome in influencing immune responses and advancingtreatment options for lupus-associated skin lesion
Symplectic local time-stepping in non-dissipative DGTD methods applied to wave propagation problems
No full textInternational audienc
How to Think of Intersection Types as Cartesian Products
No full textAbstractIn their paper “Intersection types and lambda definability” [Bucciarelli, A., Piperno, A., Salvo I., Intersection types and lambda definability, MSCS03, 13 (1), pp. 15–53, (2003)] Bucciarelli, Piperno, and Salvo give a mapping of the strongly normalizable untyped terms into the simply typed terms via the assignment of intersection types. Here we shall both generalize their result and provide a converse. We shall do this by retracting untyped terms with surjective pairing onto untyped terms without pairing by using a special variant of Stovring's notion [Støvring, K., Extending the extensional lambda calculus with surjective pairing is conservative, LMCS 2, pp. 1–14] of a symmetric term. The symmetric ones which have simple types with Cartesian products are precisely the ones which retract onto (eta expansions of) strongly normalizable untyped terms. The intersection types of the strongly normalizable terms are related to the simple types with products in that we just replace ∧ by Cartesian product and vice versa
The prognostic value of fMRI and H1-MRS spectroscopy in the study of patients in vegetative state.
No full textINTRODUCTION
In our experience, tools as fMRI and H1-MRI spectroscopy may add valuable information to the standard clinical assessment and prognosis in patients characterized vegetative state (VS), minimally conscious state (MCS) and severe disability (SD). Such information could have an impact on clinical decision making, may guide therapeutic options and could be used to stream rehabilitation programs.
AIM
We used fMRI to study both the presence and the degree of functional activation in VS and MCS and SD patients and tried to discover any possible changes in the markers of neuronal turn-over by H1-MRI spectroscopy.
MATERIALS & METHODS
We enrolled 24 patients (age comprised between 17 and 58) with outcome of comas: 20 of them had polytrauma outcomes, 3 of them had cerebral anoxia, 1 of them had encephalitis outcome. Each patient underwent morphological, fMRI and H1-MRS spectroscopy analysis. A 3T Signa Excite system and an 8 channel phased array coil were used to acquire morphological sequences fMRI and H1-MRS spectroscopy.
fMRI. Functional (Axial Single Shot, SS, EchoPlanar Image, EPI, Gradient Echo, GE), and morphological (isovolumetric SPoiled GRass - Inversion Recovery, SPGR-IR) sequences were acquired. We used a block paradigm of the kind: 30 s stimulus vs 30 s rest, for a total length of 5 min. Three different paradigms were applied: 1) in the stimulus phase, the patient heard the voice of a relative telling an emotionally significant episode, vs silence; 2) in the stimulus phase, the patient heard the same voice telling the same episode as in point 1), but the voice was played in the reverse order, vs silence; 3) in the stimulus phase, the patient heard the same voice as in 1), whereas in the rest phase the patient heard the same reverse voice as in point 2). fMRI analysis was performed off-line by using BrainWave GE proprietary software. Briefly, the processing of this software is semi-automatic and consists in segmentation and coregistration of the morphologic sequence to the fMRI sequence, after the appropriate corrections (motion correction, smoothing, etc.). The final parametric maps were calculated at a p<0.01 threshold and superimposed to the morphological coregistered segmented images.
Spectroscopy (Single voxel, Point-Resolved Spectroscopy Sequence, PRESS). We analyzed the following metabolite ratios: mI/Cr, Cho/Cr, NAA/Cr, NAA/Cho. Resulting spectra were processed by SAGE Software (Spectral Analysis, GE Medical System). Particularly, we focused on NAA/Cho ratio, because it has been showed that a reduction of this ratio has a negative prognostic value. We compared the NAA/Cho values obtained in VS/MCS/SD patients with the corresponding values obtained in 16 healthy volunteers (age comprised between 25 and 57), by placing the voxel in the left frontal white matter. Normal NAA/Cho reference values were in the range of 2.0 ± 0.3.
RESULTS
fMRI. When present, activations were located in the temporal lobes, mono or bilaterally depending of the characteristics of the cerebral lesions. Patients were divided in two groups: the ones showing clear-cut activations (15 patients, 65%) and the ones showing no activation (8 patients, 35%).
H1-MRS spectroscopy. Considering the NAA/Cho ratios, we divided patients in three groups: NAA/Cho ratios ≤ 1 (undoubtedly pathologic), NAA/Cho ratios in the range between 1.1 and 1.6 (moderately pathologic), and NAA/Cho ratios ≥ 1.7 (normal). Considering the NAA/Cho ratio of the 15 activated patients, five (33%) of them showed a NAA/Cho ratio ≤ 1, six (40%) of them showed a NAA/Cho ratio in the range between 1.1 and 1.6, and four (27%) of them showed a NAA/ Cho ratio ≥ 1.7. Considering the NAA/Cho ratio of the 8 patients showing no activation, three (38%) of them showed a NAA/Cho ratio ≤ 1, five (62%) of them showed a NAA/Cho ratio in the range between 1.1 and 1.6, and no one (0%) showed a NAA/Cho ratio ≥ 1.7.
DISCUSSION
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