92 research outputs found
Impiego di silice mesoporosa SBA-15 come supporto per l’immobilizzazione di lipasi da Rhizopus Oryzae
Paola Imperatore, Emanuele Leonardi, L’era della giustizia climatica. Prospettive politiche per una transizione ecologica dal basso. Napoli-Salerno, Orthotes Editrice, 2023.
Francesco Chiodelli, Cemento armato. La politica dell'illegalità nelle città italiane (Giovanni Laino) – Maurilio Pirone (a cura di), Ultimo Miglio. Lavoro di piattaforma e conflitti urbani (Laura Eccher) – Leslie Kern, La gentrificazione è inevitabile e altre bugie (Teresa Graziano) – Giovanni Semi, Manuale per una gentrificazione carina (Teresa Graziano) – Paola Imperatore, Emanuele Leonardi, L'era della giustizia climatica. Prospettive politiche per una transizione ecologica dal basso (Giorgia Scognamiglio) – Maria Chiara Giorda, La Chiesa ortodossa romena in Italia. Per una geografia storico-religiosa (Alberto Vanolo) 
Neuroendocrine mechanism in pregnancy and parturition
The complex mechanisms controlling human parturition involves mother, fetus, and placenta, and stress is a key element activating a series of physiological adaptive responses. Preterm birth is a clinical syndrome that shares several characteristics with term birth. A major role for the neuroendocrine mechanisms has been proposed, and placenta/membranes are sources for neurohormones and peptides. Oxytocin (OT) is the neurohormone whose major target is uterine contractility and placenta represents a novel source that contributes to the mechanisms of parturition. The CRH/urocortin (Ucn) family is another important neuroendocrine pathway involved in term and preterm birth. The CRH/Ucn family consists of four ligands: CRH, Ucn, Ucn2, and Ucn3. These peptides have a pleyotropic function and are expressed by human placenta and fetal membranes. Uterine contractility, blood vessel tone, and immune function are influenced by CRH/Ucns during pregnancy and undergo major changes at parturition. Among the others, neurohormones, relaxin, parathyroid hormone-related protein, opioids, neurosteroids, and monoamines are expressed and secreted from placental tissues at parturition. Preterm birth is the consequence of a premature and sustained activation of endocrine and immune responses. A preterm birth evidence for a premature activation of OT secretion as well as increased maternal plasma CRH levels suggests a pathogenic role of these neurohormones. A decrease of maternal serum CRH-binding protein is a concurrent event. At midgestation, placental hypersecretion of CRH or Ucn has been proposed as a predictive marker of subsequent preterm delivery. While placenta represents the major source for CRH, fetus abundantly secretes Ucn and adrenal dehydroepiandrosterone in women with preterm birth. The relevant role of neuroendocrine mechanisms in preterm birth is sustained by basic and clinic implication
Mesial side ovarian incision for laparoscopic dermoid cystectomy: A safe and ovarian tissue-preserving technique
Hypoxia and preeclampsia: increased expressions of urocortin 2 and urocortin 3
Objective: Urocortin 2 (Ucn2) and urocortin 3 (Ucn3) are new members of the corticotrophin-releasing hormone (CRH) family of peptides expressed and localized in human placenta. In the current study, we aimed to asses whether hypoxia affects placental Ucn2/Ucn3 messenger RNA (mRNA) expression and protein localization in physiological or pathological hypoxia and to evaluate whether the effect is modulated by the hypoxia-inducible factor 1α (HIF-1α). Methods: Early first-trimester placental specimens from elective termination of pregnancy were used for villous explants and term placental tissue were used for primary cell cultures. The samples were incubated under different oxygen conditions; parallel sets exposed to hypoxia re-oxygenation (HR). Dimethyloxalylglycine (DMOG), an HIF-1α stabilizer, was used to mimic the effects of hypoxia in villous explants. Real-time polymerase chain reaction (PCR) and immunohystochemistry were performed on early pregnancy and preeclamptic (PE) placentae. mRNA levels were measured on villous explants and cell cultures incubated under different oxygen and reagent conditions. Results: Both Ucn2 and Ucn3 mRNA expression was significantly higher at 6 to 9 weeks of gestation than 10 to 12 wks and in primary trophoblast cell cultures and explants exposed to low O2 tension (3%) compared to 20% O 2. Strong Ucn2/Ucn3 immunoreactivity was present in trophoblast villi from 6 weeks placentae. Ucn2 immunostaining was stronger in early PE (E-PE) samples relative to controls whereas Ucn3 showed stronger immunoreactivity in late-PE (L-PE) placentae. Only Ucn2 transcript levels increased in HR explants. Ucn2 and Ucn3 expression by first-trimester explants was significantly greater in the presence of DMOG. All PE placentae expressed significantly higher Ucn2 and Ucn3 mRNA compared to controls. Discussion: Placental Ucn2 and Ucn3 expression is sensitive to O2 tensions and mediated by HIF-1α. During early pregnancy, Ucn2/Ucn3 may influence trophoblast proliferation and establishment of pregnancy. In PE placentae, the increased expression of both peptides may reflect a response to the oxidative stress. © The Author(s) 2010
Punching shear behavior of lightweight fiber reinforced concrete slabs
The ultimate behavior of thin reinforced concrete structures, such as slabs, can be governed by punching due to point loads. This premature brittle failure mode can occur in bridge deck slabs, often subjected to severe conditions of loads concentrated in small areas, and characterized by a reduced thickness. In this kind of structures, a proper punching reinforcement is not applicable, but the local and global behavior can be improved by the addition of short fibers. Three full-scale slabs, simulating bridge decks, were tested in the Laboratory of the University of Rome Tor Vergata, to investigate the effect of lightweight fiber reinforced material on the punching shear resistance. Furthermore, ashes coming from the combustion of Municipal Solid Waste (MSW), with pozzolanic reaction, were added to the concrete mix. The obtained results are presented, discussed and compared with the MC2010 provisions
Drawing on a dream
DRAWING OUT 2012Paper Title: Drawing on a Dream Author: Lynn Imperatore Affiliations:•PhD Researcher/University of the West of England/Department of Art & Design, ACE •Co-Chair, HATCH Research Project,PLaCE Research Centre, UWE•Research Student Member, PLaCE Research Centre, UWE AbstractThis paper considers possible entries into precincts of imagination and imaginative activity - through a consideration of drawing practice as method for thinking about and around alterations of and away from ordinary consciousness, particularly sleep. Drawing interrogates assumed beliefs - apparitions of unassailable reality - by distilling these into abstracted component parts. The observant draughtsman cultivates an ability to withhold aspects of cognition and recognition from perception, therefore purposely refusing to find conclusion in preconception. New views, re-presentations, accidental revelation (from the unconscious and the unintentional) lead to novel an expanded knowledges. Drawing and sleep engage commonality as practices or habits that provide opportunity to discern qualities of the mysterious embedded within the ordinary. Central to this study is a shared visual language and sleight-of-hand in drawing and dreaming - imaginative activities that can generate (impossible) imagery, and lead us to a richer apprehension of interior life. Drawing and dreaming are magical manifestations - with hints of broader imaginative territories just over the edge of the page or slipping off into slumber. Work of select contemporary artists - including William Kentridge, Antonio Lopez-Garcia, Louise Bourgeois - are located and viewed in their practice relationships to creative predecessors of the devotional heyday of the European Renaissance. Artists - particularly in acts of drawing - still strive to give visual depictions of that which we know - but can never actually see. Conference & Publication ThemeDrawing and Notation. Drawing as a sometimes intuitive other times driven by convention means of mapping appearance and movement . With special reference to innovative methods of notationDrawing: recording and discovery. Drawing as a speculative activity and means of transferring informatio
Un antieroe dai molti volti. Giuliano a Bisanzio come Apostata, scrittore, imperatore e in una particolare interpretazione «ratzingeriana» dello storico Sozomeno
Giuliano l’Apostata, l’ultimo imperatore pagano, è oggetto a Bisanzio di un’aspra
condanna che diventa quasi topica. Ma Giuliano è anche l’autore di opere della letteratura
greca, che furono in buona parte trasmesse dai copisti bizantini, e inoltre voci più o
meno favorevoli a Giuliano, per quanto rare, non mancarono del tutto. Anche Sozomeno,
storico ortodosso del quinto secolo che lo condanna per la sua politica anticristiana,
evita dimostrazioni di astiosa ostilità. Egli anzi sceglie di esaltare il cristianesimo e la
sua origine divina dimostrando che anche un nemico abile e di valore come Giuliano è
impotente. Il suo atteggiamento di rispetto verso la figura dell’ultimo imperatore pagano
è paragonabile a quello di altri autori cristiani di varie epoche, come Chateaubriand e
Benedetto XVI.The harsh condemnation in Byzantium of Julian the Apostate, the last pagan emperor,
is almost a common place. But Julian was the author of works of Greek literature, most
of which were transcribed by Byzantine copyists, and other voices more or less in his
favor, even if rare, could still be heard. Sozomenos, too, an orthodox historian of the fifth
century, condemns him for his anti-Christian politics, but does not show open hostility.
He chooses to glorify Christendom and its divine origin by showing that even an intelligent
and worthy enemy like Julian was impotent against it. Sozomenos has respect for
Julian, as have other Christian writers of more recent times, for example Chateaubriand
and pope Benedict XVI
Fra realtà e mistificazione: il potere del Principe a Roma e nelle periferie dell’impero
Lo scopo di questo contributo è di discutere le realtà del potere imperiale e, più specificamente, l'estensione dei poteri dell'imperatore in relazione alle élites locali in Italia e nelle province. Anche gli imperatori dovevano riconoscere il potere esercitato nei rispettivi contesti civici dai primi cittadini delle periferie dell'impero. Come si vedrà, sebbene la propaganda imperiale si proponesse di promuovere l'immagine di un imperatore onnipotente, è nelle periferie dell'impero che si può apprezzare la reale estensione delle prerogative e dei poteri dell'autorità imperiale.The purpose of this contribution is to discuss the realities of imperial power and, more specifically, the extent of the emperor's powers in relation to local elites in Italy and the provinces. Even emperors had to recognize the power exercised in their own civic contexts by the first citizens of the empire's peripheries. As will be seen, although imperial propaganda was intended to promote the image of an all-powerful emperor, it is in the peripheries of the empire that the actual extent of imperial authority can be effectively recognized
Il Macrino di Ausonio e del Liber Memorialis
Questo elaborato affronta il problema della datazione e dei destinatari del Liber Memorialis di Lucio Ampelio, con lo scopo di stabilire se l'opera possa essere rivolta a Opilio Macrino, imperatore romano del 3. secolo
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