28 research outputs found
COMPLEMENTARY EFFORTS OF GOVERNMENTAL AND NON-GOVERNMENTAL ORGANISATIONS IN THE REHABILITATION OF THE DISABLED
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The colour selection of distant galaxies in the UKIDSS Ultra Deep Survey Early Data Release
No full textWe investigate colour selection techniques for high-redshift galaxies in the UKIRT Infrared Deep Sky Survey (UKIDSS) Ultra Deep Survey Early Data Release (UDS EDR). Combined with very deep Subaru optical photometry, the depth (KAB= 22.5) and area (0.62 deg2) of the UDS EDR allow us to investigate optical/near-infrared selection using a large sample of over 30 000 objects. By using the B−z′, z′−K colour–colour diagram (the BzK technique) we identify over 7500 candidate galaxies at z > 1.4, which can be further separated into passive and star-forming systems (pBzKs and sBzKs respectively). Our unique sample allows us to identify a new feature not previously seen in BzK diagrams, consistent with the passively evolving track of early-type galaxies at z 1 galaxies over a narrow redshift range
The aqueous extract of<i>Ocimum gratissimum</i>leaves ameliorates acetic acid-induced colitis via improving antioxidant status and hematological parameters in male Wistar rats
No full textKolaviron attenuates diclofenac-induced nephrotoxicity in male Wistar rats
No full textThe beneficial effects of kolaviron, a natural biflavonoid from the seeds of Garcinia kola, have been attributed to its antioxidant and anti-inflammatory activities. This study was designed to investigate the renoprotective effect of kolaviron in rat model of diclofenac (DFC)-induced acute renal failure. Thirty-five male Wistar rats were divided into seven groups of five rats each as follows: a control group that received propylene glycol orally and treatment groups that received diclofenac, diclofenac followed by kolaviron at three different doses and kolaviron only. Diclofenac treated rats showed sluggishness, illness and anorexia. Their urine contained appreciable protein, glucose and ketone bodies. Histopathological examination of their kidneys revealed profound acute tubular necrosis. Diclofenac treatment significantly increased levels of plasma creatinine, urea, sodium, chloride, potassium ions, and increased renal tissue activities of superoxide dismutase, catalase, levels of malondialdehyde and hydrogen peroxide. Fractional excretion of sodium and potassium and renal tissue levels of reduced glutathione and prostaglandin E2 (PGE2) decreased significantly in DFC treated groups. However, kolaviron administration significantly reduced toxic effect of DFC on PGE2 release, plasma levels of creatinine, urea, glucose, and electrolytes and significantly attenuated renal tubular and oxidative damages. Furthermore, the effects of DFC administration on food consumption, water intake, urine output and urine protein, glucose, ketone bodies and electrolytes, were significantly attenuated in animals treated with kolaviron. The results suggested that kolaviron ameliorated DFC-induced kidney injury in Wistar rats by decreasing renal oxidative damage and restoration of renal PGE2 release back to the basal levels.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
.) Leaf on Aspirin-Induced Gastric Ulceration and Oxidative Mucosal Damage in a Rat Model of Gastric Injury
No full textPolyphenol-rich extract of Ocimum gratissimum leaves ameliorates colitis via attenuating colonic mucosa injury and regulating pro-inflammatory cytokines production and oxidative stress
No full textPrevalence, predictors and effects of shift work sleep disorder among nurses in a Nigerian teaching hospital
No full textAbstract Background This study evaluated the prevalence, predictors and effects of Shift Work Sleep Disorder (SWSD) among nurses in a Nigerian teaching hospital. Methods Eighty-eight nurses (44 each from the pool of shift and non-shift nurses), who emerged by simple random sampling, participated in the study. Socio-demographic data and health complaints were obtained with questionnaires. Each participant was assessed with Epworth sleepiness scale (ESS), insomnia severity index (ISI) and sleep log, while SWSD cases were ascertained by applying the International Classification of Sleep Disorders (ICSD-2) criteria. Body mass index, blood pressure, body temperature and salivary cortisol levels were also determined. Results Generally, results showed that the shift group; comprising of shift nurses, recorded higher values of biophysical profiles and more health complaints than the non-shift group (control); comprising of non-shift nurses. Also, 19 (43.2%) of the shift nurses fulfilled the criteria for SWSD, on this basis, the shift group was divided into two: SWSD (n = 19) and No SWSD (n = 25). And within the shift group, the SWSD group had higher systolic (p = 0.014), diastolic (p = 0.012), and mean arterial (p = 0.009) blood pressures; they also recorded higher temperature (p = 0.001), higher salivary cortisol levels (p = 0.027) and more health complaints. Conclusion The results of this study indicate that rotating shift work among nurses is associated with increased level of health complaints and physiologic indices of stress as well as sleep impairment
Protective Effects of Methanol Extract of (.) Leaf on Aspirin-Induced Gastric Ulceration and Oxidative Mucosal Damage in a Rat Model of Gastric Injury
No full textThis study investigated the quantitative polyphenolic constituents and gastroprotective effects of methanol extract of Vernonia amygdalina leaf (MEVA) against aspirin-induced gastric ulcer in rats. Ulceration was induced by 3 days’ oral administration of aspirin (150 mg/kg body weight). Wistar rats were pretreated with cimetidine (reference drug) at a dose of 100 mg/kg body weight and MEVA at 200, 300, and 400 mg/kg body weight once daily for 28 days prior to ulcer induction. At the end of the experiment, gastric secretions, antioxidant status, and histopathological alteration were evaluated. We observed that the significantly increased ulcer index, gastric volume, free and total acidity, malondialdehyde level, and pepsin activity were effectively reduced following treatment with 200 and 300 mg/kg MEVA. The extract also markedly attenuated the reduced activity of superoxide dismutase and reduced glutathione level as well as pH and mucin content in the ulcerated rats. Administration of the extract also significantly attenuates necrosis of the stomach tissue of the ulcerated rats. The results suggested that the MEVA leaf, preferably at 200 and 300 mg/kg body weight, ameliorated aspirin-induced gastric ulceration via antioxidative and H 2 receptor antagonist
Prevalence, predictors and effects of shift work sleep disorder among nurses in a Nigerian teaching hospital
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