248 research outputs found
Nerve conduction study and Fas mediated apoptosis of nerve cells in peripheral neuropathy in type 2 diabetes
AbstractApoptosis may play a crucial role in the pathogenesis of late diabetic neuropathy. We determine the role of Fas mediated apoptosis in the aetiopathogenesis of diabetic neuropathy, by measurement of apoptosis markers, induction of apoptosis by Fas and/or serum and correlate the level of soluble Fas (marker of apoptosis) with the nerve conduction study. Furthermore, we elucidate the role of apoptosis inhibition in prevention of diabetic neuropathy by the Fas blocker (ZB4).There was significant increase in the sFas serum level in diabetics with neuropathy as compared to the controls and diabetic patients without neuropathy (p<0.005). All parameters of the motor median nerve conduction study showed significant correlation with the serum sFas levels, especially the nerve conduction velocity (r=−0.60, p<0.01). Cells treated with the serum of diabetic patients with neuropathy showed significantly higher percentages of early and late apoptosis (p<0.05) compared to the negative control. A 500ng/mL Fas blocker (ZB4), antagonistic anti-Fas antibody caused significantly lower levels of early and late apoptosis (p<0.025) compared to serum of diabetic patients with neuropathy treatment.In conclusion, Fas-mediated apoptosis of the neuronal cell line is responsible for the degradation of the neurons in patients with diabetic neuropathy and provides evidence for the involvement of the receptor pathway in Fas-mediated apoptosis of these cells. Thus, targeting and inhibiting Fas receptor offers an option for diabetic neuropathy therapy
Finite element analysis of CFRP strengthened steel hollow sections under tension
This paper presents a nonlinear finite element (FE) model for the analysis of very high strength (VHS) steel hollow sections wrapped by high modulus carbon fibre rein forced polymer (CFRP) sheets. The bond strength of CFRP wrapped VHS circular steel hollow section under tension is investigated using the FE model. The three dimensional FE model by Nonlinear static analysis has been carried out by Strand 7 finite element software. The model is validated by the experimental data obtained from Fawzia et al [1]. A detail parametric study has been performed to examine the effect of number of CFRP layers, different diameters of VHS steel tube and different bond lengths of CFRP sheet. The analytical model developed by Fawzia et al. [1] has been used to determine the load carrying capacity of different diameters of CFRP strengthened VHS steel tube by using the capacity from each layer of CFRP sheet. The results from FE model have found in reasonable agreement with the analytical model developed by Fawzia et al [1]. This validation was necessary because the analytical model by Fawzia et al [1] was developed by using only one diameter of VHS steel tube and fixed (five) number of CFRP layers. It can be concluded that the developed analytical model is valid for CFRP strengthened VHS steel tubes with diameter range of 38mm to 100mm and CFRP layer range of 3 to 5 layers. Based on the results it can also be concluded that the effective bond length is consistent for different diameters of steel tubes and different layers of CFRP. Three layers of CFRP is considered most effective wrapping scheme due to the cost effectiveness. Finally the distribution of longitudinal and hoop stress has been determined by the finite element model for different diameters of CFRP strengthened VHS steel tube
Interview with Fawzia Al-Bakry
مقابلة مع الدكتورة المصرية فوزية البكري رئيسه قسم العلاج الطبيعى بمؤسسة يوم المستشفيات لتأهيل المعوقين تشرح فيها دور العلاج الطبيعى والامراض التي يدخل فيها العلاج الطبيعي ويأتي بنتائج ناجحة. قام بالمقابلة إبراهيم عابدين.An interview with the Egyptian Dr. Fawzia Al-Bakry, head of the physiotherapy department at the Hospitals Day Foundation for the Rehabilitation of the Disabled, in which she explains the role of physiotherapy and the diseases in which physiotherapy is involved and brings successful results. The interview was conducted by Ibrahim Abdeen
Interview with Fawzia Mahran
لقاء مع الكاتبة الصحفية فوزية مهران للتحدث على أشياء قرأتها، سمعتها، و رأتها في برنامج بهذا الإسم. أجرى هذا اللقاء ميرفت الديربي وسعد عطية.An Interview with Egyptian journalist and writer Fawzia Mahran about things she recently read, listened to and saw in a show of the same name. Interview conducted by Mervat Al-Derby and Saad Attia
A Review on Children's Literature in Afghanistan
Children\u27s and adolescent literature have a long-life span in the history of mankind and is considered one of the major parts of the literature in every nation. Children\u27s and teenagers\u27 literature received worldwide attention from the 17th century AD. In the 18th century, scientists drew the attention of educators and people to children\u27s literature by research publishing works. In our rich classical literature, there is not much research done on children\u27s literature. However, various works have been done for children in recent years. The first children\u27s magazine in Afghanistan was Siraj-ul-Atfal, which was published continuously with Siraj-ul-Akhbar. This magazine was mostly educational and entertaining, and most of its content was general information, scientific topics, religious and moral content in the form of poems and stories. After publishing the children literature in Siraj-ul-Akhbar, other publications also started about children\u27s literature in Afghanistan, such as children’s friendship, youngs friendship, and children\u27s voice. Some writers have also done research on children\u27s literature in Afghanistan, such as Abdul Qayyum Qoyim, Mohammad Hossein Yamin, Paizi Hanafi, Habibullah Rafi, Dr Asadullah Khitfi, Seyyed Davoud Zahdi, Pouya Faryabi, Asif Behand, Raziq Varin, and Osman Najand
The Role of Mother Tongue in Education
Mother tongue plays a significant role in education. It is a fundamental tool for facilitating learning. Without the use of the mother tongue, understanding educational concepts becomes impossible for students whose mother tongue differs from the official language. The mother tongue holds great value and importance in the educational process. By using their mother tongue, students gain the opportunity to understand lesson concepts better, feel more comfortable in the classroom, and solve their academic problems more easily. The mother tongue validates students\u27 individual experiences and creates a conducive environment for them to express their thoughts, ideas, feelings, experiences, theories, and learnings without anxiety. Moreover, the mother tongue is essential in preserving and promoting the culture and identity of individuals. Incorporating the mother tongue into educational systems integrates culture with the curriculum, fostering a positive attitude among students toward the societal culture
Fawzia al-Ashmawi-Abouzeid, La Femme et l’Égypte moderne dans l’œuvre de Naguib Maḥfūẓ (1939-1967), préface de Nada Tomiche. Labor et Fides, Publications orientalistes de France, Genève, 1985
Mallet Dominique. Fawzia al-Ashmawi-Abouzeid, La Femme et l’Égypte moderne dans l’œuvre de Naguib Maḥfūẓ (1939-1967), préface de Nada Tomiche. Labor et Fides, Publications orientalistes de France, Genève, 1985. In: Bulletin critique des annales islamologiques, n°4, 1987. pp. 29-32
Assessing Physiological and Psychological Factors Contributing to Stress among Medical Students: Implications for Health
Background: Physiological responses to stress disturb internal homeostasis, leading to serious health consequences. Medical students experience high stress levels that should be managed promptly to prevent stress-related impacts on students’ health and education. Aim: This study aims to identify the relationship between stress factors, general health, and academic performance. Methods: This study recruited 421 medical students of all academic years. Participants completed an online survey assessing stress levels using a validated 10-item Perceived Stress Scale. Stress was also compared with students’ health and academic performance. Results: We found that 93.6% of our sample experienced moderate to severe stress, and 31% reported increased stress due to the coronavirus disease (COVID-19) pandemic. Except for internship students, stress significantly decreases as students progress each academic year (p < 0.05). Students with higher GPAs and with comorbidities are more stressed. Comorbidities were primarily reported in students in their final years of education with a 4% lower GPA than healthy students. Although we had three stress-related themes (general, academic, and pandemic), students’ perceptions of stress factors were primarily academically related. Conclusions: Students experience high stress levels in their final educational years, which might increase the risk of health issues and low academic performance. It is essential to innovate stress-coping strategies specially designed for medical students and mandatorily provided by all medical colleges and to educate students on the effects of stress on their health
Bond characteristics between CFRP and steel plates in double strap joints
This paper describes a series of double strap shear tests loaded in tension to investigate the bond between CFRP sheets and steel plates. Both normal modulus (240 GPa) and high modulus (640 GPa) CFRPs were used in the test program. Strain gauges were mounted to capture the strain distribution along the CFRP length. Different failure modes were observed for joints with normal modulus CFRP and those with high modulus CFRP. The strain distribution along the CFRP length was found to be similar for the two cases. A shorter effective bond length was obtained for joints with high modulus CFRP whereas larger ultimate load carrying capacity can be achieved for joints with normal modulus CFRP when the bond length is long enough. The Hart-Smith Model was modified to predict the effective bond length and ultimate load carrying capacity of joints between the normal modulus CFRP and steel plates. The Multilayer Distribution Model developed by the authors was modified to predict the load carrying capacity of joints between the high modulus CFRP and steel plates. The predicted values agreed well with experimental ones
La femme et l'Égypte moderne dans l'œuvre de Naguīb Maḥfūẓ : 1939-1967 / Fawzia A. al Ashmawi-Abouzeid ; préf. de Nada Tomiche
Collection : Collection Arabiyya ; 7Collection : Collection Arabiyya ; 7Contient une table des matièresAvec mode text
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