3 research outputs found
Association Between Periodontitis and COVID-19
No full textPurpose of ReviewPeriodontitis has been linked to various systemic diseases and conditions. Given their shared comorbidities, extensive research has been carried out to explore the link between periodontitis and COVID-19.Recent FindingsA growing body of evidence suggests that periodontitis could increase the risk of COVID-19 infection and its complications. It has been suggested that the association between the two diseases could be due to immunological, coagulation, genetic, and microbiological reasons. The effect of periodontitis on the immune system could increase the expression of receptors used by SARS-CoV2 to infect cells (transmembrane protease, serine 2 [TMPRSS2], and angiotensin-converting enzyme 2 [ACE2]) and prime the immune system to an exacerbated immune reaction against the virus. Moreover, there is evidence indicating that periodontitis could also increase the risk of COVID-19 complications by altering the coagulation pathways, and periodontal pathogens were identified in the respiratory system of patients suffering from severe COVID-19. In addition, it was also found that patients suffering from both diseases share some genetic similarities, suggesting that both diseases could be linked through common genetic pathways.SummaryIn this review, we discuss the above-mentioned associations and make the case for the prevention and treatment of periodontitis to avoid SARS-CoV-2 infection and complications.Other InformationPublished in: Current Oral Health ReportsLicense: https://creativecommons.org/licenses/by/4.0See article on publisher's website: https://dx.doi.org/10.1007/s40496-023-00361-0</p
Periodontal precision: diagnostic skills and confidence of dentists in Asian countries in applying the 2017 EFP/AAP periodontal disease classification- a cross-sectional pilot study
No full textBackground: The classification of periodontal disease published in 2017 by the European Federation of Periodontology (EFP) and American Academy of Periodontology (AAP), provides a framework for diagnosis and treatment. The aim of this study was to evaluate the diagnostic skills and self-perceived confidence of dentists and dental students based in Asian countries in the use of this classification. Methods: A cross-sectional analytic study design was employed. An online questionnaire encompassing four periodontitis cases was used for data collection. A total of 500 participants were invited to provide a diagnosis and rate their confidence for each case. Results: Responses were provided by 312 participants completed including 192 females and 120 males. Analysis of variance (ANOVA) showed a statistically significant difference in accuracy across cases by Professional Role (F (9,924) = 2.304, p = 0.005), and an overall difference on accuracy by Professional Role (F (1,308) = 2.304, p = 0.012). The diagnostic accuracy mean was highest for periodontics specialists (57.81 ± 49.78) followed by general dentists (50.00 ± 50.31), other dental specialists (45.00 ± 50.06); and dental students (25.00 ± 43.55). A statistically significant difference in confidence was noted across Age Groups, Gender, and Roles (F(1,291) = 6.356, p \u3c 0.001; F(1,293) = 13.747, p \u3c 0.001; F(1,291) = 8.731, p \u3c 0.001 respectively). There was no statistically significant effect on confidence ratings by any interaction between Location and Case. Conclusion: The study shows the diagnostic accuracy and confidence was highest amongst periodontology specialists followed by general dentists and undergraduate students. Overall the participants showed suboptimal diagnostic accuracy and confidence
Bioactive hybrid membrane-based cellulose acetate/bioactive glass/hydroxyapatite/carbon nanotubes nanocomposite for dental applications
No full textThe present work aimed to fabricate a set of hybrid bioactive membrane in the form of bio-nanocomposite films for dental applications using the casting dissolution procedures. The formulation of the targeted materials was consisting of cellulose acetate/bioactive glass/hydroxyapatite/carbon nanotubes with a general abbreviation CA-HAP-BG-SWCNTs. The nanocomposites were characterized using XRD, FTIR, SEM-EDX and Raman spectroscopy. XRD, FTIR and SEM characters confirm the nanocomposites formation with good compatibility. The fabricated materials had a semi crystalline structure. The mechanical and thermal properties, as well as contact angle and bioactivity of the fabricated nanocomposites were investigated. The SEM images for showed beehive-like architectures with a thicker frame for the second material. All fabricated materials showed good thermal behaviors. Furthermore, the agar diffusion antimicrobial study showed that the prepared nanocomposites do not exhibit an antibacterial activity against five pathogenic bacterial strains. Additionally, cytotoxicity of a dental nanocomposite filling agent was evaluated. Vero normal cells were incubated with test materials for 72h at 37 °C and 5% CO2. Cell viability was detected using a SRB assay. All nanocomposites were mildly to non-cytotoxic to Vero cells at high concentration in contrast to the inhibitory effect of doxorubicin which was added at 10-fold lower concertation than the nanocomposites. Hence, the proposed nanocomposite is promising candidates for dental applications.The researchers would like to acknowledge Deanship of Scientific Research, Taif University for funding this work
