1,110 research outputs found

    The problem of achieving high second-order nonlinearities in glasses: The role of electric conductivity in poling of high index glasses

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    Efficient thermal poling of electronically conducting glass is prevented by the inherent difficulty to record a large electrostatic field within such glasses. To overcome this limitation, a waveguide/substrate configuration has been proposed, in which the glass for poling was deposited as a film of appropriate thickness on a substrate chosen for its higher ionic conductivity. Owing to this configuration, the poling voltage drops entirely across the glass film, allowing high electrostatic field to be recorded in spite of the high electronic conductivity of the glass. The proposed method was demonstrated here in the case of bismuth-zinc-borate glasses, which possess high potential for poling because of their high intrinsic χ(3). A four-fold enhancement of χ(2) compared to bulk glass, from ~ 0.5 to ~ 2 pm/V, is demonstrated. It is also shown that the χ(2) values obtained are the highest sustainable by the glass limited by the onset of nonlinear conductivity. The waveguide/substrate configuration intrinsically allows obtaining perfect overlap of the poling induced second-order nonlinearity with the guiding region of the waveguide. An equivalent RC-circuit model describing the poled glass reveals that the value of the poling-induced second-order nonlinearity is strongly dependent on the ratio β between ionic and electronic conductivity. The most promising glass systems for poling are found to be the ones displaying the highest product χ(3)β. This work is performed on bismuth-zinc-borate heavy metal oxide glasses but the waveguide/substrate configuration proposed here is likely to be equally successful in enhancing the second-order nonlinearity in high χ(3) electronic conducting glasses such as for example telluride and chalcogenide glasses

    Structural Geology of the Cariboo Gold Mining District, East-Central British Columbia:

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    L.C. Struik.Memoir (Geological Survey of Canada) ; 421

    Thermal cycling and ageing of a glass-ceramic sealant for planar SOFCs

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    Thermal cycling and thermal ageing tests were performed on Crofer22APU/glass-ceramic/ Anode-Supported-Electrolyte (ASE) joined samples in air at the SOFC operating temperature of 800 C. The Crofer22APU had been polished and preoxidised at 900 C for 2 h. The diffusion behaviour at the two interfaces was examined and revealed slight diffusion of chromium and manganese from Crofer22APU into the glass-ceramic. No interactions, failure or crack formation were observed at the Crofer22APU/glass-ceramic interface and between the glass-ceramic and YSZ

    Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution

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    Non-steroidal anti-inflammatory drugs (NSAIDs) contribute to gastrointestinal ulcer formation by inhibiting epithelial cell migration and mucosal restitution; however, the drug-affected signaling pathways are poorly defined. We investigated whether NSAID inhibition of intestinal epithelial migration is associated with depletion of intracellular polyamines, depolarization of membrane potential (Em) and altered surface expression of K+ channels. Epithelial cell migration in response to the wounding of confluent IEC-6 and IEC-Cdx2 monolayers was reduced by indomethacin (100μM), phenylbutazone (100μM) and NS-398 (100μM) but not by SC-560 (1μM). NSAID-inhibition of intestinal cell migration was not associated with depletion of intracellular polyamines. Treatment of IEC-6 and IEC-Cdx2 cells with indomethacin, phenylbutazone and NS-398 induced significant depolarization of Em, whereas treatment with SC-560 had no effect on Em. The Em of IEC-Cdx2 cells was: −38.5±1.8mV under control conditions; −35.9±1.6mV after treatment with SC-560; −18.8±1.2mV after treatment with indomethacin; and −23.7±1.4mV after treatment with NS-398. Whereas SC-560 had no significant effects on the total cellular expression of Kv1.4 channel protein, indomethacin and NS-398 decreased not only the total cellular expression of Kv1.4, but also the cell surface expression of both Kv1.4 and Kv1.6 channel subunits in IEC-Cdx2. Both Kv1.4 and Kv1.6 channel proteins were immunoprecipitated by Kv1.4 antibody from IEC-Cdx2 lysates, indicating that these subunits co-assemble to form heteromeric Kv channels. These results suggest that NSAID inhibition of epithelial cell migration is independent of polyamine-depletion, and is associated with depolarization of Em and decreased surface expression of heteromeric Kv1 channels.ID: S0006295207001931; M3: Article; Accession Number: S0006295207001931; Author: L.C. Freeman (b); Author: D.F. Narvaez (a); Author: A. McCoy (a); Author: F.B. von Stein (c); Author: S. Young (b); Author: K. Silver (a); Author: S. Ganta (b); Author: D. Koch (b); Author: R. Hunter (b); Author: R.F. Gilmour (c); Author: J.D. Lillich (a, ⁎); Affiliation: Department of Clinical Sciences, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, United States; Keyword: Non-steroidal anti-inflammatory drugs; Keyword: Intestinal epithelial cells; Keyword: Membrane potential; Keyword: Potassium channels; Number of Pages: 12; Language: English;Source type: Electronic(1)http://search.ebscohost.com/login.aspx?direct=true&db=edselp&AN=S0006295207001931&site=eds-live&scope=sit

    Les Observations sur l'éloquence de l'abbé de Saint-Pierre

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    Abbé de Saint-Pierre : Observations sur l'éloquence. Presented by Lawrence Kerslake. Many of the abbé de Saint-Pierre's writings remain little-known or even unpublished. The Observations sur l'éloquence constitute his chief discussion of literature. A preliminary draft appeared in the Mercure in 1726, but the work subsequently underwent two major revisions, both states represented in Ms. R.248 of the Bibliothèque publique et universitaire in Neuchâtel. A further copy (BNF. N.a.fr. 11232), with a few additional changes, is published here. The ideas in the text show the author to be a 'Modern' in his position on beauty and literary effect, and reflect his life-long concern for the improvement of his fellow-citizens.Kerslake L.C. Les Observations sur l'éloquence de l'abbé de Saint-Pierre. In: Dix-huitième Siècle, n°31, 1999. Mouvement des sciences et esthétique(s) sous la direction de Christine Rolland, François Azouvi et Michel Baridon. pp. 305-328

    A 0.53pJK<sup>2</sup> 7000μm<sup>2</sup> resistor-based temperature sensor with an inaccuracy of ±0.35°C (3σ) in 65nm CMOS

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    In microprocessors and DRAMs, on-chip temperature sensors are essential components, ensuring reliability by monitoring thermal gradients and hot spots. Such sensors must be as small as possible, since multiple sensors are required for dense thermal monitoring. However, conventional BJT-based temperature sensors are not compatible with the sub-1V supply of advanced processes. Subthreshold MOSFETs can operate from lower supplies, but at high temperatures their performance is limited by leakage [1,2]. Thermal diffusivity (TD) sensors achieve sub-1V operation and small area with moderate accuracy, but require milliwatts of power [3]. Recently, resistor-based sensors based on RC WienBridge (WB) filters have realized high resolution and energy efficiency [4,5]. Fundamentally, they are robust to process and supply-voltage scaling. However, their readout circuitry has been based on continuous-time (CT) ΔΣ ADCs or frequency-locked loops (FLLs), which require precision analog circuits and occupy considerable area (&gt;0.7mm 2 ).Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Microelectronic

    A ±4A high-side current sensor with 25V input CM range and 0.9% gain error from -40°C to 85°C using an analog temperature compensation technique

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    This paper presents a fully integrated ±4A current sensor that supports a 25V input common-mode voltage range (CMVR) while operating from a single 1.5V supply. It consists of an on-chip metal shunt, a beyond-the-rails ADC [1] and a temperature-dependent voltage reference. The beyond-the-rails ADC facilitates high-side current sensing without the need for external resistive dividers or level shifters, thus reducing power consumption and system complexity. To compensate for the shunt's temperature dependence, the ADC employs a proportional-to-absolute-temperature (PTAT) reference voltage. Compared to digital temperature compensation schemes [2,3], this analog scheme eliminates the need for a temperature sensor, a band-gap voltage reference and calibration logic. As a result, the current sensor draws only 10.9μA and is 10x more energy efficient than [2]. Over a ±4A range, and after a one-point trim, the sensor exhibits a 0.9% (max) gain error from -40°C to 85°C and a 0.05% gain error at room temperature. The former is comparable with that of other fully-integrated current sensors [2-4], while the latter represents the state-of-the-art.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic

    A phase-domain readout circuit for a CMOS-compatible thermal-conductivity-based carbon dioxide sensor

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    The measurement of carbon-dioxide (CO2) concentration is very important in home and building automation, e.g. to control ventilation in energy-efficient buildings. This application requires compact, low-cost sensors that can measure CO2 concentration with a resolution of &lt;200 ppm over a 2500ppm range. Conventional optical (NDIR-based) CO2 sensors require components that are CMOS-incompatible, difficult to miniaturize and power-hungry [1]. Due to their CMOS compatibility, thermal-conductivity-based sensors are an attractive alternative [2,3]. They exploit the fact that the thermal conductivity (TC) of CO2 is lower than that of the other constituents of air, so that CO2 concentration can be indirectly measured via the heat loss of a hot wire to ambient. However, this approach requires the detection of very small changes in TC (0.25 ppm per ppm CO2 [3]).Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic
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