1,721,090 research outputs found
Study and management of zoonoses transmitted by wild animals
No full textIn the present work the criteria to approach the study, the prophylaxis and the control of wildlife-related zoonoses are discussed, along with the role of veterinarians as responsible for wildlife and public health management. More in detail, the ecological method in approaching the study of wildlife infections is discussed, along with the relationships existing among hosts, parasites and the environment. Finally, the role of man as a host of zoonotic agents is discussed, and the basic principles of prophylaxis and control of infections caused by such agents are also considered.[...
Amyloid, amyloid-inducers, cytokines and heavy metals in scrapie and other human and animal subacute spongiform encephalopathies: Some hypotheses
No full textA number of hypotheses regarding the pathogenesis of scrapie and other human and animal spontaneous and experimental subacute spongiform encephalopathies (SSE) are presented here. In particular, it is speculated that a PrPsc 27-30-induced suppression of host's defense system is responsible, through the existence of the different and synergistically operating mechanisms, for the absence of any documented inflammatory or immunologic response during SSE. This could be therapeutically counterparted by the utilization of cytokines (TNF, IL-1, etc) or cytokine-inducers, provided that synthesis and secretion of the above inflammation mediators on behalf of reticulo-endothelial cells were strongly depressed by PrP 27-30, as suggested. Finally, some hypotheses are also made in relation to the blood-brain-barrier's integrity in susceptible hosts. Similarly to Alzheimer's disease (AD) in man, this could play a role also in SSE pathogenesis, facilitating cerebral localization of metals such as aluminum, lead, or silica, which have already been shown to enhance amyloid fibrils' polymerization and deposition within human brain tissue.[...
Nucleolar size and mitotic index in Basal cell carcinomas (BCC) and Squamous cell carcinomas (SCC) of canine skin.
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Nucleolar size and mitotic index in Basal cell carcinomas (BCC) and Squamous cell carcinomas (SCC) of canine skin.
No full textBovine spongiform encephalopathy: An overview (Review article)
No full textBovine spongiform encephalopathy (BSE), a novel disease of cattle first described in 1986, has now reached epidemic proportion in Great Britain with about 500 cases a week. The clinical, epidemiological, and pathological characteristics of BSE are described. Moreover, the etiopathogenetic mechanisms of spongiform encephalopathies are reviewed. Legislative measures to prevent the spread of BSE in Italy and in other EEC countries and to minimize the theoretical risk to man are reported.[...
Squamous cell carcinoma of the skin in a Père David's deer (Elaphurus davidianus)
No full textA solitary mass overlying the right carpal joint region's skin in an 18-year-old female Père David's deer (Elaphurus davidianus) was surgically excised and histologically diagnosed as a squamous cell carcinoma (SCC). The tumor was locally infiltrative, showing rather few "horn pearls" and many mitotic figures. This is the first report of a cutaneous SCC in the Père David's deer.[...
L’infezione da Morbillivirus nei delfini ed in altre specie di mammiferi acquatici (Review)
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