804 research outputs found
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Aditya Kulkarni: Modèles de mobilité humaine liés aux emplacements sujets au COVID-19
No full textCette présentation a été faite par Aditya Kulkarni. Le titre de la présentation est: “Modèles de mobilité humaine liés aux emplacements sujets au COVID-19.”
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Chaque mois, l'équipe COVID Information Commons (avec le Northeast Big Data Innovation Hub) rassemble un groupe de chercheurs étudiant de nombreux aspects de la pandémie actuelle, pour partager leurs recherches et répondre aux questions de notre communauté. Ces événements mettent en valeur les efforts continus des scientifiques dans la lutte contre le COVID-19, notamment les opportunités de collaboration
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Aditya Kulkarni: Human Mobility Patterns Linked to COVID-19 Prone Locations
No full textThis presentation was made by Aditya Kulkarni, University of Minnesota. The presentation’s title is: “Human Mobility Patterns Linked to COVID-19 Prone Locations.” COVID Information Commons Undergraduate Student Paper Challenge 3rd Place Winner.
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Every month, the COVID Information Commons Team (along with the Northeast Big Data Innovation Hub) brings together a group of researchers studying wide-ranging aspects of the current pandemic, to share their research and answer questions from our community. The events showcase scientists' ongoing efforts in the fight against COVID-19, including opportunities for collaboration
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Aditya Kulkarni: Patrones de movilidad humana vinculados a ubicaciones propensas a COVID-19
No full textDescripción de esta presentación:
Esta presentación fue hecha por Aditya Kulkarni, Universidad de Minnesota. El título de la presentación es: "Patrones de Movilidad Humana Vinculados a Ubicaciones Propensas COVID-19." Centro de Información de COVID. Estudiante de Pregrado del reto estudiantil. Ganador del 3er lugar.
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Descripción de los seminarios web del CIC:
Cada mes, el equipo del Centro de Información de COVID (junto con el Northeast Big Data Innovation Hub) reúne a un grupo de investigadores que estudian diversos aspectos de la pandemia actual, para compartir sus investigaciones y responder preguntas de nuestra comunidad. Los eventos muestran los esfuerzos continuos de los científicos en la lucha contra el COVID-19, incluyendo oportunidades de colaboración
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Aditya Kulkarni: कोविड-19 प्रवण स्थानों से जुड़े मानव गतिशीलता पैटर्न
No full text"यह प्रस्तुति आदित्य कुलकर्णी (मिनेसोटा विश्वविद्यालय) द्वारा की गई थी। प्रस्तुति का शीर्षक है: "कोविड-19 प्रवण स्थानों से जुड़े मानव गतिशीलता पैटर्न।"
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हर महीने, कोविड सूचना कॉमन्स टीम (नॉर्थईस्ट बिग डेटा इनोवेशन हब के साथ) वर्तमान महामारी के व्यापक पहलुओं का अध्ययन करने वाले शोधकर्ताओं के एक समूह को एक साथ लाती है, ताकि वे अपने शोध को साझा कर सकें और हमारे समुदाय के सवालों के जवाब दे सकें। ये कार्यक्रम कोविड-19 के खिलाफ़ लड़ाई में वैज्ञानिकों के चल रहे प्रयासों को प्रदर्शित करते हैं, जिसमें सहयोग के अवसर भी शामिल हैं।
Four ways to improve and strengthen your supply chain
No full textDileep Kulkarni, Senior Principal Consultant - Expense Reduction Analysts, Inc.Title from PDF caption (viewed on June 14, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Selectivity for dimers in pentene oligomerization over acid zeolites
No full textThe reactions of 1-pentene over acid zeolites were investigated in the liquid phase at 473 K. The primary reactions were isomerization, dimerization, and subsequent cracking of dimers. Zeolites consisting of only 10-membered (MFI) or 12-membered rings (FAU, BEA) behaved similarly, with dimerization and subsequent cracking products observed. Zeolites possessing 8-membered ring pores (MOR, FER) showed very different selectivity from each other and from other zeolites. MOR showed almost complete conversion of C10 olefins, such that hexene and butene from cracking were the dominant products. FER showed high activity and selectivity for dimerization, with very small amounts of cracking products observed.Peer reviewe
Understanding COVID-19 Effects on Mobility: A Community-Engaged Approach
No full textGiven aggregated mobile device data, the goal is to understand the impact of COVID-19 policy interventions on mobility. This problem is vital due to important societal use cases, such as safely reopening the economy. Challenges include understanding and interpreting questions of interest to policymakers, cross-jurisdictional variability in choice and time of interventions, the large data volume, and unknown sampling bias. The related work has explored the COVID-19 impact on travel distance, time spent at home, and the number of visitors at different points of interest. However, many policymakers are interested in long-duration visits to high-risk business categories and understanding the spatial selection bias to interpret summary reports. We provide an Entity Relationship diagram, system architecture, and implementation to support queries on long-duration visits in addition to fine resolution device count maps to understand spatial bias. We closely collaborated with policymakers to derive the system requirements and evaluate the system components, the summary reports, and visualizations.Sharma, Arun; Farhadloo, Majid; Li, Yan; Kulkarni, Aditya; Gupta, Jayant; Shekhar, Shashi. (2022). Understanding COVID-19 Effects on Mobility: A Community-Engaged Approach. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/226039
Linear cyclodextrin polymer prodrugs as novel yherapeutics for Niemann-Pick type C1 disorder
No full textNiemann-Pick Type C1 disorder (NPC) is a rare lysosomal storage disease characterized by the accumulation of cholesterol in lysosomes. NPC has no FDA approved treatments yet, however 2-hydroxypropyl-β-cyclodextrin (HPβCD) has shown efficacy for treating the disease in both mouse and feline NPC models and is currently being investigated in late stage clinical trials. Despite promising results, therapeutic use of HPβCD is limited by the need for high doses, ototoxicity and intrathecal administration. These limitations can be attributed to its poor pharmacokinetic profile. In the attempt to overcome these limitations, we have designed a β-cyclodextrin (βCD) based polymer prodrugs (ORX-301) for an enhanced pharmacokinetic and biodistribution profile, which in turn can potentially provide an improved efficacy at lower doses. We demonstrated that subcutaneously injected ORX-301 extended the mean lifespan of NPC mice at a dosage 5-fold lower (800 mg/kg, body weight) the HPβCD dose proven efficacious (4000 mg/kg). We also show that ORX-301 penetrates the blood brain barrier and counteracts neurological impairment. These properties represent a substantial improvement and appear to overcome major limitations of presently available βCD-based therapy, demonstrating that this novel prodrug is a valuable alternative/complement for existing therapies
Electron cyclotron resonance frequency system on tokamak Aditya
No full textA 28 GHz ECRH system has been successfully commissioned on the tokamak Aditya to carry out breakdown, start up and heating experiments. The microwave source gyrotron VGA8000A19 capable of delivering 200 kW CW is commissioned and tested with a water dummy load for pulsed operation. The output mode of the gyrotron (TE02) is externally converted to the HE11 mode with the help of a mode converter and Matching Optics Unit of the transmission line. The transmission line consists of a mode converter, MOU, DC breaks, mitre bend, polarizer unit and different sizes of corrugated waveguides. The total transmission loss of the transmission line including 10 m long waveguides is measured to be less than 1.1 dB. The burn patterns at different locations of the transmission line confirm the mode purity to be better than 93% in the TE02 mode. The transmission line terminates at a launcher box through a barrier window. The ECRH launcher consists of two mirrors to focus the microwave beam at the plasma center. The first mirror is convex while the second mirror is a concave focusing mirror. The mirrors are designed based on quasi optical analysis of the launcher system. The focal length of second mirror is 392.9 mm, which focuses the microwave beam to 35 mm (beam waist radius) at the plasma center. Beam steering in the plasma volume is restricted to ±2°. The gyrotron is tested up to ∼80 kW output power. A hard-wired interlock for various fault conditions, operates a rail-gap crowbar in less than 10 μS to protect the gyrotron. The gyrotron output is coupled to the tokamak Aditya (O-mode, perpendicular launch from low field side) and successful breakdown of the neutral gas is observed at different tokamak parameters. The paper describes the technical aspects of commissioning of the ECRH system and breakdown results on Aditya.© IEE
Spariolenus omidvarbrothers Moradmand & Wesal & Kulkarni 2023, sp. n.
No full text<i>Spariolenus omidvarbrothers</i> sp. n. <p>Figs 1A–C, 2A–D, 9A, 11A–C</p> <p> <b>Type material.</b> <b>Holotype:</b> male, <b> IRAN: <i>Sistan & Baluchestan Province:</i></b> Barashk, Bidan Oasis valley, 26.61 N, 60.35 E, 1336 m, 5 June 2017, M. Moradmand & H. Salehi leg. (SMF). <b>Paratypes:</b> 2 females with same data as for holotype (SMF).</p> <p> <b>Etymology.</b> The species is named in honour of the Omidvar brothers, two Iranian adventurers and explorers who travelled around the world in the 1950s and produced a diary and one of the first travel documentaries from extremely remote areas. Their biography inspired the life of many generations including the first author; noun in apposition.</p> <p> <b>Diagnosis.</b> Males of the new species share the bifurcated ET with <i>S. zagros</i> Moradmand & Jäger, 2011; <i>S. fathpouri</i> Moradmand, 2017; <i>S. mansourii</i>, and <i>S. bakasura</i> <b>sp. n.</b>). They can be distinguished from the latter three species by subequal RET and PET (vs. RET obviously longer than PET). They differ from <i>S. zagros</i> by PET 1/3 of RET in width (vs. similar width of PET and RET in <i>S. zagros</i>) (Fig. 1C). The female epigyne shows a unique MS (widened medially and extended longitudinally, Fig. 2A) (vs. MS narrow and barely visible in the rest of congeners).</p> <p> <b>Male</b> (holotype): <i>Measurements.</i> TL 14.1, PL 6.6, PW 5.7, AW 2.5, OL 7.5, OW 4.5. <i>Eyes</i> (Fig 11A). AME 0.33, ALE 0.75, PME 0.48, PLE 0.83, eye interdistances: AME-AME 0.18, AME-ALE 0.03, PME-PME 0.17, PME-PLE 0.62, AME-PME 0.21, ALE-PLE 0.57, clypeus-AME 0.71, clypeus-ALE 0.21. <i>Spination.</i> Palp 131, 101, 2121; Legs: Femur I–III 323(2), IV 321; Patella I–IV 101; Tibia I 131 10, II 232 10, III 1318, IV 2226; Metatarsus I–III 1014, IV 3036. <i>Measurements of palp and legs.</i> Palp 9.8 [3.2, 1.3, 2.2, 3.1], I 40.6 [10.8, 3.8, 11.5, 11.7, 2.8], II 46.0 [12.2, 4.1, 13.7, 13.2, 2.8], III 35.2 [10.1, 3.7, 10.2, 9.1, 2.1], IV 36.0 [10.2, 3.1, 10.2, 10.1, 2.4]. Leg formula: II I IV III. Chelicerae with 3 promarginal and 5 retromarginal teeth, and 10 intermarginal denticles.</p> <p> <i>Palp.</i> As in diagnosis, with cymbium slightly longer than tibia, BRB present, vRTA shorter than dRTA, dRTA pointed and vRTA rounded in retrolateral view, PET slightly shorter than RET, and both are long and slim, and not covering each other in ventral view. Conductor hyaline and extending beyond or roughly the same length as ET (Figs 1A–C).</p> <p> <i>Colouration.</i> Light brown to beige in body with dim to dark grey bands on carapace and legs. Dorsal opisthosoma with chevron shaped markings (Fig. 11A).</p> <p> <b>Female</b> (paratype): <i>Measurements.</i> TL 13.5, PL 7.2, PW 6.3, AW 3.6, OL 6.3, OW 4.5. <i>Eyes.</i> AME 0.31, ALE 0.80, PME 0.50, PLE 0.97, eye inter distances:AME-AME 0.18, AME-ALE 0.07, PME-PME 0.27, PME-PLE 0.63, AME-PME 0.32, ALE-PLE 0.71, clypeus-AME 0.87, clypeus-ALE 0.28. <i>Measurements of palp and legs.</i> Palp 10.4 [3.1, 1.7, 2.3, 3.3], I 32.8 [9.1, 3.8, 9.6, 8.1, 2.2], II [missing], III 29.6 [8.7, 3.5, 8.2, 7.1, 2.1], IV 31.1 [9.1, 3.6, 8.5, 7.8, 2.1]. <i>Spination.</i> Palp 131, 101, 2221, 1014; Legs (leg II missing): Femur I, III 323, IV 321; Patella I, III–IV 001; Tibia I 111(10), III 1118, IV 2126; Metatarsus I, III 1014, IV 3036. Chelicerae with 3 promarginal and 5 retromarginal teeth, cheliceral furrow with around 20 intermarginal denticles.</p> <p> <i>Female copulatory organ.</i> As in diagnosis, with EF wider than long, AB absent, CO small, MEP diagonaly extended (Fig. 2A); TC extending laterad beyond FC and SC (Figs 2B–C).</p> <p> <i>Colouration.</i> Same as for male but with lighter colour bands on legs (Fig. 11B).</p> <p> <b>Distribution and habitat preferences.</b> Known only from the type locality (Fig. 13). Specimens were collected at night on boulders and rocks. The type locality was an oasis in a small canyon dominated by palm trees (Fig. 11C). An unknown species of the genus <i>Eusparassus</i> Simon, 1903 was sympatrically sampled on plants and vegetation.</p>Published as part of <i>Moradmand, Majid, Wesal, Mohammad Wasil & Kulkarni, Siddharth, 2023, Taxonomic revision of the troglophile Spariolenus spiders (Araneae: Sparassidae) in South and West Asia, pp. 77-95 in Zootaxa 5380 (1)</i> on pages 78-81, DOI: 10.11646/zootaxa.5380.1.6, <a href="http://zenodo.org/record/10212761">http://zenodo.org/record/10212761</a>
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