3 research outputs found
Phytochemical and Metabolomic Profiles of Ethanolic Extract of Curculigo pilosa Rhizomes for Animal Health
No full textCurculigo pilosa is traditionally used in herbal medicine. This study aims to provide information on the secondary metabolites present in C. pilosa rhizomes powder, considering the growing interest in ethnomedicines in recent times. The rhizomes of C. pilosa were purchased from markets around Ogere, Ogun State, Nigeria. They were authenticated by a botanist, after which the rhizomes were washed and extracted using ethanol. The phytochemical composition and metabolomic profiles of the ethanolic extracts of C. pilosa were determined using gas chromatographic-mass spectrometric (GC-MS) methods. The results showed that the ethanolic extracts of C. pilosa had higher concentrations of phenols (9.27 ± 0.55 mg GAE/g), alkaloids (6.22 ± 1.95 g/100g), flavonoids (0.66 ± 0.05 g/100g), and saponins (0.51 ± 0.02 g/100g), but lower concentrations of glycosides (0.06 ± 0.01 g/100g), steroids (0.20 ± 0.02 g/100g), and tannins (0.09 ± 0.01 g/100g). The twenty-one bioactive compounds found in the extract include tetraethyl silicate (C₈H₂₀O₄Si), benzene, 1,2-dimethoxy- (C₈H₁₀O₂), 5-dodecene, (Z)- (C₁₂H₂₄), 7-tetradecene, (E)- (C₁₄H₂₈), spirohexane-1-carboxylic acid, ethyl ester (C₉H₁₄O₂), 1-dodecanol, 2-octyl- (C₂₀H₄₂O), formaldehyde, methyl (2-propynyl) hydrazone (C₅H₈N₂), D-allose (C₆H₁₂O₆), cyclohexane, 1R-acetamido-2cis,4trans-bis(acetoxy)-3trans-azido- (C₁₂H₂₂N₄O₅), 5-octadecene, (E)- (C₁₈H₃₆), acetamide, 2-(4-hydroxy-3-methoxyphenyl)- (C₁₁H₁₅NO₃), cyclopentanol, 1-(1-methylene-2-propenyl)- (C₉H₁₄O), 1,9-tetradecadiene (C₁₄H₂₆), 9-eicosine, (E) (C₂₀H₄₀), hexadecyl propyl ether (C₁₉H₄₀O), 9-octadecene, (E)- (C₁₈H₃₆), linoleic acid ethyl ester (C₂₀H₃₄O), 2-methyl-Z,Z-3,13-octadecadienol (C₁₉H₃₆O), 3-octadecene, (E)- (C₁₈H₃₆), 3-heptadecenal (C₁₇H₃₂O), tricyclo[5.4.3.0(1,8)] tetradecan-6-one, and 4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl (C₂₀H₃₂O₂). Some of the phytocompounds identified in this study are biologically important and exhibit antimicrobial, antioxidant, and anti-inflammatory properties, which may hold therapeutic potential for both animal and human health
Proteomic profiling: A tool to unlock the potential of Nigerian indigenous goats
No full textNigeria possesses a rich diversity of indigenous goats (predominantly the West African Dwarf, Sokoto Red and Sahel goats), that are superbly adapted to local environment but often underperform compared to improved breeds. Proteomic profiling emerges as a powerful avenue to bridge this gap. This approach examines the protein content of an organism, providing insights into its genetic potential. In the case of Nigerian indigenous goats, this method can reveal valuable information about their unique traits, disease resistance, and potential for improvement through selective breeding. This review underscores how integrating proteomic profiling into breeding programs can unlock genetic potential of Nigerian indigenous goats. It is however concluded that with the use of technologies involved in proteomic profiling, strategies can be formulated for Nigerian indigenous goat breeds to improve their productivity, health, and product quality. With strategic application of these technologies, supported by ongoing research and investment, proteomics can empower Nigerian goat farmers to tap into the vast potential of their indigenous breeds thus offering a powerful approach to unlocking the genetic diversity and adaptive potential of Nigerian indigenous goats. Ultimately, proteomic profiling can boost productivity, animal health and product quality, empowering Nigerian goat producers to leverage the full spectrum of their breeds’ adaptive diversity
Nutrigenomics: A tool to unlock genetic potential of Nigerian indigenous goat breeds
No full textNigerian indigenous goats represent a valuable genetic resource for meat and milk production. However, their productivity often falls below their genetic potential due to suboptimal nutrition. Nutrigenomics offers a revolutionary approach to bridge this gap by exploring the interaction between nutrients and goat genes. It explores how nutrigenomic tools can be used to identify gene variants associated with feed efficiency, meat quality, and milk production. There are various technologies designed to ensure genetic potentials are realized. Nutrigenomics is aimed at exploiting the non-coding section of an individual's genome, which is being disregarded in traditional animal nutrient requirement assessment. Nutrigenomic technology has the potential to unlock the genetic potentials of animals and essentially help to confront nutritional challenges, particularly in Nigerian indigenous goats, of which there is a dearth of information on nutritional needs and requirements. This review delves into the potential of nutrigenomics to unlock the genetic potential of Nigerian indigenous goats. Additionally, the review discusses the challenges and future directions of nutrigenomic research in Nigerian goats. By implementing nutrigenomic strategies, Nigerian goat production can be revolutionized, leading to increased productivity, improved product quality, and enhanced farmer livelihoods. It is hoped that this review will provide vital information to aid research in utilizing the nutrigenomics potential of unlocking the genetic potentials and reproductive performance of Nigerian indigenous goats through nutrition. [Open Vet. J. 2025; 15(6.000): 2298-2311
