2,541 research outputs found
Address by President M.O. Morgan opening of Engineering/Geology Building, October 20, 1977
No full textAddress by President M.O. Morgan,Opening of Engineering-Geology Building, October 20, 1977Title from captio
Data for "Fast Approximate STEM Image Simulations from a Machine Learning Model"
No full textThis data set contains all the data for the following paper:
Fast Approximate STEM Image Simulations from a Machine
Learning Model, Aidan H. Combs, Jason J. Maldonis, Jie Feng, Zhongnan Xu, Paul
M. Voyles, Dane Morgan, published in the journal Advanced Structural and Chemical Imaging (2019).
DOI : 10.1186/s40679-019-0064-2
ASCI-D-18-00004.4Contact author: Dane Morgan </p
Author Correction: Environmental variability supports chimpanzee behavioural diversity
Full text linkThe original version of the Supplementary Information associated with this Article included an incorrect Supplementary Data 1 file, in which three columns (L, M and P) had slightly different variable names from those written in the code. The HTML has been updated to include a corrected version of Supplementary Data 1; the correct version of Supplementary Data 1 can be found as Supplementary Information associated with this Correction.Additional co-authors: Mattia Bessone, Gregory Brazzola, Valentine Ebua Buh, Rebecca Chancellor, Heather Cohen, Charlotte Coupland, Bryan Curran, Emmanuel Danquah, Tobias Deschner, Dervla Dowd, Manasseh Eno-Nku, J. Michael Fay, Annemarie Goedmakers, Anne-Céline Granjon, Josephine Head, Daniela Hedwig, Veerle Hermans, Sorrel Jones, Jessica Junker, Parag Kadam, Mohamed Kambi, Ivonne Kienast, Deo Kujirakwinja, Kevin E. Langergraber, Juan Lapuente, Bradley Larson, Kevin C. Lee, Vera Leinert, Manuel Llana, Sergio Marrocoli, Amelia C. Meier, David Morgan, Emily Neil, Sonia Nicholl, Emmanuelle Normand, Lucy Jayne Ormsby, Liliana Pacheco, Alex Piel, Jodie Preece, Martha M. Robbins, Aaron Rundus, Crickette Sanz, Volker Sommer, Fiona Stewart, Nikki Tagg, Claudio Tennie, Virginie Vergnes, Adam Welsh, Erin G. Wessling, Jacob Willie, Roman M. Wittig, Yisa Ginath Yuh, Klaus Zuberbühler & Hjalmar S. Küh
Persistent hyperammonemia in two related Morgan weanlings
No full textPersistent hyperammonemia was diagnosed in 2 Morgan fillies with clinical signs that developed early in the postweaning period. Diagnostic evaluation, including routine serum chemistries, CBC, liver biopsy, hepatic ultrasonography, liver function test, and necropsy findings did not support a toxic, developmental, or infectious cause. Abnormal serum amino acid and urine orotic acid concentrations suggest that the foals may have had an inherited disorders described in humans as hyperornithinemia, hyperammonemia, and homocitrullinuria (HHH) syndrome. The disorder is thought to be caused by a defective mitochondrial transporter protein, such that ornithine, required for complete urea synthesis, is deficient, thus causing increases in blood ammonia and ornithine concentrations.LR: 20061115; PUBM: Print; JID: 8708660; 0 (Amino Acids); 7006-33-9 (Ornithine); 7664-41-7 (Ammonia); ppublishSource type: Electronic(1
Light Therapy for Managing Sleep, Behaviour, and Mood Disturbances in Dementia (Review)
Full text linkBackground Rest-activity and sleep-wake cycles are controlled by the endogenous circadian rhythmgenerated by the suprachiasmatic nuclei (SCN) of the hypothalamus. Degenerative changes in the SCN appear to be a biological basis for circadian disturbances in people with dementia, and might be reversed by stimulation of the SCN by light. Objectives The review assesses the evidence of efficacy of bright light therapy (BLT) inmanaging sleep, behaviour,mood, and cognitive disturbances associated with dementia. Search strategy The trials were identified from a search of the Specialized Register of the Cochrane Dementia and Cognitive Improvement Group on 5 December 2005 using the terms “bright light*”, “light box*”, “light visor*”, “dawn-dusk*”, phototherapy (MESH), phototherapy, “photo therapy”, “light therapy” “light treatment”, light*. Selection criteria All relevant, randomized controlled trials in which BLT, at any intensity and duration, was compared with a control group for the effect on managing sleep, behavioural, mood, or cognitive disturbances (as well as changes in institutionalization rates or cost of care) on people with dementia of any degree of severity. Data collection and analysis Three reviewers independently assessed the retrieved articles for relevance and methodological quality, and extracted data from the selected studies. Statistically significant differences in changes in outcomes from baseline to end of treatment and from baseline to follow-up, between the light therapy and control groups, were examined. Each study was summarized using a measure of effect (e.g. mean difference). Owing to lack of homogeneity between studies, their results were not combined. Main results Five studies met the inclusion criteria. However, only three were included in the analyses because of inappropriate reported study analyses or inability to retrieve the required data from the investigators. This review revealed no adequate evidence of the effectiveness of BLT in managing sleep, behaviour, cognitive, or mood disturbances associated with dementia. Authors’ conclusions There is insufficient evidence to assess the value of BLT for people with dementia. The available studies are of poor quality and further research is required. P L A I N L A N G U A G E S U M M A R Y There is insufficient evidence to determine whether bright light therapy is effective in the management of sleep, behaviour, mood, or cognitive disturbances in dementia. Rest-activity and sleep-wake cycles are controlled by the endogenous circadian rhythm generated by the suprachiasmatic nuclei (SCN) of the hypothalamus. Degenerative changes in the SCN appear to be a biological basis for circadian disturbances in people with dementia, and might be reversed by stimulation of the SCN by light. The light sources in the included studies were: a light box placed approximately one metre away from the subjects at a height within their visual fields; a light visor worn on their heads; or a more acceptable ’naturalistic’ light therapy, known as dawn-dusk simulation that mimics outdoor twilight transitions. Five studies met the inclusion criteria. However, only three were included in this analysis because of inappropriately reported analyses or inability to retrieve the required data from the original investigators. The three studies included in the analysis were of poor quality and revealed no adequate evidence of the effectiveness of bright light therapy (BLT) in managing sleep, behaviour, or mood disturbances associated with dementia
Judicial Notice -- Excerpts Relating to the Morgan-Wignore Controversy
Full text linkAuthor\u27s Note: These two excerpts are from the author\u27s preliminary draft of his proposed revision of the judicial notice chapter of Wigmore on Evidence. The excerpts are submitted for publication in this Edmund M. Morgan issue of the Vanderbilt Law Review for two reasons: First, because of the important role played by Professor Morgan in the recent development and articulation of the law of judicial notice and, second, because Professor Morgan and Dean Wigmore stand at opposite poles in the argument over judicial notice. At least they do with respect to one significant particular. They do not differ with respect to the application of the doctrine to law. Nor do they reveal a difference with respect to so-called jury notice. Their difference relates to judicial notice of facts. Here Wigmore, following Thayer, insists that judicial notice is solely to save time where dispute is unlikely and that a matter judicially noticed is therefore only prima facie, or rebuttable, if the opponent elects to dispute it. It is express in Thayer and implicit in Wigmore that (perhaps because the matter is rebuttable) judicial notice may be applied not only to indisputable matters but also to matters of lesser certainty. Morgan on the other hand defines judicial notice more narrowly, and his consequences follow from his definition. He limits judicial notice of fact to matters patently indisputable. And his position is that matters judicially noticed are not rebuttable
Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes
No full textGenetic instability, including chromosomal imbalance, is important in the pathogenesis of lymphoproliferative disorders such as non–Hodgkin lymphoma (NHL). DNA synthesis and methylation, which are closely linked to folate metabolism and transport, may be affected by polymorphisms in genes involved in these pathways. Folate metabolism polymorphisms have been linked to acute lymphoblastic leukemia and colorectal cancer. To evaluate whether genetic variation in folate metabolism and transport may have a role in determining the risk of developing NHL, we analyzed several polymorphisms using DNA obtained as part of a large U.K. population-based case-control study of lymphoma. Polymorphisms studied include methylenetetrahydrofolate reductase (MTHFR) 677 C>T and 1298 A>C, methionine synthase (MTR) 2756 A>G, serine hydroxymethyltransferase (SHMT1) 1420 C>T, thymidylate synthase (TYMS) 1494del6 and 28–bp repeat, and reduced folate carrier (RFC) 80 G>A. Increased risks for NHL [odds ratio (OR), 1.48; 95% confidence intervals (CI), 1.12-1.97], and marginal zone lymphoma (OR, 3.38; 95% CI, 1.30-8.82) were associated with the TYMS 2R/3R variant. Marginal increased risks were also observed for diffuse large B cell lymphoma with the TYMS homozygous 6 bp deletion (OR, 1.61; 95% CI, 0.99-2.60) and for follicular lymphoma with RFC 80AA (OR, 1.44; 95% CI, 0.94-2.22) and TYMS 28–bp repeat 2R/3R (OR, 1.45; 95% CI, 0.96-2.2). We observed no association between NHL and haplotypes for MTHFR or TYMS. These findings are somewhat inconsistent with those of others, but may reflect differences in circulating folate levels between study populations. Thus, further investigations are warranted in larger series with dietary information to determine the roles that genetics and folic acid status play in the etiology of lymphoma. (Cancer Epidemiol Biomarkers Prev 2005;14(12):2999–3003
Intern experience at MEL, Incorporated, Inc., Baton Rouge, Louisiana: an intern report
Full text linkIncludes author's vita"Submitted to the College of Engineering of Texas A&M University in partial
fulfillment of the requirement for the degree of Doctor of Engineering."Includes bibliographical references (leaf 39)As a requirement of the Doctor of Engineering program, the author spent
a one year internship at MEL, Inc., an engineering consulting firm located in Baton Roughe,
Louisiana. During this period, he was responsible for the following assignments: 1. specifying
the appropriate computer to implement an existing financial management system, 2. developing a
"Project Management Quality Control Manual" which contains guidelines and checklists for the
management and administration of a project from conception through completion, 3. designing
the mechanical systems on a lift span bridge to be constructed over Bayou Grain Caillou in
Terrebonne Parish, Louisiana, 4. serving as project manager on three projects, 5. developing
computer programs for billing clients and keeping drafting time records, and 6. particiipating
in contract negotiations, fee proposal preparation, and Management Committee meetings. These
assignments exposed the author to a broad spectrum of both technical and managerial problems
and practices. The internship experience proved to be a valuable part of his overall
education
Address to Rotary, January 29, 1981
No full textAn Address to Rotary, by M.O. Morgan, January 29, 1981Title from captio
Talk to St. John's Rotary, Thursday, January 22, 1976
No full textTalk to St. John's Rotary by M.O. Morgan, Thursday, January 22, 1976Title from captio
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