2,656,143 research outputs found
Ada Jolly
No full textDate:1861?Ada Bella Gay was born to John and Christine Hughes and christened on 15 May 1861. Her mother remarried a sea captain, Captain W.E. Gay, after the death of her mariner husband and Ada's father. The family arrived in Darwin Port on their hulk, the "Belle of South Esk" in November 1884. Ada married Alfred Ernest Jolly, businessman and joint owner of an importing and general store in Darwin, in 1886 on board her stepfather's boat in harbour. They had three children, two sons (Alfred William born September 1886 and another born 1892 in Adelaide) and a daughter, Kathleen Ada, born soon after the May 1896 election. In 1895 when Ada was 34, she was one of the 82 women who enrolled to vote after the franchise was granted to South Australian and Territory women in 1894. Her occupation was listed as 'married woman'. Ada died in 1939 at her home in North Adelaide at the age of 80.PioneerEnglis
Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID)
No full textAdenosine deaminase deficiency (ADA) is a rare, inherited disorder of purine metabolism characterized by immunodeficiency, failure to thrive and metabolic abnormalities. A lack of the enzyme ADA allows accumulation of toxic metabolites causing defects of both cell mediated and humoral immunity leading to ADA severe combined immune deficiency (SCID), a condition that can be fatal in early infancy if left untreated. Hematopoietic stem cell transplant is curative but is dependent on a good donor match. Other therapeutic options include enzyme replacement therapy (ERT) with pegademase bovine (PEG-ADA) and more recently gene therapy. PEG-ADA has been used in over 150 patients worldwide and has allowed stabilization of patients awaiting more definitive treatment with hematopoietic stem cell transplant. It affords both metabolic detoxification and protective immune function with patients remaining clinically well, but immune reconstitution is often suboptimal and may not be long lived. We discuss the pharmacokinetics, immune reconstitution, effects on systemic disease and side effects of treatment with PEG-ADA. We also review the long-term outcome of patients receiving ERT and discuss the role of PEG-ADA in the management of infants and children with ADA-SCID, alongside other therapeutic options
Ada Gaden
No full textAda married Hazel Frederick Gaden in 1920 they travelled by boat to Darwin, to a live at Kopalgo homestead built by her father in 1880's. Here she raised five of her seven children and followed her husband Hazel on his buffalo shooting trails throughout the Alligator River region. Ada and her children moved to Darwin so the children could be educated and in 1942 during the Second World War they suffered the turmoil of evacuation and returned to the Territory as soon as the military authorities allowed them. She was always helping her Aboriginal and European friends and seldom a day went by that there was not somebody enjoying Ada's hospitality at their home where St John's College now stands. Ada never set time limits for her visitors and she on occasions assisted with marriage ceremonies held at the house where some of the mission girls were married in her garden and she made the wedding frock, provide a wedding cake and assist in organising a church wedding with a reception when the girls asked.
Their house was used as a base for receiving medical treatment by visiting Aborigines from the bush when they were in Darwin and Ada with her knowledge of Aboriginal language picked up during her buffalo shooting days helped provide a communication link between medical practitioners and their patients.Pionee
Correspondence to Ada Peirce McCormick
No full textLetters to Ada Peirce McCormick from Laurent family members. Ada and her husband, Fred, sponsored a struggling family in France after World War I with the help of Elise Whitlock Rose (graduate of Woman's Medical College of Pennsylvania in 1913). McCormick was not a physician and did not have a direct affiliation with WMCP. Her papers are housed at the University of Arizona Library Special Collections and University of Maine Library Special Collections
ADA newsletter
No full textThis archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Correspondence to Ada Peirce McCormick
No full textLetters from Elizabeth Frances C. Clark (graduate of Woman's Medical College of Pennsylvania (WMCP) in 1909) to her friend, Ada Peirce McCormick. The letters reflect the intimate friendship between Clark, McCormick, and Emma Elizabeth Musson (graduate of WMCP in 1883) and daily life as women in medicine. McCormick was not a physician and did not have a direct affiliation with WMCP. Her papers are housed at the University of Arizona Library Special Collections and University of Maine Library Special Collections
Correspondence to Ada Peirce McCormick
No full textLetters to Ada Peirce McCormick. The letters reflect the intimate friendship between Elizabeth Frances C. Clark (graduate of Woman's Medical College of Pennsylvania (WMCP) in 1909), Emma Elizabeth Musson (graduate of WMCP in 1883) and McCormick and daily life as women in medicine. McCormick was not a physician and did not have a direct affiliation with WMCP. Her papers are housed at the University of Arizona Library Special Collections and University of Maine Library Special Collections
Correspondence to Ada Peirce McCormick
No full textLetters to Ada Peirce McCormick. The letters reflect the intimate friendship between Elizabeth Frances C. Clark (graduate of Woman's Medical College of Pennsylvania (WMCP) in 1909), Emma Elizabeth Musson (graduate of WMCP in 1883) and McCormick and daily life as women in medicine. McCormick was not a physician and did not have a direct affiliation with WMCP. Her papers are housed at the University of Arizona Library Special Collections and University of Maine Library Special Collections
Correspondence to Ada Peirce McCormick
No full textLetters to Ada Peirce McCormick. The letters reflect the intimate friendship between Elizabeth Frances C. Clark (graduate of Woman's Medical College of Pennsylvania (WMCP) in 1909), Emma Elizabeth Musson (graduate of WMCP in 1883) and McCormick and daily life as women in medicine. McCormick was not a physician and did not have a direct affiliation with WMCP. Her papers are housed at the University of Arizona Library Special Collections and University of Maine Library Special Collections
Elizabeth F. Clark to Ada Peirce McCormick
No full textLetter from Elizabeth F. Clark to friend, Ada Peirce McCormick. Clark graduated from the Woman's Medical College of Pennsylvania in 1909. Clark graduated Woman's Medical College of Pennsylvania in 1909. McCormick had no direct affiliation with the Woman's Medical College; her papers are housed at the University of Arizona Library Special Collections.test note diacriti
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