1,721,017 research outputs found
Necrotizing cerebellitis due to Neospora caninum infection in an old dog
No full textA severe, necrotizing, non-suppurative inflammation of the cerebellum associated with Neospora caninum infection was identified in a 14-year-old male Labrador Retriever. On presentation, clinical signs included mild depression and head tremor, marked ataxia of both thoracic and pelvic limbs, and abnormal postural reactions. In the central nervous system, inflammatory lesions were mainly restricted to the cerebellar leptomeninges and cerebellar cortex, which appeared necrotic and atrophic. Protozoa] organisms were positively stained with an anti-N. caninum antibody in an immunohistochemical procedure
A case of narcolepsy-cataplexy associated with distemper encephalitis
No full textNarcolepsy associated with localized brain lesions is described in a 10-month-old Argentine Dogo. Neurological examination and MRI study suggested an inflammatory lesion of the left frontal lobe. Post-mortem examination revealed diffuse encephalitis in the forebrain and marked necrotic lesions in the ventral pontine area. Immunohistochemistry for distemper virus antigen showed positive staining of the cytoplasm of many neurones of the pons and cerebral cortex. The pathological pattern was suggestive of post-vaccinal distemper encephalitis and the localization of the lesions was consistent with the neurological syndrome shown by the animal. At any event, the possibility of coincidental findings of distemper encephalitis and idiopathic narcolepsy must be accounted for
Meningeal carcinomatosis in two cats
No full textMultifocal to diffuse meningeal infiltration by neoplastic epithelial cells was observed in two aged cats with neurological signs and a
history of surgical ablation of the auricular pinnae because of the presence of squamous cell carcinoma. In both cats, examination of the
external ear canals revealed neoplastic lesions consistent with squamous cell carcinoma, but no changes of the tympanic bullae were noted. In one cat, post-mortem examination revealed marked thickening of the dura mater and infiltration of the arachnoid layer by cytokeratin-positive,
neoplastic epithelial cells. In the other cat, no macroscopic brain lesions were noted, but multifocal dissemination of neoplastic
epithelial cells to the leptomeninges was observed histologically.
Several pathways by which neoplastic cells can reach the meninges have been suggested and haematogenous dissemination was considered most likely in these cats. Squamous cell carcinoma is the most common cutaneous malignant neoplasm in cats and meningeal carcinomatosis can be considered a rare complication
Experimental studies using pulsed electromagnetic fields on rats with vascular, cutaneous and peripheral nerves lesions
No full textExperimental studies using pulsed electromagnetic fields on rats with vascular, cutaneous and peripheral nerves lesion
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