1,721,186 research outputs found

    Cutaneous Mastocytosis Exacerbated by Pinworms in a Young Boy

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    Cutaneous mastocytosis in children has an indolent course and undergoes spontaneous regression. Many triggering factors may cause mast cell degranulation and clinical manifestations. Knowledge of these factors is important for patients and their families. We report a case of exacerbation of urticaria pigmentosa due to mast cell degranulation caused by Enterobius vermicularis, which has not been reported before as a triggering factor

    Subcutaneous fistula in infancy: a different diagnosis of a perianal discharging nodule

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    Fistula-in-ano (FIA) is an abnormal communication between the anal canal and the perianal skin with an external exit hole draining spontaneously. In FIA the fistulous tract starts from a deep acute purulent inflammation of the anal region, usually an abscess. Perianal abscess (PA) generally arises from the acute infection of a small gland just inside the anus due to the entry of bacteria or foreign material in the gland. In the first year of life PA and FIA are associated and, in contrast to other age groups, in infants they seem to have mainly a malformative origin, without the presence of an underlying concomitant disease. PA is normally the forerunner sign of FIA while it is exceptional to find FIA alone. We present here the case of a 8-month-old boy with a superficial subcutaneous fistula-in-ano unpreceded by PA. Pathogenesis and management are reported as well as a review of the literature

    Short anagen syndrome: A case series and algorithm for diagnosis.

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    Background: The short anagen syndrome (SAS) is a rare idiopathic pediatric disorder characterized by the short duration of the anagen phase. SAS mainly affects Caucasian children. Parents complain of their child's inability to grow long hair. Topical minoxidil may be an effective treatment for SAS; however, a slow spontaneous improvement is typical. Objective: Our aim was to collect data on out cases of SAS and create an algorithm to facilitate diagnosis of SAS. Methods: A retrospective review of 25 patients with SAS was performed within the Dermatology Department of the University of Bologna. We collected data regarding symptoms, pull test, hair card test, trichoscopy, trichogram, treatments, including biotin and minoxidil, and clinical outcome. Results: Characteristic findings included parental reporting that the hair had not required a haircut, hair card test showing hairs with conical-shaped tips, and hair shafts of different diameters, with more 10%-20% of hair shafts less than 60 μm thick on trichoscopy. Trichogram revealed an increased percentage of telogen hair with normal hair shafts and tapering ends. The mean anagen-to- telogen ratio was 66:34 (normal ratio 90:10). Conclusion: We developed an algorithm to facilitate the diagnosis of this rare hair disease using clinical examination and invasive and non-invasive testing to differentiate SAS from other forms of pediatric alopecia. In conclusion, the collected data of the therapy showed that biotin alone or in combination with topical minoxidil is an effective treatment for SAS
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