350 research outputs found
"Si tout sujet est portrait” : figurations du moi dans Le Monde désert de Jouve et La Mort difficile de Crevel
No full textThe analysis of two novels from the 1920s selected as emblematic cases – Le Monde désert by Jouve and La Mort difficile by Crevel – leads the author to point out the connections between the figuration of the subject in literature and the portrait in painting. Indeed, the survival of the portrait itself as a pictorial genre can be seen as a sign of its involvement in the enquiry of identity and subjectivity. This article describes the three main axes that organise subjectivity as a portrait: the fluctuation between stasis and movement, the relational dimension and the fictional one. The portrait becomes the ideal model of a subject conceived as the result of a creative process. Hence, painting is not to be considered a mere narrative theme but a key to the interpretation of the novels and a metaphor of the construction of the subject
The second hit of DNA methylation
No full textGene expression programs are tightly regulated by heritable "epigenetic" information, which is stored as chemical modifications of histones and DNA. With the recent development of sequencing-based epigenome mapping technologies and cancer cellular reprogramming, the tools are now in hand to analyze the epigenetic contribution to human cancer
Multiple sclerosis: getting personal with induced pluripotent stem cells
No full textHuman induced pluripotent stem (iPS) cells can be derived from lineage-restricted cells and represent an important tool to develop novel patient-specific cell therapies and research models for inherited and acquired diseases. Recently, patient-derived iPS cells, containing donor genetic background, have offered a breakthrough approach to study human genetics of neurodegenerative diseases. By offering an unlimited source of patient-specific disease-relevant cells, iPS cells hold great promise for understanding disease mechanisms, identifying molecular targets and developing phenotypic screens for drug discovery. This review will discuss the potential impact of using iPS cell-derived models in multiple sclerosis (MS) research and highlight some of the current challenges and prospective for generating novel therapeutic treatments for MS patients.Version of Recor
«Una strania fenice». Marco Santagata: gli studi, le opere
No full textIl libro raccoglie contributi sulla figura e le opere di Marco Santagata, italianista e scrittore. Ne sono autori Annalisa Andreoni, Gian Mario Anselmi, Gabriele Baldassari, Roberto Barbolini, Pietro G. Beltrami, Claudia Berra, Alberto Bertoni, Laura Bosio, Cristiana Brunelli, Alberto Casadei, Roberta Cella, Michele Feo, Francesco Ferretti, Gianfranco Fioravanti, Serena Fornasiero, Christian Genetelli, Klaus W. Hempfer, Giuseppe Indizio, Vincenzo Manca, Grazia Melli, Cristina Montagnani, Matteo Palumbo, Laura Paolino, Diego Quaglioni, Amedeo Quondam, Gerhard Regn, Laura Regnicoli, Francisco Rico, Raffaele Ruggiero, Gino Ruozzi, Salvatore Settis, Silvana Tamiozzo, Chiara Tognarelli, Paola Vecchi Galli, Tiziano Zanato. Chiude il volume la Bibliografia degli scritti di Marco Santagata.
Marco Santagata (Zocca, 28 aprile 1947 ‒ Pisa, 9 novembre 2020) è stato studioso di letteratura italiana e romanziere. A lungo docente all’Università di Pisa, è autore di studi fondamentali su Petrarca – culminati nel commento al Canzoniere (1996, 20042) –, su Dante, Boccaccio, la poesia del Quattrocento e Boiardo, e sulla tradizione lirica fino a Leopardi, Pascoli e d’Annunzio. A ciò ha affiancato una felice produzione narrativa: tra i suoi romanzi Il copista (2000), Il maestro dei santi pallidi (2002, Premio Campiello 2003), L'amore in sé (2006, Premio Stresa), Come donna innamorata (2015, finalista al Premio Strega). La sua poliedrica natura di intellettuale impegnato e curioso del mondo lo ha portato anche ad occuparsi attivamente di politica culturale e universitaria e di divulgazione.The book collects contributions on the figure and works of Marco Santagata, scholar of Italian literature and novelist. The authors are Annalisa Andreoni, Gian Mario Anselmi, Gabriele Baldassari, Roberto Barbolini, Pietro G. Beltrami, Claudia Berra, Alberto Bertoni, Laura Bosio, Cristiana Brunelli, Alberto Casadei, Roberta Cella, Michele Feo, Francesco Ferretti, Gianfranco Fioravanti, Serena Fornasiero, Christian Genetelli, Klaus W. Hempfer, Giuseppe Indizio, Vincenzo Manca, Grazia Melli, Cristina Montagnani, Matteo Palumbo, Laura Paolino, Diego Quaglioni, Amedeo Quondam, Gerhard Regn, Laura Regnicoli, Francisco Rico, Raffaele Ruggiero, Gino Ruozzi, Salvatore Settis, Silvana Tamiozzo, Chiara Tognarelli, Paola Vecchi Galli, Tiziano Zanato. The volume closes with the Bibliography of Marco Santagata's writings.
Marco Santagata (Zocca (Modena), 28 April 1947 ‒ Pisa, 9 November 2020) was a scholar of Italian literature and novelist. Long a professor at the University of Pisa, he is the author of fundamental studies on Petrarch - culminating in the commentary on the "Canzoniere" (1996, 20042) -, on Dante, Boccaccio, fifteenth-century poetry and Boiardo, and on the lyric tradition up to Leopardi, Pascoli and d'Annunzio. Alongside this he has a successful narrative production: among his novels "Il copista" (2000), "Il maestro dei santi pallidi" (2002, Campiello Prize 2003), "L'amore in sé" (2006, Stresa Prize), "Come donna innamorata" (2015, finalist for the Strega Prize). His multifaceted nature as a engaged intellectual has also led him to actively deal with cultural and university politics and dissemination
CORRIGENDUM to The mechanisms of acute interstitial nephritis in the era of immune checkpoint inhibitors in melanoma
No full textIn this article, the authors’ first names and surnames were incorrectly listed in the wrong order. The correct author list is: Marco Tucci, Anna Passarelli, Annalisa Todisco, Francesco Mannavola, Luigia Stefania Stucci, Stella D’Oronzo, Michele Rossini, Marco Taurisano, Loreto Gesualdo and Franco Silvestris
The Climate Show:Episode 27: Conceptualizing just transition litigation
No full textIn this episode, Assistant Professor Linnéa Nordlander speaks to Professor Annalisa Savaresi from the University of Eastern Finland about the phenomenon of just transition litigation. The episode focuses on the article ‘Conceptualizing just transition litigation’, published in Nature Sustainability, of which Professor Savaresi is the lead author and Linnéa Nordlander is among the co-authors
Storie postcoloniali
No full textan essay on the rewriting of history in the work of postcolonial author
Induced pluripotent stem cells in hematology: current and future applications
No full textReprogramming somatic cells into induced pluripotent stem (iPS) cells is nowadays approaching effectiveness and clinical grade. Potential uses of this technology include predictive toxicology, drug screening, pathogenetic studies and transplantation. Here, we review the basis of current iPS cell technology and potential applications in hematology, ranging from disease modeling of congenital and acquired hemopathies to hematopoietic stem and other blood cell transplantation.Version of Recor
THE ROLE OF THE FIRM IN FIGHTING POVERTY DURING THE PANDEMIC: THE ITALIAN SYNERGY OF BARILLA-CARITAS
No full textThe aim of this research is to study firms as a means of distribution, and not only of production, of wealth. In crisis and emergency situations, such as the one caused by the COVID-19 pandemic,
a particularly serious problem of growing and widespread poverty emerges. The author believes that
in these situations the ethical function of firms becomes central. This function can be carried out effectively not only through the efficient management of the firm, but also through ethical actions, as the
creation of alliances and synergies between businesses and the Church, which help the processes of
distribution of wealth in society, in general, and in the weaker social classes in particular
Ruling minorities within groups of companies and their problems: Proposals from the European literature, 1776-1976
No full textThe author aims to find the systematic causal links between majorities and
minorities, especially to demonstrate how, even as corporate governance systems change, the same links remained unchanged, at least starting from the
original forms of limited liability (colonial) companies. The main cause of the
oppression of minorities lies in the power of control, which instead of belonging
to the majority of share capital holders, is held by close minority shareholders.
For this purpose, the author presents a historical reconstruction of the problem
concerning the balance of powers between dominant minorities and disjoint
majorities within the groups of companies
- …
