1,720,962 research outputs found

    Continuous combined HRT in post-menopause: two regimen comparative study

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    Continuous combined HRT in post-menopause: two regimen comparative study U. Omodei, F. Sorgi, A. Torri and AM Boccuti Department of Obstetrics and Gynecology, University of Brescia, Italy Introduction A large body of evidence has accumulated concerning the positive benefits of estrogen treatment, including a decreased incidence of osteoporosis, vasomotor symptomathology, and relative risk of chardiovascular disease (CHD)

    A New HRT Regimen Using Estradiol Valerate and Cyproterone Acetate: Impact on Lipid Metabolism

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    We evaluated a new sequential HRT regimen (Climen‐Schering) consisting of a combination of estradiol valerate (2 mg, days 1‐11) and cyproterone acetate (CPA: 1 mg) plus estradiol valerate (2 mg, days 12‐21) followed by a 7‐day interval with no drug intake. The interesting aspect of this regimen is the use of CPA. a strong progestogen with antiandrogenic properties. For this reason, CPA is expected not to counteract the favourable estrogen impact on lipids

    A New HRT Regimen Using Estradiol Valerate and Cyproterone Acetate: Clinical Data

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    A new sequential HRT regimen (Climen‐Schering) consisting of a combination of estradiol valerate (EV)(2 mg. days 1‐11) and cyproterone acetate (CPA; 1 mg) plus EV (2 mg, days 12‐ 21) followed by a 7‐day drug‐free interval was tested, The interesting aspect of this regimen is the use of CPA, a strong progestogen with antiandrogenic properties

    Doppler flow evaluation of endometrial conditions in postmenopausal breast cancer patients treated with tamoxifen

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    The aim of the study was to evaluate the usefulness of Doppler flow ultrasonography in the evaluation of 88 postmenopausal breast cancer patients treated with tamoxifen (20 mg/day for at least 1 year). Twenty healthy postmenopausal women served as controls. The PI and RI (mean+/-SD) in the tamoxifen group (1, 77+/-0, 47 and 0, 79+/-0, 1, respectively) were significantly lower than those of the control group (2, 64+/-0, 8 and 0, 92+/- 0, 1, respectively)

    Endometrial changes in postmenopausal breast cancer patients receiving tamoxifen: a transvaginal ultrasound study

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    Abstract: The purpose of the study was to evaluate the effects of tamoxifen therapy on the endometrium by transvaginal sonography. Seventy-nine asymptomatic postmenopausal women treated with tamoxifen (20 mg/day) for at least one year were recruited. Twenty healthy postmenopausal women served as controls. All patients underwent transvaginal ultrasound to evaluate endometrial thickness and echotexture

    Endometrial ultrasound transvaginal (TVU) assessment in postmenopausal women on hormone replacement therapy (HRT)

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    There are only fragmentary data about TVU assessment in postmenopausal women on HRT, but usually an endometrial thickness (ET)< 4mm (as for postmenopausal women not on HRT) seems adequate to exclude the presence of endometrial pathology. The aim of our study was to evaluate the TVU effectiveness compared with hysteroscopy (HSG) plus endometrial biopsy to identify endometrial alterations, and to find a cut-off value under which invasive techniques are useless

    The effect of HRT on uterine arterial blood flow in postmenopausal women assessed by transvaginal color doppler sonography (TVDS)

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    HRT has been suggested to have neither a metabolic nor a direct vascular effect on arterial tone. PI and RI are indicators of resistance to flow: the higher the value of these indices, the greater the resistance to flow. The TVDS measurements of uterine blood flow in postmenopausal women (pmw) show a mean uterine artery PI of 3.3+/-1.04 and a mean RI of 0.93+/-0.1. The aim of our study was to determine whether HRT had any positive effect on uterine arterial blood flow. 96 pmw consented to enter the study

    The Effect of HRT on Endometrial Thickness (ET) and Uterine Arterial Blood Flow Assessed by Transvaginal Ultrasound (TVU).

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    The aim of our study was to evaluate the TVU effectiveness compared to hysteroscopy plus endometrial biopsy (HS/B) to identity endometrial alterations and to find a cut‐off value under which invasive techniques are useless; furthermore, we aimed to determine whether HRT had any positive effect on uterine arterial blood flow, 96 postmenopausal women (pmw) consented to enter the study. Patients*(pts) mean age was 56.1 years. with menopausal amenorrhoea for at least 9 months and on HRT for at least 6 month
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