212 research outputs found

    Sulla negazione nel "Tristano e Isotta" di Thomas tra grammatica e retorica

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    The essay explores the negation system in the Tristan of Thomas, which grammatical and lexical processes Thomas uses to realize the negation idea. The verses of the romance are inlaid of negative phrases that exploit parallelisms and antithesis to broaden their significance. The large use of negative expressions, that are often employed in the most emphatic variant, is strictly linked with the rhetoric component of the text and becomes thicker in the interior monologues and in the comments of the author, whereas it is much less significant in the narrative parts or in the dialogues. Almost a linguistic tic of Thomas is the extraordinary frequent use of exclusive-restrictive negation phrases. Their nature allow to better adhere to the repercussions that each episode has in the interiority of the characters, they follow the spread of a sentiment in thousands of different facets and reflect the instability of the passion

    Management of Oral Hydroxyurea-Related Ulcers: A Cases Series

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    Hydroxyurea (HU) is an anti-cancer agent commonly used in myeloproliferative Philadelphia negative disorders as polycythemia vera (PV), essential thrombocitosis (ET) and myelofibrosis (MF). [...

    Conservative Approach in Patients with Pemphigus Gingival Vulgaris: A Pilot Study of Five Cases

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    Objectives. The aim of this pilot study was to describe the clinical efficacy of a conservative oral hygiene protocol in patients affected by gingival pemphigus vulgaris (PV) applied in a case series. Methods. Subjects suffering from PV with gingival localisation and slightly responsive to conventional treatment with systemic corticosteroids and immunosuppressive drugs were selected among individuals treated in the Unit of Oral Medicine Section of the University of Turin. Five subjects received nonsurgical periodontal therapy, over a 7-day period, including oral hygiene instructions; patients were instructed about domiciliary oral hygiene maintenance and instructions were reinforced at each visit and personalised if necessary. Clinical outcome variables were recorded at baseline (before starting) and 16 weeks after intervention, including full mouth plaque score (FMPS), bleeding scores (FMBS), probing pocket depth (PPD), oral pemphigus clinical score (OPCS), and patient related outcomes (visual analogue score of pain). Results. Five patients were treated and, after finishing the proposed therapy protocol, a statistical significant reduction was observed for FMBS (P=0.043) and OPCS (P=0.038). Conclusions. Professional oral hygiene procedures with nonsurgical therapy are related to an improvement of gingival status and a decrease of gingival bleeding in patients affected by PV with specific gingival localization

    Treatment of angular cheilitis: a narrative review and authors' clinical experience

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    Angular cheilitis (AC) is a clinical entity first described in the XIX century, characterized by erythema, rhagades, ulcerations, and crusting of one or both lip commissures and perilabial skin, responsible of an unpleasant and painful discomfort. Aim of this manuscript was to examine and evaluate the therapeutic options actually available for AC. Despite antifungals being the first-line treatment for most of clinicians, very limited scientific evidence supports their reliability, with just two RCTs published between the '70s and the '80s. Furthermore, alternative topical treatments, various techniques of occlusal vertical dimension restoration, B-vitamin supplementation, anti-drooling prosthetic device and photodynamic therapy have been experimented and proposed, mostly in the form of case reports or case-series on a small number of individuals. Our group found in 1% isoconazole nitrate (ISN) and 0.1% diflucortolone valerate (DFV) ointment the most consistent AC treatment, due to the broad spectrum of ISN against many species of dermatohpytes and bacteria, and the anti-inflammatory properties displayed by DFV. However, further and well-designed trials on larger samples of patients are needed to assess the differential profile of consistency of the treatments outlined in literature and claimed by the Authors of this paper. This article is protected by copyright. All rights reserved
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