3,749 research outputs found
The Early Memoirs of Howard Simpson
The Early Memoirs of Howard Simpson, life in early twentieth century Texas and New Mexico. An account of his childhood and family’s beginnings in West Texas and their journey into western New Mexico and Arizona during the pre-depression era
Author Dorothy Simpson Beimer at Valmora
Author Dorothy Simpson Beimer standing outdoors at Valmora
Harriette Simpson Arnow, 1908-1986
A documentary film on southern Appalachian author Harriette Simpson Arnow. Directed by Herb E. Smith for Appalshop Productions in 1987
Carl H. Gellenthien, M.D. and Author Dorothy Simpson Beimer
Dr. Gellenthien and author Dorothy Simpson Beimer in the library at Valmora in November, 1984
Carl H. Gellenthien, M.D. and Author Dorothy Simpson Beimer
Dr. Gellenthien and author Dorothy Simpson Beimer in the library at Valmora in November, 1984
Carl H. Gellenthien, M.D. and Author Dorothy Simpson Beimer
Dr. Gellenthien and author Dorothy Simpson Beimer in the library at Valmora in November, 1984
Carl H.Gellenthien, M.D. and Author Dorothy Simpson Beimer
Dr. Gellenthien and author Dorothy Simpson Beimer at Valmora in November, 1984
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Mona Simpson: Q&A with the Bestselling Novelist and Professor of English
Mona Simpson writes novels. Her 1987 debut, Anywhere But Here, follows Adele and Ann August, a mother and daughter who move from the Midwest to Los Angeles in search of a less ordinary life. The novel went on to be a national bestseller, winning the Whiting Award in 1986, catapulting the author into the literary spotlight. Simpson followed her first novel’s success with a sequel: The Lost Father, published in 1992. Four years later, Simpson returned with A Regular Guy (1996). That same year Granta named Simpson one of America’s Best Young Novelists. In 2000, Simpson published Off Keck Road, a novel about a small town spinster, a man who has always been in her life, and a young girl, who completes the odd triangle. This work was a finalist for the PEN/Faulkner Award. Her upcoming novel, My Hollywood (Knopf, Spring 2010), depicts the upstairs/downstairs ironies, enmities, and strange affections between a community of immigrant nannies and their employers in contemporary Los Angeles. Presently, Simpson has begun a story about the lives and loves of Diaspora Arabs in Europe, the Gulf, and the United States, and of their more assimilated, half-American cousins. Simpson is also a Professor in the Department of English and plays an active part in organizing the Friends of English and Hammer Museum’s popular “Some Favorite Writers” series. On a recent summer afternoon, I sat down in a Brentwood coffee shop with Simpson to talk about her work and, in particular, The American Cousins
Optimising the detection of transient evoked potentials using a bootstrap re-sampling technique to provide an objective measure of signal recovery
Introduction: Most commonly, the estimation of transient evoked potentials such as the ERG, PERG and VEP is by simple ensemble averaging, synchronized by the stimulation signal. This requires three assumptions: (i) the signal to be recovered is stationary; (ii) the noise (or ‘incoherent’ signal component) is stationary with zero mean; (iii) the number of epochs sampled is sufficient to statistically represent the signal of interest within acceptable confidence limits. Whilst ensemble averaging still forms the cornerstone of transient evoked potential measurement, it does not exploit modern statistical signal processing techniques and the potential for extracting more statistical information from the recorded signals. Purpose: To describe a statistical bootstrap method that provides an estimate of the probability that the response obtained is due to random variation in the data rather than a physiological response (viz., the null hypothesis). This method can be applied to (almost) any signal parameter (e.g., power, amplitude range, estimates of signal-to-noise ratio) and is based on randomly re-sampling (with replacement) of the continuously recorded data. Method: The proposed method was developed and tested initially on simulated data with realistic autoregressive moving average (ARMA) noise. This was extended to a series of clinical PERG recordings. Results: The bootstrap model was able to detect the presence of PERG responses at user-defined significance levels in both artificial and clinical recordings. Conclusion: The bootstrap re-sampling technique is simple to implement, very flexible in terms of the signal features that can be statistically analysed, and provides a novel means of objectively testing signal recovery. It thus holds the potential to optimize the acquisition process, and to determine the shortest recording time required, based on a clearly defined statistical criterion
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