52 research outputs found

    Concept and development of an autonomous wearable micro-fluidic platform for real time pH sweat analysis

    No full text
    In this work the development of an autonomous, robust and wearable micro-fluidic platform capable of performing on-line analysis of pH in sweat is discussed. Through the means of an optical detection system based on a surface mount light emitting diode (SMD LED) and a light photo sensor as a detector, a wearable system was achieved in which real-time monitoring of sweat pH was performed during 55 minutes of cycling activity. We have shown how through systems engineering, integrating miniaturised electrical components, and by improving the micro-fluidic chip characteristics, the wearability, reliability and performance of the micro-fluidic platform was significantly improved

    Intensification of the students' self-development process when performing design and settlement works on the "machine parts" course

    No full text
    © by The Author(s). The article addresses issues related to the methodology of intensifying self-development process when performing t design and settlement works on the "Machine Parts" course for the students studying in such areas of training as "Technology" and "Vocational Education" with the use of computer technologies. At the same time, there are formulated the required pedagogical conditions that must be provided to all participants of the educational process, and accordingly, there are disclosed methodological aspects of the design and settlement work performance by means of specialized computer software. This in turn makes it possible to intensify the students' self-development process during the study of the "Machine parts" course. To succeed in the intensification of the students' self-development process when performing design and settlement works on the "Machine Parts" course, there should be develop appropriate pedagogical conditions. The most effective implementation of this methodology may be performed through the usage of specialized computer software. There is provided a technology of designing two-stage parallel-shaft reduction gear unit based on specialized computer software Compass 3D. Implementation of specialized computer software when performing a course project on "Machine Parts" allows intensifying the self-development quality of students within the educational process

    Intensification of the students' self-development process when performing design and settlement works on the "machine parts" course

    No full text
    © by The Author(s). The article addresses issues related to the methodology of intensifying self-development process when performing t design and settlement works on the "Machine Parts" course for the students studying in such areas of training as "Technology" and "Vocational Education" with the use of computer technologies. At the same time, there are formulated the required pedagogical conditions that must be provided to all participants of the educational process, and accordingly, there are disclosed methodological aspects of the design and settlement work performance by means of specialized computer software. This in turn makes it possible to intensify the students' self-development process during the study of the "Machine parts" course. To succeed in the intensification of the students' self-development process when performing design and settlement works on the "Machine Parts" course, there should be develop appropriate pedagogical conditions. The most effective implementation of this methodology may be performed through the usage of specialized computer software. There is provided a technology of designing two-stage parallel-shaft reduction gear unit based on specialized computer software Compass 3D. Implementation of specialized computer software when performing a course project on "Machine Parts" allows intensifying the self-development quality of students within the educational process

    FIBEROPTIC TRACHEA INTUBATION

    No full text
    The article presents the analysis of the existing literature on the use of fiberoptic facilities during challenging tracheal intubation. Awake fiberoptic intubation is the «gold standard» for difficult intubation cases in selective surgery. However, in emergency cases there is no clear rule for particular fiberoptic bronchoscope intubation method (awake, under anaesthesia with neuroomuscular relaxants or without them). Moreover, fiberoptic bronchoscope intubation technique is not described and valid enough. This is why further shared and generalized experience of fiberoptic tracheal intubation is needed, primarily for anesthetic management of emergency operations

    ACTUAL SURGICAL TREATMENT OF DILATED CARDIOMYOPATHY

    No full text
    The high mortality and morbidity of patients in terminal heart failure are a therapeutic challenge to modern medicine. Surgically, cardiac transplantation is an excellent treatment for many patients. However, lack of donors combined with an increasing number of patients has led to the search for other surgical strategies. Although other common surgical methods’, such as Batista operation or dynamic cardiac myoplasty has a favorable outcome in selected patients, those method’s is currently not recommended for treatment of heart failure because of high surgical failure rates. The present paper reviews some of the relevant literature regarding surgical left ventricular remodeling in heart failure

    Dynamic Reservoir-Pressure Maintenance System Study in Carbonate Reservoir with Complicated Pore Structure by Production Analysis, Production Logging and Well-Testing

    No full text
    Abstract To discover remained reserves and recommend production enhancement operations in a carbonate reservoir with long production history it is important to perform not only production analysis, water breakthrough areas, but also areas, that took a lot of injected water during injection history. It's not an easy task in case of complicated formation pore structure especially than injection were carried on with high pressures and overbalancing. Combined approach was used for remained reserves localization and production enhancement operations. It included complex geology study, production history and surveillance data. Well interference was examined by novel technology - multi-well deconvolution (MWD).</jats:p

    Analysis of Engineered Nanoparticles in Seawater Using ICP-MS-Based Technology: From Negative to Positive Samples

    No full text
    A growing global emission of engineered nanoparticles (ENPs) into the aquatic environment has become an emerging safety concern that requires methods capable of identifying the occurrence and possibly determining the amounts of ENPs. In this study, we employed sector-field inductively coupled mass spectrometry to assess the presence of ENPs in coastal seawater samples collected from the Black Sea in regions suffering different anthropogenic impacts. Ultrafiltration through commercial 3 kDa membrane filters was shown to be feasible to separate the ENPs from the bulk seawater, and the subsequent ultrasound-mediated acidic dissolution makes the metals constituting the ENPs amenable to analysis. This procedure allowed the ENPs bearing Cu, Zn, V, Mo, and Sn to be for the first time quantitated in seashore surface water, their concentration ranging from 0.1 to 1.0 &mu;g L&minus;1 (as metal) and related to the presence of industry and/or urban stress. While these levels are decreased by natural dilution and possible sedimentation, the monitored ENPs remain measurable at a distance of 2 km from the coast. This can be attributed not only to local emission sources but also to some natural backgrounds

    Structure-activity relationships for NAMI-A-type complexes (HL)[trans-RuCl4L(S-dmso)ruthenate(III)] (L = imidazole, indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole): Aquation, redox properties, protein binding, and antiproliferative activity

    No full text
    Imidazolium [trans-tetrachloro(1H-imidazole)(S-dimethylsulfoxide) ruthenate(III)] (NAMI-A) and indazolium [trans-tetrachlorobis(1H-indazole) ruthenate(III)] (KP1019) are the most promising ruthenium complexes for anticancer chemotherapy. In this study, the azole ligand of NAMI-A was systematically varied (from imidazole of NAMI-A to indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole), and the respective complexes were evaluated with regard to the rate of aquation and protein binding, redox potentials, and cytotoxicity by means of capillary zone electrophoresis, electrospray ionization mass spectrometry, cyclic voltammetry, and colorimetric microculture assays. Stability studies demonstrated low stability of the complexes at pH 7.4 and 37 °C and a high reactivity toward proteins (binding rate constants in the ranges of 0.02-0.34 and 0.01-0.26 min-1 for albumin and transferrin, respectively). The redox potentials (between 0.25 and 0.35 V) were found to be biologically accessible for activation of the complexes in the tumor, and the indazole-containing compound shows the highest antiproliferative activity in vitro. © 2007 American Chemical Society
    corecore