144 research outputs found
NEW APPROACH IN URTICARIA TREATMENT
No full textThe article presents the European Guidelines for the Diagnostics and Management of Urticaria (revised in 2013) and new data on the physiopathology of urticaria related to the role of the platelet-activating factor (PAF) activating mast cells, attracting eosinophils and neutrophils, improving vascular permeability (it is more potent than histamine by 1,000 times) and mucosal edema, and increasing the level of pro-inflammatory cytokines. The data promoted the creation of a new rupatadine molecule, which blocks histamine and PAF receptors at the same time improving the therapeutic effect during urticaria treatment as compared to other antihistamine drugs. The author presents the study results confirming the efficacy and safety of rupatadine
Топическая терапия пиодермий
No full textThe article is of an overview nature. It provides various classifications of pyoderma and infections of the skin and soft tissues, epidemiological data on pyoderma in our country and abroad, discusses in detail local and systemic risk factors for the development of the disease, environmental risk factors. Much attention is paid to comparative studies on the efficacy and safety of mupirocin (Supirocin) in comparison with systemic antibiotics and topical antibacterial agents, indicating the benefits of mupirocin.Статья носит обзорный характер. Приводятся различные классификации пиодермий и инфекций кожи и мягких тканей, эпидемиологические данные о пиодермиях в нашей стране и за рубежом, подробно рассматриваются локальные и системные факторы риска развития заболевания, факторы риска окружающей среды. Большое внимание уделяется сравнительным исследованиям по эффективности и безопасности применения мупироцина (Супироцина) в сравнении с системными антибиотиками и топическими антибактериальными средствами, свидетельствующим о преимуществе мупироцина
To the question of the effect of isotretinoin on the neuropsychic state of patients with acne
No full textPatients with acne often develop neuropsychiatric disorders of varying severity, correlating, as a rule, with the severity of dermatosis. Isotretinoin is the most commonly used drug for the treatment of moderate acne. Due to the fact that in a number of studies isotretinoin was considered as a trigger for the development of various neuropsychiatric disorders, numerous studies were conducted to prove this possibility or to refute it. An analysis of the literature showed that, according to the vast majority of studies, isotretinoin does not lead to neuropsychiatric disorders. However, given the opposite opinion of some authors, it is advisable to actively identify, including in the anamnesis, any psycho-emotional disorders, and monitor them during therapy. In these cases, it is indicated to start treatment with small doses (recommendations have not been developed)
Modern approaches to the treatment of chronic urticaria
No full textThe article provides modern definitions and classification of urticaria. The general provisions of the treatment of chronic urticaria, the treatment of which is often very difficult, are outlined. The main provisions of the treatment of urticaria were formulated, according to which the patient should be treated until the rash is completely resolved. In chronic urticaria, it is necessary to identify and eliminate the causes of dermatosis; avoid exposure to identified triggers; increase tolerance; pharmacological treatment should be aimed at preventing the release of mast cell mediators and/or the effects of mast cell mediators. The goal of treatment should be to relieve the symptoms of urticaria as completely as possible, taking into account the safety and quality of life of the patient in each individual case. The importance of identifying and addressing underlying causes and avoiding identified triggers is emphasized. The therapy algorithm is considered in detail, including 4 lines according to the European guidelines and domestic clinical guidelines. Particular attention is paid to the treatment of various subtypes of chronic urticaria. A comparative description of the most effective antihistamines is given
Technical Physics V. 45, I. 07
No full textTechnical Physics -- July 2000
Volume 45, Issue 7, pp. 813-954
THEORETICAL AND MATHEMATICAL PHYSICS
Theory of Cyclotron Superradiance from a Moving Electron Bunch under Group Synchronism Conditions
N. S. Ginzburg, I. V. Zotova, and A. S. Sergeev
pp. 813-820 Full Text: PDF (94 kB)
The Classification of Anisotropic Stressed States in Spherical Bodies
A. S. Baranov
pp. 821-825 Full Text: PDF (60 kB)
Relativistic Particle in a Traveling Magnetic Field
A. I. Toropova
pp. 826-830 Full Text: PDF (64 kB)
ATOMS, SPECTRA, AND RADIATION
Electromagnetic Transitions between Rydberg States of a Hydrogen Atom: Violation of the Dipole Selection Rules in a Strong Field
O. B. Prepelitsa
pp. 831-835 Full Text: PDF (59 kB)
Positron Scattering by Phonons in Metals
D. A. Gryaznykh
pp. 836-839 Full Text: PDF (59 kB)
GASES AND LIQUIDS
Instability of a Charged Spherical Viscous Drop Moving Relative to a Medium
A. I. Grigor'ev, V. A. Koromyslov, and S. O. Shiryaeva
pp. 840-848 Full Text: PDF (106 kB)
SOLIDS
Phase-Transition Radiation and the Growth of a New Phase
S. A. Sall' and A. P. Smirnov
pp. 849-853 Full Text: PDF (55 kB)
On the Turbulization of the Viscocrystalline Phase
S. O. Gladkov
pp. 854-857 Full Text: PDF (56 kB)
OPTICS, QUANTUM ELECTRONICS
Short-Laser-Pulse-Induced Photoelectric Phenomena and Reorientation in Nematics Activated with Ionic Dyes
S. V. Serak, A. A. Kovalev, and A. V. Agashkov
pp. 858-864 Full Text: PDF (108 kB)
Analogs of the Brewster Effect and Total Internal Reflection for Cylindrical Waves
M. A. Kaliteevskii and V. V. Nikolaev
pp. 865-869 Full Text: PDF (62 kB)
Evolution of the Glow of an Aerogel Irradiated with a High-Power Pulse Electron Beam
B. A. Demidov, V. P. Efremov, M. V. Ivkin, I. A. Ivonin, V. A. Petrov, and V. E. Fortov
pp. 870-877 Full Text: PDF (329 kB)
On the Theory of Space–Time Polarization Holography
B. N. Kilosanidze and E. Sh. Kakichashvili
pp. 878-882 Full Text: PDF (62 kB)
RADIOPHYSICS
Relativistic Microwave Devices with Postacceleration of an Electron Beam in the Interaction Space
É. B. Abubakirov and A. V. Savel'ev
pp. 883-886 Full Text: PDF (52 kB)
ELECTRON AND ION BEAMS, ACCELERATORS
Dispersion Dilution of the Beam Emittance in Linear High-Energy Electron Accelerators
V. M. Tsakanov
pp. 887-895 Full Text: PDF (113 kB)
Dynamical Chaos in a Charged-Particle Flow Produced by a Magnetron Injection Gun: Numerical Simulation and Experiment
Yu. A. Kalinin, V. N. Kozhevnikov, A. G. Lazerson, G. I. Aleksandrov, and E. E. Zhelezovskii
pp. 896-904 Full Text: PDF (277 kB)
SURFACES, ELECTRON AND ION EMISSION
Effect of Thermal Annealing on Spectral Properties of Electrodeposited Carbon Films
V. P. Dymont, M. P. Samtsov, and E. M. Nekrashevich
pp. 905-908 Full Text: PDF (75 kB)
Deformation of the Contact Area and Adhesive Friction between a Scanning Frictional Microscope Probe and the Atomic-Flat Surface
G. V. Dedkov and M. B. Dyshekov
pp. 909-914 Full Text: PDF (76 kB)
EXPERIMENTAL INSTRUMENTS AND TECHNIQUES
Kinetics of Radiation Cooling of Fullerenes
A. A. Vostrikov, A. A. Agarkov, and D. Yu. Dubov
pp. 915-921 Full Text: PDF (110 kB)
Discharge Leader Self-Organization on the Water Surface
V. P. Belosheev
pp. 922-927 Full Text: PDF (185 kB)
Melting of Aluminum Nitride at Atmospheric Nitrogen Pressure
L. G. D'yachkov, L. A. Zhilyakov, and A. V. Kostanovskii
pp. 928-930 Full Text: PDF (40 kB)
A New Model of a Quantum Magnetometer: A Single-Cell Cs–K Tandem Based on Four-Quantum Resonance in 39K Atoms
E. B. Aleksandrov, M. V. Balabas, A. K. Vershovskii, and A. S. Pazgalev
pp. 931-936 Full Text: PDF (89 kB)
BRIEF COMMUNICATIONS
The Threshold Current of a Balanced Double-Contact Low-Inductance Interferometer
I. N. Askerzade
pp. 937-938 Full Text: PDF (28 kB)
Dependence of the Transverse Dynamics of the Plasma Electrons in the Ion Focus Regime on the Ratio of the Radius of a Relativistic Electron Beam to the Radius of the Ion Channel
E. K. Kolesnikov and A. S. Manuilov
pp. 939-941 Full Text: PDF (47 kB)
Effect of Multiple Scattering and the External Magnetic Field on the Resistive Sausage Instability of a Relativistic Electron Beam
E. K. Kolesnikov and A. S. Manuilov
pp. 942-944 Full Text: PDF (48 kB)
Cooperative Mechanism of Self-Diffusion in Metals
V. G. Chudinov
pp. 945-947 Full Text: PDF (40 kB)
On the Influence of Ionization Density in a Fast Charged Particle Track on the Light Output of Scintillations
V. K. Lyapidevskii and M. I. Ryazanov
pp. 948-949 Full Text: PDF (22 kB)
Simulation of an Early Stage of a Conductor's Electrical Explosion
S. I. Tkachenko
pp. 950-952 Full Text: PDF (40 kB)
High-Frequency Boundary for the Rayleigh–Jeans Approximation in Microwave Radiometry Problems
I. A. Semin
pp. 953-954 Full Text: PDF (27 kB)Archived web conten
New Aspects in Studies of Acne in Women
No full textThe review generalizes and summarizes new information about epidemiology, pathogenesis, diagnostics and treatment of acne in women
Features of treatment of patients with psoriasis with metabolic syndrome
No full textThe article provides information on the prevalence of metabolic syndrome in patients with psoriasis. The criteria for the diagnosis of metabolic syndrome are presented. The General mechanisms of inflam - mation development in psoriasis and diseases forming the metabolic syndrome are described. Systemic subclinical inflammatory process developing in psoriasis and metabolic syndrome is considered as the main pathogenetic mechanism of their mutual negative influence. The difficulties of treatment of patients with psoriasis with metabolic syndrome are largely associated with the choice of a safe and effective method of treatment. The description of the drug apremilast (OTEZLA®) is a selective inhibitor of the enzyme phosphodiesterase 4, which may be the best drug in the therapy of patients with psoriasis and metabolic syndrome
Topical formulations used in the treatment of acne
No full textThe article presents 2 clinical observations of patients with papules-pustular form of acne of moderate severity. In both cases the use of combined topical therapy - topical clindamycin and azelaic acid. The therapeutic effect of clindamycin is faster than other topical preparations. Azelaic acid strengthens the anti-bacterial action of clindamycin, prevents the development of resistance. The results indicate the feasibility of the combined use of these drugs in the treatment of acne
ETIOPATHOGENETIC THERAPY OF INFLAMMATORY DERMATOSES
No full textIn chronic dermatoses significantly increases the colonization of skin by bacteria and fungi, which can have a negative impact on the course of inflammatory process. Cream Candiderm is a modern combined topical drug that has anti-inflammatory, antibacterial and antifungal activity.The aim of the study was to assess the efficacy, safety and tolerability of the cream Candiderm in the treatment of patients with eczema and atopic dermatitis.Material and methods. 37 patients with AD and 28 patients with eczema. Applied cream Candiderm 2 times a day, which was applied to the affected area of the skin. Before and on the 14 day of therapy was conducted bacteriological examination of the microflora of the skin rashes.Results: at 14 days in patients with eczema remission was achieved in 17 (61 %) patients, significant improvement 6 (21 %), improvement in 4 (14 %), lack of effect in 1 (4 %); in patients with AD remission was observed in 23 (62 %) patients, significant improvement in 7 (19 %), and improvement in 5 (14 %), lack of effect in 2 (5 %).Conclusions: high clinical efficacy of the cream of Candiderm allows recommending it for topical therapy of patients with eczema and atopic dermatitis.</jats:p
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