3,743 research outputs found
Insula Studies. From Evidence to Agency. The Making of the Pompeii Sample
The relevance of insula studies to our understanding of Roman towns no longer seems to be subject to debate: since the 1970s, an increasing number of research projects and scientific publications have treated the insula as the most appropriate unit of analysis for investigating urban development and living conditions in Roman cities. This is partly because it enables an intermediate approach, bridging the gap between large- and small-scale studies. For insula-based projects, the Vesuvian sites, still a key point of reference in classical archaeology, provide a wide range of case studies. Retracing the insula-based history of the research in Pompeii allows us to outline the state of the art of the block-by-block archaeology of a Roman town. This review shows how, experience by experience, over the last 100 years the focus of the insula-based approach has shifted from built spaces towards a more holistic analysis, and it sets out a possible agenda for future research. In this agenda, due to the special nature of Pompeii, an archaeological site with a long and complex second life, a leading role is played by “alibi archaeologies”, i.e. research aimed at reassessing both older excavations (which in many cases have never been the subject of scientific publications) and the second life of unearthed material remains. Aiming to retrace older excavations and write a comprehensive history of archaeological evidence after its rediscovery, this research is indispensable for any properly holistic study of the Pompeii sample. The current and future challenge, in Pompeii and elsewhere, is to achieve a careful approach to both agency and materiality: the ultimate goal is to move from an analysis of built, decorated and furnished insulae to knowledge of what it was like to actually live in them in ancient times and what has become of them since their rediscovery.
In this regard, after revisiting the main chapters and episodes of the history of insula studies in the Pompeii sample, the paper concludes with a description of the state of the art of a project in which alibi archaeologies, as well as a focus on agency and materiality, have played a leading role. The “Pompei, Insula del Centenario (IX 8)” project has indeed adopted a comprehensive approach to insula studies since 1998: revisiting its various phases, results and objectives yet to be achieved allows us to take stock of the research agenda of a long-term and multi-dimensional project
Three-year outcomes of Straumann Bone Level SLActive dental implants in daily dental practice: a prospective non-interventional study
OBJECTIVE
The aim of this investigation was to evaluate the performance of Straumann Bone Level SLActive implants in various clinical situations in daily dental practice for up to 3 years.
METHOD AND MATERIALS
This was a prospective, multicenter, non-interventional study in which implants were placed within approved indications in any situation deemed suitable by the treating clinician. No implant placement or loading protocol was specified, and implants were placed according to the routine treatment protocols at each participating center.
RESULTS
In this analysis, data were available from 342 implants in 233 patients in three countries (USA, Canada, and Switzerland). One or two implants were placed in the majority of patients (70.8% and 19.3%, respectively), mostly in the maxilla (71.3%); almost half (47.7%) were placed in the esthetic zone. Implant placement after 4 to > 16 weeks of healing was preferred in Switzerland (92.0%), while 42.0% of implants were placed immediately in the USA and Canada. A flapless procedure was performed in 25.2% of cases in the USA and Canada, compared to 0.5% in Switzerland. Cumulative implant survival and success rates after 3 years were 97.5% and 93.5%, respectively.
CONCLUSION
Straumann Bone Level Implants can achieve favorable outcomes and high survival rates after 3 years in daily dental practice. The survival and success rates were comparable with those achieved in formal controlled clinical trials
Immediate Placement of Bone Level Straumann Implants: A Case Series
Endosseous dental implants have revolutionized the methods clinicians use to treat edentulous and partially edentulous patients. Traditional implant protocol specifies a healing period of several months after tooth extraction, as well as an unloaded healing period prior to restoration. Over the last decade, numerous studies have documented successful immediate placement of endosseous dental implants in fresh extraction sites and have found positive results with early functional loading. The purpose of this article is to present a clinical treatment protocol for the immediate placement and early loading of dental implants and to report the clinical and radiographic outcomes of the SLActive surface Straumann Bone Level implant placed in either maxillary or mandibular fresh extraction sockets. (Int J Periodontics Restorative Dent 2011;31:57-65.
Anterior Maxillary Immediate Implant Placement and Straumann Angled Solutions Restoration
This is a clinical case demonstrating placement of an immediate dental implant following the extraction of #7, a necrotic tooth with external resorption. The implant procedure was completed in two stages, then restored with an angled screw-retained Straumann crown. This crown is a new option offered by Straumann which tilts the screw channel up to thirty degrees, where otherwise a cement-retained crown would be the only esthetic and functional option
Eosinophils in the gastrointestinal tract: friends or foes?
Eosinophils play an important role in the mucosal immune system of the gastrointestinal tract under resting and under inflammatory conditions. Under steady-state conditions, the mucosa of the digestive tract is the only organ harboring a substantial number of eosinophils, which, if need be, get activated and exert several effector and immunoregulatory functions. The precise function of these late-phase inflammatory cells is not yet completely understood. Nevertheless, it has recently been demonstrated that lipopolysaccharides from gram-negative bacteria activate eosinophils to rapidly release mitochondrial DNA in the extracellular space. Released mitochondrial DNA and eosinophil granule proteins form extracellular structures able to bind and inactivate bacteria. These findings suggest a novel mechanism of eosinophil-mediated innate immune responses that might be important in maintaining the intestinal barrier function. Moreover, eosinophils also play a crucial role in several inflammatory conditions, such as intestinal infections, immune-mediated inflammations and hypersensitivity reactions. Under chronic inflammatory conditions, the ability of the eosinophils to induce repair can lead to pathological sequelae in the tissue, such as esophageal remodeling in eosinophilic esophagitis. It is established that the uncontrolled eosinophilic inflammation induces fibrosis, esophageal wall thickening and strictures leading to damage that results in a loss of esophageal function. One potential mechanism of this remodeling is so-called 'epithelial mesenchymal transition', which is triggered by eosinophils and is potentially reversible under successful anti-eosinophil treatment. Therefore, eosinophils may act either as friends or as foes, depending on the microenvironment
Cartilla práctica sobre el uso de Emdogain® (Straumann®)
Diferentes tratamientos para la periodontitis se han relacionado no solo con la resolución de la inflamación periodontal, sino también con la regeneración de los tejidos periodontales afectados. Uno de ellos se basa en el tratamiento con proteínas derivadas de la matriz del esmalte: Emdogain®, el cual está compuesto de diversas proteínas que participan en la formación del cemento en la raíz del diente en desarrollo, proporcionando una matriz de andamiaje para todos los tejidos necesarios asociados a una inserción verdaderamente funcional logrando la regeneración del periodonto: el cemento, el ligamento periodontal y el hueso alveolar. En esta guía, se dará información sobre el producto, la manera en que debe aplicarse y las referencias bibliográficas de los diferentes estudios que se han realizado corroborando su importancia en el tratamiento de la enfermedad periodontal.1. Reglamento. -- 2. Introducción. -- 3. Marco teórico. -- 4. Descripción del proceso de producción de Straumann® Emdogain®. -- 5. Indicaciones para el uso de Emdogain®. -- 6. Objetivos y materiales. -- 7. Descripción del procedimiento para usar Straumann® Emdogain®. -- 8. Estudios relacionados. -- 9. [email protected]
Pursuit responses to target steps during ongoing tracking
Brief smooth eye-velocity responses to target position steps have been reported during smooth pursuit. We investigated position-error responses in eight healthy human subjects, comparing the effects of a step-ramp change in target position when imposed on steady-state smooth pursuit, vestibuloocular reflex (VOR) slow phases, or fixation. During steadystate pursuit or VOR, the target performed a step-ramp movement in the same or in the opposite direction relative to ongoing eye movements. When the step was directed backward relative to steady-state smooth pursuit, eye velocity transiently decreased (1.3 ± 0.4°/s; average peak change in amplitude ± SD), beginning about 100 ms after the step. The amplitude of position-error responses varied inversely with the step size. In contrast, there was little or no response in trials with forward steps during steady-state smooth pursuit, when step-ramps were imposed on VOR or when smooth pursuit began from fixation. We hypothesize that during ongoing smooth tracking when a sudden shift in target position is detected the pursuit system compares the direction of ongoing eye velocity with the relative positional error on the retina. In the case of different relative directions between ongoing tracking and a new target eccentricity, a position-error response toward the new target is initiated. Such a mechanism might help the smooth pursuit system to respond better to changes in target direction. These experimental findings were simulated by a mathematical model of smooth pursuit by implementing direction-dependent behavior with a position-error gating mechanism
Propuestas de mejora de la gama de implantes Standard de Straumann
En el presente trabajo de final de grado se propone una mejora de la gama de implantes dentales Standard de la marca Straumann, uno de los implantes más comercializados de la historia de la implantología dental moderna. Para poder llevar a cabo dicha propuesta, el trabajo consta de cuatro partes, contexto histórico, análisis del implante Straumann, propuesta de un nuevo diseño y análisis comparativo de los dos implantes. En cuanto al contexto histórico, se expone el origen de la implantología dental y cómo se han ido desarrollando avances y experimentos, así cómo es el descubrimiento de la osteointegración hasta llegar a la actualidad. En la segunda parte del proyecto se analiza la gama de implantes Straumann Standard mediante un proceso exhaustivo de ingeniería inversa. Para realizar el estudio se han tenido en cuenta seis implantes, dos de cada plataforma, considerando cuatro pilares (dos rectos y dos angulados) y un tornillo. Se exponen todos los planos detallados, se efectúa un estudio de amplitud de tolerancias y se genera una base de datos. Finalmente, se analizan los casos límite donde hay mayor y menor juego. Tras este análisis se procede a proponer una serie de mejoras respecto al implante de Straumann y se diseña una nueva gama de implantes. Asimismo, se muestran planos detallados de los nuevos implantes y de los nuevos pilares, fijando un rango de tolerancias y estudiando los casos límite. Y, por último, se presenta un estudio del análisis comparativo entre los dos implantes, concluyendo que la nueva gama de implantes mejora en varios aspectos a la de Straumann
Propuestas de mejora de la gama de implantes Standard de Straumann
En el presente trabajo de final de grado se propone una mejora de la gama de implantes dentales Standard de la marca Straumann, uno de los implantes más comercializados de la historia de la implantología dental moderna. Para poder llevar a cabo dicha propuesta, el trabajo consta de cuatro partes, contexto histórico, análisis del implante Straumann, propuesta de un nuevo diseño y análisis comparativo de los dos implantes. En cuanto al contexto histórico, se expone el origen de la implantología dental y cómo se han ido desarrollando avances y experimentos, así cómo es el descubrimiento de la osteointegración hasta llegar a la actualidad. En la segunda parte del proyecto se analiza la gama de implantes Straumann Standard mediante un proceso exhaustivo de ingeniería inversa. Para realizar el estudio se han tenido en cuenta seis implantes, dos de cada plataforma, considerando cuatro pilares (dos rectos y dos angulados) y un tornillo. Se exponen todos los planos detallados, se efectúa un estudio de amplitud de tolerancias y se genera una base de datos. Finalmente, se analizan los casos límite donde hay mayor y menor juego. Tras este análisis se procede a proponer una serie de mejoras respecto al implante de Straumann y se diseña una nueva gama de implantes. Asimismo, se muestran planos detallados de los nuevos implantes y de los nuevos pilares, fijando un rango de tolerancias y estudiando los casos límite. Y, por último, se presenta un estudio del análisis comparativo entre los dos implantes, concluyendo que la nueva gama de implantes mejora en varios aspectos a la de Straumann
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