55 research outputs found
Schemes of the finite element method with separation of singularity for a two-point boundary-value problem of the 4th order with degenerate coefficients
No full textIn this paper we construct a high accuracy variant of the finite element method for an ordinary differential equation of the fourth order whose coefficients are degenerate on the boundary. The proposed technique is based on the multiplicative and additive-multiplicative separation of singularity. We prove that the convergence rate of the proposed technique is optimal in a given class of smoothness of right-hand sides. © Allerton Press, Inc., 2011
Concept and development of an autonomous wearable micro-fluidic platform for real time pH sweat analysis
No full textIn this work the development of an autonomous, robust and wearable micro-fluidic platform capable of performing on-line analysis of pH in sweat is discussed. Through the means of an optical detection system based on a surface mount light emitting diode (SMD LED) and a light photo sensor as a detector, a wearable system was achieved in which real-time monitoring of sweat pH was performed during 55 minutes of cycling activity. We have shown how through systems engineering, integrating miniaturised electrical components, and by improving the micro-fluidic chip characteristics, the wearability, reliability and performance of the micro-fluidic platform was significantly improved
Intensification of the students' self-development process when performing design and settlement works on the "machine parts" course
No full text© by The Author(s). The article addresses issues related to the methodology of intensifying self-development process when performing t design and settlement works on the "Machine Parts" course for the students studying in such areas of training as "Technology" and "Vocational Education" with the use of computer technologies. At the same time, there are formulated the required pedagogical conditions that must be provided to all participants of the educational process, and accordingly, there are disclosed methodological aspects of the design and settlement work performance by means of specialized computer software. This in turn makes it possible to intensify the students' self-development process during the study of the "Machine parts" course. To succeed in the intensification of the students' self-development process when performing design and settlement works on the "Machine Parts" course, there should be develop appropriate pedagogical conditions. The most effective implementation of this methodology may be performed through the usage of specialized computer software. There is provided a technology of designing two-stage parallel-shaft reduction gear unit based on specialized computer software Compass 3D. Implementation of specialized computer software when performing a course project on "Machine Parts" allows intensifying the self-development quality of students within the educational process
Intensification of the students' self-development process when performing design and settlement works on the "machine parts" course
No full text© by The Author(s). The article addresses issues related to the methodology of intensifying self-development process when performing t design and settlement works on the "Machine Parts" course for the students studying in such areas of training as "Technology" and "Vocational Education" with the use of computer technologies. At the same time, there are formulated the required pedagogical conditions that must be provided to all participants of the educational process, and accordingly, there are disclosed methodological aspects of the design and settlement work performance by means of specialized computer software. This in turn makes it possible to intensify the students' self-development process during the study of the "Machine parts" course. To succeed in the intensification of the students' self-development process when performing design and settlement works on the "Machine Parts" course, there should be develop appropriate pedagogical conditions. The most effective implementation of this methodology may be performed through the usage of specialized computer software. There is provided a technology of designing two-stage parallel-shaft reduction gear unit based on specialized computer software Compass 3D. Implementation of specialized computer software when performing a course project on "Machine Parts" allows intensifying the self-development quality of students within the educational process
Structure-activity relationships for NAMI-A-type complexes (HL)[trans-RuCl4L(S-dmso)ruthenate(III)] (L = imidazole, indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole): Aquation, redox properties, protein binding, and antiproliferative activity
No full textImidazolium [trans-tetrachloro(1H-imidazole)(S-dimethylsulfoxide) ruthenate(III)] (NAMI-A) and indazolium [trans-tetrachlorobis(1H-indazole) ruthenate(III)] (KP1019) are the most promising ruthenium complexes for anticancer chemotherapy. In this study, the azole ligand of NAMI-A was systematically varied (from imidazole of NAMI-A to indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole), and the respective complexes were evaluated with regard to the rate of aquation and protein binding, redox potentials, and cytotoxicity by means of capillary zone electrophoresis, electrospray ionization mass spectrometry, cyclic voltammetry, and colorimetric microculture assays. Stability studies demonstrated low stability of the complexes at pH 7.4 and 37 °C and a high reactivity toward proteins (binding rate constants in the ranges of 0.02-0.34 and 0.01-0.26 min-1 for albumin and transferrin, respectively). The redox potentials (between 0.25 and 0.35 V) were found to be biologically accessible for activation of the complexes in the tumor, and the indazole-containing compound shows the highest antiproliferative activity in vitro. © 2007 American Chemical Society
Safety and security
No full textThis paper is the sixth in a series of 8 that make up the evidence base for SDC report 'The role of nuclear power in a low carbon economy'.The document covers accident risk in plants (including a historical review of accidents), threats from design faults and terrorism, the implications of nuclear proliferation, and health impacts.Publisher PD
Combination of electrophoresis, chromatography, and magnetism in a single separation technique: Part 1: a first theoretical evaluation
No full textThe issue of evaporation loss of oil products and possible solutions
No full text© Research India Publications. The paper considers the issue of evaporation loss of oil products during storage, acceptance and delivery at bulk plants, fuel filling stations and oil refineries. The topicality of this issue is determined by the fact that it features both economic and environmental aspect. For example, fuel filling stations of Russia lose as the result of emission of light fractions of oil products up to 6 billion rubles per a year. Oil vapors worsen the ecological situation in large metropolises as most of fuel filling stations are located within the cities. In the real conditions hydrocarbon concentration is determined by the temperature of petroleum filled, degree and rate of reservoir filling as well as by concentration of these hydrocarbons in petroleum. The paper analyzes in details the causes and structure of hydrocarbon losses within oil products supply facilities. Comparative characteristic of the existing methods of tank vapor recovery and assessment of their efficiency are provided. Two new devices for vapor recovery during storage were proposed. It is shown that these devices allow ensuring efficient tank vapor recovery as well as improving efficiency of environmental protection at modern fuel filling complexes and bulk plants. At that gasoline quality is preserved as the result of return of light oil product fractions back to the reservoir
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