779 research outputs found
Evaluación del desempeño del personal para determinar el nivel de competencia en la “Empresa Metal Mecánica L&S Nassi” de la ciudad de Trujillo - 2013
No full textLa presente investigación “EVALUACIÓN DEL DESEMPEÑO DEL PERSONAL PARA DETERMINAR EL NIVEL DE COMPETENCIA EN LA EMPRESA METAL MECÁNICA L&S NASSI, DE LA CIUDAD DE TRUJILLO - 2013”, permite conocer el nivel de competencias de los trabajadores del área de producción de la empresa L&S NASSI. Han participado de la presente investigación 11 colaboradores del área de producción de la empresa metal mecánica L&S NASSI, a quienes se les aplicó el formato de evaluación del desempeño desarrollado por la Dra. Martha Alles (2011), adaptado a la realidad de la empresa por los investigadores estableciendo los siguientes indicadores de competencias en dos dimensiones: Credibilidad Técnica, Productividad, Iniciativa- Autonomía y Tolerancia a la Presión (Dimensión: Calidad Profesional) y Colaboración responsabilidad, Trabajo en Equipo y Aprendizaje Continuo (Dimensión: Actitud frente al trabajo). Los resultados de la investigación nos han permitido determinar que, según la prueba estadística t-student, el nivel de competencia alcanzado por los colaboradores del área de producción no es el esperado, existiendo una brecha o GAP entre el nivel de competencia alcanzado por el colaborador y el nivel de competencia exigido por la empresa.This research “PERFORMANCE ASSESSMENT TO DETERMINATE THE
LEVEL OF COMPETENCY OF THE WORKERS IN THE L&S NASSI METAL
MECHANIC COMPANY, TRUJILLO CITY – 2013”, is made to determinate the
level of competency of the workers, in the production area of the company.
For that purpose, eleven workers of the production area participated; they were
evaluated by the format of Performance Assessment developed by Dra. Martha
Alles (2011), adapted to the reality of the company by the researches, setting the
following indicators of competency in two dimensions: technical credibility,
productivity, Initiative- Autonomy and Tolerance to the Pressure (Dimension:
Professional Quality) and Collaboration, responsibility, Team Work and
Continuing Learning (Dimension: Attitude towards work).
The results of the investigation, allowed us, according to the t-student statistic
formula, determinate that, the level of competency achieved by the workers of the
production area, are not the required, where there is a gap between the level of
competency of the workers and the level of competency required by the
organization.Tesi
Diagnóstico organizacional de la función de producción para realizar un plan de mejora en la productividad y seguridad industrial de la Planta Industrial en la Empresa L&S Nassi SAC
No full textLa presente investigación tiene como propósito realizar un diagnóstico y evaluación organizacional de la función de producción en la planta industrial de la empresa L&S NASSI SAC, así como, elaborar un plan de mejora para optimizar la productividad y seguridad industrial.
La metodología aplicada ha permitido conocer la situación real de la empresa, descubrir problemas y áreas de oportunidad para fortalecer su función de producción.
Para el logro eficaz del diagnóstico, se realizaron reuniones con la alta dirección de la empresa mostrando su conformidad e intención de cambio para aplicar las sugerencias del plan de mejora.
En este proceso, se generó información a través de entrevistas y cuestionarios, luego se procedió a almacenar los datos y el ordenamiento de la información para su posterior análisis e interpretación para responder a las cuestiones planteadas en nuestra investigación.The present investigation has as intention realize a diagnosis and
evaluation organizational of the function of production in the industrial
plant of the company L&S NASSI SAC, as well as, elaborate a plan of
improvement to optimize the productivity and industrial safety.
The applied methodology has allowed to know the royal situation of the
company, to discover problems and areas of opportunity to strengthen
his function of production.
For the effective achievement of the diagnosis, meetings were realized
by the high direction of the company showing his conformity and
intention of change to apply the suggestions of the plan of improvement.
In this process, information was generated across interviews and
questionnaires, then one proceeded to store the information and the
classification of the information for his later analysis and interpretation to
answer to the questions raised in our investigation.Tesi
N-S chart honours project report : a Nassi-Scneiderman cartographer
No full textThis project involved the development of N-S Chart; a NassiShneiderman
Cartographer for the Apple Macintosh. N-S Chart is a tool
for drawing and maintaining Nassi-Shneiderman diagrams, and
incorporates the beneficial features of diagramming methods, and
automated computer graphics tools discussed in chapters 2 and 3. The
features of N-S Chart are discussed in chapter 7. Nassi-Shneiderman
charts (N-8 Charts), an alternative to the flowchart, are described in
chapter 5. A cartographer is someone who works with charts.
In the process of implementing the original Nassi-Shneiderman
diagramming technique, modifications and improvements to the method
were developed and implemented.
Flowcharts were designed in the days of 2nd generation languages.
They do not support the constructs used in todays 3GLs and 4GLs. NassiShneiderman
charts do.
However the original Nassi-Shneiderman diagrams did have a few
drawbacks which prevented them from becoming more widely used than
they have been. The problems of data specification and drawability have
been addressed in this project and successful solutions have been found.
Chapter 8 describes aspects of user interface design. Symbols have been
added to the drawing technique to support the specification of data inputs
and outputs. Symbols have been modified to clarify charts and the
drawing and maintenance process has been automated and simplified to
an almost trivial level. Details of the implementation of N-S Chart are
discussed in chapter 9 and possibilities for further extension are
mentioned in chapter 10
N-S chart honours project report : a Nassi-Scneiderman cartographer
No full textThis project involved the development of N-S Chart; a NassiShneiderman
Cartographer for the Apple Macintosh. N-S Chart is a tool
for drawing and maintaining Nassi-Shneiderman diagrams, and
incorporates the beneficial features of diagramming methods, and
automated computer graphics tools discussed in chapters 2 and 3. The
features of N-S Chart are discussed in chapter 7. Nassi-Shneiderman
charts (N-8 Charts), an alternative to the flowchart, are described in
chapter 5. A cartographer is someone who works with charts.
In the process of implementing the original Nassi-Shneiderman
diagramming technique, modifications and improvements to the method
were developed and implemented.
Flowcharts were designed in the days of 2nd generation languages.
They do not support the constructs used in todays 3GLs and 4GLs. NassiShneiderman
charts do.
However the original Nassi-Shneiderman diagrams did have a few
drawbacks which prevented them from becoming more widely used than
they have been. The problems of data specification and drawability have
been addressed in this project and successful solutions have been found.
Chapter 8 describes aspects of user interface design. Symbols have been
added to the drawing technique to support the specification of data inputs
and outputs. Symbols have been modified to clarify charts and the
drawing and maintenance process has been automated and simplified to
an almost trivial level. Details of the implementation of N-S Chart are
discussed in chapter 9 and possibilities for further extension are
mentioned in chapter 10
Evidences of competitive adsorption of hydrocarbons into an hydrophobic ZSM-5
No full textVolatile organic compounds and hydrocarbons constitute a significant fraction of the hazardous air and water pollution. Research on hydrocarbon removal has been mainly focussed on single components from air matrix, whereas the studies involving aqueous dilute solutions are few. However, in most environmental applications, these pollutants are present in the form of mixtures in very dilute aqueous solution. In this study, we report on evidence of 1,2-dichloroethane (DCE), methyl tert-butyl-ether (MTBE) and toluene (TOL) adsorption into ZSM-5 zeolite.
A combined diffractometric and gas chromatographic study was used to: 1) investigate the adsorptive properties of ZSM-5; 2) characterise its structure after the adsorption of selected contaminants; 3) localise the organic species in the zeolite pores; 4) compare the adsorption data for a mixture of these contaminants with concentrations in the ppb and ppm range.
The ZSM-5 sample is a commercial adsorbents, (SiO2/Al2O3 =280), purchased by Zeolyst International. Kinetics and adsorption isotherm batch data were obtained via Headspace Solid Phase Microextraction -Gas Chromatography. XRD powder patterns were collected on ZSM-5 before and after adsorption on a Bruker D8 Advance diffractometer. Thermal analyses (TG and DTA) were performed in air up to 900°C at 10°C/min. The experimental results prove that the kinetic of adsorption of all components is fast and indicates that competition exists between the organic compounds at low cosolute concentrations.
Rietveld refinements indicate that the relevant incorporation of DCE, MTBE and TOL in the ZSM-5 causes significant increase of all unit cell parameters in comparison to those of the untreated material as well as strong distortions of the channel systems where the contaminants are hosted. The very favorable adsorption kinetics along with the effective and highly irreversible adsorption of DCE, MTBE and TOL molecules into zeolite ZSM-5 pores make this cheap and environmental friendly material a tool with interesting applications for the removal of hydrocarbons from wastewater
Effect of antitumor platinum compounds with trans geometry on the induction of cytotoxicity and cell cycle modifications
No full textSINTESI E VALUTAZIONE BIOLOGICA DI NUOVI AGENTI POTENZIALMENTE UTILI NELLA TERAPIA DEL MELANOMA MALIGNO
No full textMalignant melanoma is an extremely aggressive tumour, which originates from the neoplastic transformation of melanocytes. The therapy of metastatic melanoma, whose incidence is dramatically increasing, continues to be a challenge since, regardless of the treatment approach used (chemotherapy, immunotherapy or immuno-chemotherapy), a long-term survival is quite uncommon.
In an attempt to improve the effectiveness of the anticancer drugs currently available and to decrease their systemic toxicity, in addition to exploit some biochemical characteristics rather specific of the melanoma cells, a useful approach might be also the use of prodrugs, targeted to the tumor cells, that would release the active drug directly into the tumor mass and/or their surrounding extracellular environment.
Aim of my Ph.D. work was the synthesis and the biological evaluation of three types of new compounds, designed as possible agents useful in an anti-melanoma therapy.
The first compound, which we synthesized and tested, was a peptide-paclitaxel conjugate containing three functional domains: a “targeting domain”, an “activation sequence” and the cytotoxic agent paclitaxel. The “targeting domain”, whose function was to direct the conjugate to the tumour mass, was represented by a cyclic peptide containing the RGD sequence that can bind selectively the αVβ3 integrin, a surface molecule overexpressed by both metastatic human melanoma cells and endothelial cells of tumour vessels. The “activation sequence”, which should allow a selective release of paclitaxel within the tumour mass, was represented by a short peptide, substrate of cathepsin B (a lysosomal and pericellular protease highly up-regulated in malignant tumours, including human melanomas). The third functional domain consisted of the anticancer drug paclitaxel.
The second type of prodrug, which we designed and tested, was a 4-mercaptophenol derivative, containing a butenone moiety, the 4-[(4-hydroxyphenyl)sulfanyl]-3-buten-2-one, obtained in its E and Z geometric isomers. This compound has been designed considering that: a) the 4-mercaptophenol moiety would be a good substrate for tyrosinase, an enzyme expressed at high levels in melanoma cells, where it is involved in the biosynthesis of melanin, and able to oxidize a variety of natural and synthetic phenols, giving rise to alkylating and cytotoxic o-quinones; b) an α,β unsaturated side chain, reactive towards GSH (present in relatively high concentrations in melanoma cells) would decrease cellular antioxidant defense against the oxygen free radicals (ROS) generated as by-products during melanin synthesis, in normal as well in tumor cells. Therefore, our prodrug should act as a bifunctional agent, capable of generating cytotoxic o-quinone species (following its oxidation by tyrosinase) and reducing GSH levels.
A third part of the present work has focused on the study of the naftoquinone alkannin and its two acetylated derivatives (1’-acetyl alkannin and 5,8,1’-triacetyl alkannin), as potential inhibitors of the human glutathione-S-transferase (GST) P1-1. This enzyme, which catalyzes the conjugation of GSH to a wide range of nucleophilic compounds, is expressed at high levels in many tumor cells, including melanoma cells, and is considered one of the factors responsible of tumor resistance towards anti-cancer agents. Therefore, a specific inhibitor of this enzyme could be useful in cancer therapy, making the tumor cells more sensitive to chemotherapeutic agents.Il melanoma maligno è un tumore molto aggressivo, la cui incidenza è in costante aumento, che origina dalla trasformazione di cellule chiamate melanociti. La terapia del melanoma metastatico continua ad essere una difficile sfida, in quanto, indipendentemente dall’approccio terapeutico utilizzato (chemioterapia, immunoterapia o immuno-chemioterapia), i soggetti affetti raramente presentano una sopravvivenza a lungo termine. Per migliorare l'efficacia dei farmaci antitumorali attualmente disponibili e per diminuirne la tossicità sistemica, oltre a sfruttare alcune caratteristiche biochimiche relativamente specifiche delle cellule tumorali, e del melanoma in particolare, un approccio utile potrebbe anche essere quello di indirizzare verso le cellule tumorali dei profarmaci, che rilascino il farmaco attivo direttamente all’interno della massa tumorale e/o nel loro intorno extracellulare.
I risultati riportati in questa tesi si riferiscono alla sintesi e alla valutazione biologica di tre nuovi tipi di composti progettati in questa ottica verso le cellule di melanoma.
Il primo composto studiato è stato un coniugato peptidico del paclitaxel contenente tre domini funzionali: un dominio di "indirizzamento", una sequenza di "attivazione" e il paclitaxel, appunto, quale agente citotossico. Il dominio di “indirizzamento", la cui funzione era quella di dirigere il coniugato verso la massa tumorale, era rappresentato da un peptide ciclico contenente la sequenza RGD, in grado di legarsi selettivamente e con alta affinità all’integrina αVβ3, una molecola di superficie sovra-espressa sia dalle cellule di melanoma che dalle cellule endoteliali dei nuovi vasi tumorali. La sequenza di “attivazione ", che avrebbe dovuto consentire un rilascio selettivo del paclitaxel all’interno della massa tumorale, era rappresentata da una sequenza peptidica substrato della catepsina B, una proteasi a localizzazione lisosomiale e associata a membrana, altamente sovraespressa in molti tumori, compreso il melanoma. Il terzo dominio funzionale era costituito dal farmaco antitumorale vero e proprio, cioè dal paclitaxel, il cui legame con il peptide - nelle aspettative - avrebbe dovuto causarne la momentanea inattivazione fino al momento della sua effettiva liberazione in sede tumorale.
Il secondo profarmaco testato è stato un derivato del 4-mercaptofenolo contenente una catena laterale butenonica, il 4-[(4-idrossifenil)sulfanil]-3-buten-2-one, ottenuto nei suoi due isomeri geometrici E e Z. Questo composto è stato progettato considerando che: a) la parte derivata dal 4-mercaptofenolo avrebbe dovuto essere un buon substrato per l’enzima tirosinasi (TYRase), un enzima espresso ad alti livelli nelle cellule di melanoma, perchè coinvolto nel processo di biosintesi della melanina, e in grado di ossidare una varietà di fenoli naturali e di sintesi, dando luogo a forme alchilanti e citotossiche come gli o-chinoni; b) la catena laterale butenonica (α,β insatura), essendo dotata di elevata reattività nei confronti del GSH, presente in concentrazioni relativamente elevate nelle cellule di melanoma, avrebbe dovuto sottrarre GSH alla cellula stessa, indebolendone di fatto le difese antiossidanti nei confronti dei radicali liberi dell’ossigeno (ROS) che si generano, come sottoprodotti, durante la sintesi di melanina sia in cellule normali che tumorali. Nelle aspettative, il profarmaco così progettato si sarebbe dovuto comportare come un agente bifunzionale in grado di formare o-chinoni citotossici in seguito alla sua ossidazione da parte della tirosinasi e in grado di ridurre al tempo stesso i livelli di GSH.
Infine, un terzo approccio ha riguardato lo studio dell’alcannina (colorante naturale a struttura naftochinonica) e di due suoi derivati acetilati, quali possibili inibitori dell’enzima umano glutatione-S-transferasi (GST) di tipo P1-1, enzima espresso ad alti livelli in molti tumori tra cui appunto il melanoma. GSTP1-1 è un enzima coinvolto nel metabolismo di fase II degli xenobiotici, in quanto catalizza la coniugazione del GSH ad una vasta gamma di composti nucleofili, ma esso è anche ritenuto uno dei fattori promuoventi la farmaco-resistenza del tumore. Un inibitore specifico di questo enzima potrebbe essere quindi estremamente utile in una terapia antitumorale, rendendo le cellule tumorali più sensibili agli agenti chemioterapici
Reactive transport of pollutants in porous media
No full textAccidental or deliberate crude oil spills have been, and still continue to be, a significant source of environmental pollution, and pose a serious environmental problem, due to the possibility of air, water and soil contamination. Chlorinated volatile organic compounds (VOCs), such as 1,1-dichloroethylene (DCE) and aromatic hydrocarbons, BTEX (benzene, toluene, ethyl benzene and xylene) constitute a significant fraction of hazardous air and water pollution. Human beings are exposed to elevated levels of a wide spectrum of VOCs, many of which have been found to be toxic and potentially carcinogenic. Removal of these organic contaminants from water and wastewater has been achieved using several treatment technologies, such as advanced oxidation processes, air stripping, reverse osmosis, ultrafiltration and adsorption.
Adsorption processes can be successfully used when contaminants are not amenable to fast biological degradation. Permeable Reactive Barriers (PRB) are one of the most promising passive treatment technologies, due to their effectiveness regarding various contaminants, and their low cost compared to other in situ technologies. Typical PRB configuration consists in a permeable treatment zone placed vertically to the flow path of groundwater, which contains reactive material that immobilises or decomposes the contaminants by adsorption as the groundwater flows through it.
PRBs are installed as permanent, semi-permanent, or replaceable units. A wide variety of pollutants are degraded, precipitated, sorbed or exchanged in the reactive zone, including chlorinated solvents, heavy metals, radionuclides and other organic and inorganic species.
Conventional permeable reactive barriers for the decontamination of water are based on systems which most widely use Granular Activated Carbon (GAC).
GAC has been shown to be only slightly effective in treating water containing very soluble compounds, such as oxygenated organics, or low molecular weight compounds, such as DCE and vinyl chloride (VC). However, their use for the removal of organic contaminants in water and wastewater applications can be complicated by the presence of dissolved natural organic matter in the water stream being treated, which can decrease the removal efficiency of GAC. When activated carbon is saturated, it has to be regenerated or renewed, which is rather an expensive operation. The adsorbed molecules are then released and still have to be destroyed by thermal treatments. Moreover, this additional treatment also degrades the activated carbon adsorption properties in the long term [1]. Zero-valent iron (ZVI), which directly degrades several contaminants, appears to be ineffective too, both on irreducible compounds such as DCE and chlorobenzenes as well as on hydrocarbons. Furthermore, when ZVI is used, it causes a reduction in the permeability of the barrier due to encrustations or precipitation of minerals which derive from the reactions between the ions of the oxidised metal and the substances contained in the groundwater [1-2]. Therefore, when operating with a barrier based on metallic iron alone, the chemical reduction reaction of the reducible compounds can require from 1 to 2 days. In this case, it is only the thickness of the iron which can ensure the time necessary for completing the reactions and large quantities are required to guarantee the complete decontamination of the groundwater.
Recently, high-silica zeolites were shown to be more effective than activated carbon or ZVI in removing certain organics from water [3-4].
The selection of zeolites from among the large variety of adsorbent materials is based on their stability and efficiency properties.
To date, the adsorption mechanisms of zeolites in gas phase systems have been widely investigated. On the contrary, studies and applications on organic pollutants adsorption in microporous zeolitic materials from aqueous media have been relatively scarce. Adsorption from gas phase systems can significantly differ from that observed from the corresponding aqueous solutions, due to the highly polar nature of water molecules. In literature, it has been reported that water plays a very important role in the diffusion of hydrocarbons in the zeolite pore system. In particular, large amounts of co-adsorbed water molecules block the migration of host molecules such as alkanes and olefins, thus reducing the adsorption capacity of zeolites, especially at low adsorbate concentrations. As a consequence, water acts as a screen between the cationic sites of the zeolite and the hydrocarbon molecules (screening effect) and reduces both the sorption volume (steric effect) and the aperture of the zeolite windows (blocking effect). On the contrary, small amounts of co-adsorbed water lower the extent of specific adsorption without significant blocking effects. However, as mentioned above, this research on hydrocarbon adsorption has also mainly been focused on single components from air matrices, whereas there are few studies involving aqueous dilute solutions. Nonetheless, in most environmental applications, these pollutants are present as very dilute aqueous solution mixtures.
The work developed in the present thesis is part of a wider project whose purpose is to study the interaction and mobility of groundwater pollutants adsorbed in zeolite pores, in order to improve the efficiency of permeable reactive barriers. This project involves Ferrara and Bologna Universities with the financial support of the ENI and the scientific support of Dr. Roberto Bagatin of the research centre of Novara. Several techniques were employed such as X ray diffraction, gas chromatography, IR spectroscopy, thermal analyses, as well as computational studies.
In this thesis, combined diffractometric, thermogravimetric and gas chromatographic techniques were employed to study the adsorption process in order to: 1) investigate the adsorptive properties of these hydrophobic synthetic zeolites; 2) characterise their structure after the adsorption of selected contaminants (1-2 dichloroethane, tert-butyl methyl ether and toluene); 3) localise the organic species in the zeolite channel system; 4) probe the interactions between organic molecules and framework oxygen atoms; 5) compare the adsorption data for a mixture of these contaminants with concentrations in the ppb and ppm range; 6) characterise the kinetic of the adsorption processes.
In particular, the thermodynamic and kinetic of the adsorption processes of contaminants on hydrophobic zeolites were obtained by using complementary, batch, linear and non-linear chromatography and thermogravimetry techniques. Batch and non-linear chromatography were mainly used to measure the adsorption isotherms for the compounds of interest. The adsorption isotherm is useful in representing the capacity of a zeolite to adsorb organics from waste, and in providing description of the functional dependence of capacity on the concentration of pollutants. Experimental determination of the isotherm allows to evaluate the feasibility of adsorption for treatment, to select a zeolite, and to estimate adsorbent dosage requirements. Moreover, it is possible to evaluate the adsorption energy distribution of the process from isotherm parameters. Batch and linear chromatography, instead, were employed to investigate the kinetic of the adsorption. Kinetics deals with changes in chemical properties in time and is especially concerned with the rate of changes and plays a fundamental role in determining the proper time contact for the removal of pollutant components from wastewater. In addition, an original theoretical model able to give information regarding the kinetic and the thermodynamic constants of systems in which both reactions and adsorption processes occur simultaneously was developed. To investigate the adsorption mechanism, diffraction techniques were employed to localize the organics adsorbed into the zeolite structure. The information gathered by this latter investigation – in cooperation with the Earth Science Department UNIFE - allows to define the interactions between organic molecules and zeolite framework. Finally, adsorption on mesoporous materials was investigated. It is well known that water is contaminated by different classes of substances, and zeolites are mainly suitable for molecules with dimensions comparable to that of their pores. However, many compounds belonging to the class of emergent contaminants have large molecular dimensions, and in such cases mesoporous materials can be more efficient than zeolites. To accomplish this task MCM-41 and HMS were synthesized and characterised – this work was carried out at the ‘Institut Charles Gerhardt (ICG), Matériaux Avancés pour la Catalyse et la Santé (MACS)’ at Montpellier (France) with the supervision of Prof. Francesco di Renzo and Dr. Anne Galarneau – and then the adsorption of acid perfluorooctanoic onto these mesoporous materials was performed
VHDL Codegenerierung aus Nassi-Shneiderman-Diagrammen
No full textEs wird eine bisher nicht beachtete
Modellierungsmethode für die VHDL Codegenerierung untersucht. Im
Gegensatz zu den häufig verwendeten Methoden, das Systemverhalten
über mathematische Funktionen, Zustandsautomaten oder
Blockschaltbilder zu beschreiben, werden Struktogramme verwendet. Es
wird ein System von Ersetzungsregeln erstellt, welches ein Nassi-
Shneiderman-Diagramm in einen verwendbaren Mehrzyklus-Datenpfad
umwandelt. Um das entwickelte Konzept in der Praxis zu erproben, wird
die Implementierungssprache Java verwendet, um sowohl einen
grafischen Editor als auch einen Codegenerator zu erstellen. Die Priorität
bei der Entwicklung des Editors liegt dabei auf einer einfachen
Benutzbarkeit und der Fähigkeit, simultan über das Netzwerk an einem
Diagramm arbeiten zu können. Dies wird durch die Verwendung von Java
Swing und RMI erreicht. Die auftretenden Besonderheiten und Probleme
des verteilten Systementwurfs werden analysiert und durch den Einsatz
von Entwurfsmustern gelöst. Die Fähigkeit zur VHDL Codegenerierung
wird durch zahlreiche Testfälle verifiziert und an verschiedenen
Anwendungsfällen theoretisch als auch praktisch untersucht.This thesis is about VHDL code generation. In contrary to the
common modeling types, like mathematical functions, state machines
and block diagrams, it will use Nassi-Shneiderman-Diagramms.
A graphical editor is implemented via JAVA RMI to ensure network
capability. The main feature is the ability to work on the shared diagrams
simultaneously.
The theoretical part includes the analysis of the system architecture as a
distributed system. The capability of generating code is revised via
theoretical and practical analysis of the generator output. This output will
be verified via several tests and examples
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