245 research outputs found
Agenesis of the oculomotor and trochlear nerves in a hydrocephalic foal.
No full textA case of internal hydrocephalus in a foal delivered by cesarean section is described. Thinning of the cortex, upset of the diencephaln and reduction of size of the mesencephalon were observed along with a peculiar distribution of the third and fourth cranials nerves[...
Effect of electric current stimulation in combination with external fixator on bone healing in a sheep fracture model | Effetto della stimolazione elettrica associata a fissatore esterno nella guarigione ossea in un modello di frattura nella pecora
No full textBiophysical stimulations with electric and electromagnetic fields have been demonstrated to accelerate the bone-healing rate. This study has been designed to investigate the effects of electricity directly connected with the central pins of an external fixator in an experimental osteotomy model in sheep. Thirty mg/kg of tetracycline chloride were administered on the 30th and on the 45th day after surgery for histomorphometric studies. Plain radiographs were obtained in standard projections every 15 days after surgery and were analyzed with a software program (Corel Photo-Paint Pro X2, Corel Corporation, Ottawa, Canada). The specimens obtained after 60 days were examined with histological analysis. The results show that biophysical treatment with alternating electricity in combination with external fixator enhances new-bone formation. The translational value of this study, due to the similarities between ovine and human species, suggests that this treatment could be useful in speeding the bone-healing rate both in animals and humans
Muttini-Conti G. — La popolazione del Piemonte nel secolo XIX
No full textC A. Muttini-Conti G. — La popolazione del Piemonte nel secolo XIX. In: Population, 21ᵉ année, n°1, 1966. pp. 159-160
Un bibliotecario genovese: Pietro Muttini
No full textPartendo dall’analisi delle fonti d’archivio e della produzione editoriale, l’articolo ricostruisce l’attività, gli studi e gli interessi di Pietro Muttini (1881-1947), che a lungo collaborò con la Società Ligure di Storia Patria e che nel contempo salì tutti i gradini della carriera di bibliotecario alla Biblioteca Berio: assunto come “distributore” nel 1910 ne sarebbe divenuto direttore per un breve periodo nel biennio 1945-1946.
Beginning from the analysis of archival sources and his publishing production, this article reconstructs the work, studies and interests of Pietro Muttini (1881-1947), who had a long collaboration with the Società Ligure di Storia Patria (Ligurian Society of History) and climbed up the ladder of responsibility as librarian at the Berio Library: hired as a “distributor” in 1910 he became its director for a short period between 1945-1946
Risposta clinica alla somministrazione intraarticolare di ialuronato di sodio nel trattamento di artropatie asettiche del cavallo sportivo.
No full textModificazioni indotte nel liquido sinoviale di giunture del cavallo dalla somministrazione intraarticolare di jaluronato di sodio.
No full textMuttini-Conti G. — La popolazione del Piemonte nel secolo XIX
No full textC A. Muttini-Conti G. — La popolazione del Piemonte nel secolo XIX. In: Population, 21ᵉ année, n°1, 1966. pp. 159-160
Applications of Placenta-Derived Cells in Veterinary Medicine
No full textThe field of regenerative medicine is moving toward clinical practice. In this context, domestic animals cover a dual role, acting as both patients and valuable translational models.
The absence of regulatory and ethical guidance has encouraged rapid translation of unproven stem cell protocols in veterinary medicine. However, evidenced-based preclinical and clinical trials of stem cell therapies performed in domestic animal models are critical in advancing stem cell therapies. To this end, placenta-derived stem cells have been recently investigated in domestic animals, and a large amount of information has been obtained in regard to cell origin, isolation, enrichment, and processing. Aside from their high in vitro plasticity, four main characteristics of placenta-derived cells make them attractive candidates for therapeutic approaches: stemness features common to cells from large-sized mammals, low immunogenicity and immunomodulatory properties, multilineage regenerative capacity, and the successful engraftment and long-term survival in various host tissues after auto- or allo/xenotransplantation.
Preclinical studies performed on experimental models, as well as clinical trials designed to treat spontaneous diseases, have demonstrated beneficial regenerative effects, particularly those exerted by amniotic-derived cells. These effects arise from a mutual tissue-specific cell differentiation (tendon- and bone-derived lineage cells), and paracrine secretion of bioactive molecules in host tissues that ultimately drive crucial repairing processes (e.g., anti-inflammatory, antifibrotic, angiogenic, and neurogenic).
The knowledge acquired thus far on the mechanisms of action of placental-derived stem cells and on their effectiveness and safety in animal models highlights promising perspectives for the treatment of musculoskeletal disorders and widespread common and incurable pathologies affecting companion animals and humans
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