260 research outputs found
The Italian contribution to studies on the biological rhythms implicated in psychiatric disorders
No full textThis editorial summarizes the main studies, carried out in the last 10 years, by various Italian research groups, on the alterations of circadian rhythms in psychiatric disorders. The results of these researches, as well as those obtained in various international contexts, encourage to teach in the medical schools for psychiatry, about the new chronoterapeutic interventions and the implementation of combined therapies for increasingly personalized psychiatric therapies
CoViD-19 and stress in the pandemic: "sanity is not statistical"
No full textCoViD-19 pandemic is causing serious consequences on mental health, consequences that are considered that bad that World Health Organization has affirmed that mental health defence is priority in this particular moment of development of pandemic. In light of this alertness, what we are interested in approaching in this work, is the specific stress condition caused by pandemic, which underlies and precedes the described classification of diseases and which is going towards an increase in the entire world, including . The stress caused by pandemic is a new condition in comparison with what is known in clinical practice and with what is included in the classification of mental disorder. The ongoing stress condition and the mixture of different types of unconventional stress, which not only hits the present but also disrupts the future, create an entirely new form of clinical condition given by pandemic
Studio naturalistico sull’impiego degli antipsicotici nella formulazione long-acting negli SPDC di Roma e del Lazio
No full textIntroduction. Long-acting depot antipsychotic medication given by was developed in 1960s to simplify the medications process and conteract problems with treatment adherence. This report examines 1 day of long-acting antipsychotic therapy in admitted patients to SPDC of Rome city and Lazio. Materials and Method. A naturalistic study, multicenter trial was designed to evaluate the clinical features of patients treated with antypsychotic depot in a setting specialized in the care of patients suffering from serious long-term mental illness. Results. Of the 163 patients, 153 (94.9%) had psychotic disorder, 8 (4.9%) bipolar disorder, 1 personality disorder and 1 Obsessive-Compulsive Disorder (OCD). Patients treated with haloperidol depot were 136 (83.4%), 18 (11%) with fluphenazine depot, 5 (3.1%) with risperidone depot, 2 (1.2%) with zuclopentixol depot, 1 (0.6%) with penfluridol depot and 1 (0.6%) with perfenazine. Conclusions. The study suggests a target to depot therapy: a male patient with psychotic disorder, low compliance, low insight, instability of psychopatological status, positive symptomatology and with aggressive behaviour
Data and hypotheses on the role of nerve growth factor and other neurotrophins in psychiatric disorders
No full textNerve growth factor (NGF) was discovered and characterized for its role on the growth, differentiation and maintenance of specific neurons of the peripheral nervous system. Subsequent studies revealed that NGF is synthesized and released within the central nervous system and exerts a trophic and functional role on basal forebrain cholinergic neurons; it is involved in a protective role following brain insults induced by an epileptic status, seizure, as well as surgical and chemical lesions. More recently our collaborative studies provided evidence that NGF is implicated in neurobehavioral response including cerebral alterations associated with psychiatric disorders. In this brief review, ongoing and emerging data are presented and discussed. (C) 2000 Harcourt Publishers Ltd
Dati acquisiti ed ipotesi emergenti sul ruolo delle Neurotrofine, in particolare dell’NGF, in patologie di natura psichiatrica
No full textStudio naturalistico sull'impiego degli antipsicotici nella formulazione long acting negli SPDC di Roma e del Lazio
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