6,866 research outputs found
Market Value and Patent Citations: A First Look
No full textAs patent data become more available in machine-readable form, an increasing number of researchers have begun to use measures based on patents and their citations as indicators of technological output and information flow. This paper explores the economic meaning of these citation-based patent measures using the financial market valuation of the firms that own the patents. Using a new and comprehensive dataset containing over 4800 U. S. Manufacturing firms and their patenting activity for the past 30 years, we explore the contributions of R&D spending, patents, and citation-weighted patents to measures of Tobin's Q for the firms. We find that citation-weighted patent stocks are more highly correlated with market value than patent stocks themselves and that this fact is due mainly to the high valuation placed on firms that hold very highly cited patents.
Ne II Observations of Gas Motions in Compact and Ultracompact H II Regions
No full textWe present high spatial and spectral resolution observations of 16 Galactic compact and ultracompact H II regions in the [Ne II] 12.8 mu m fine-structure line. The small thermal width of the neon line and the high dynamic range of the maps provide an unprecedented view of the kinematics of compact and ultracompact H II regions. These observations solidify an emerging picture of the structure of ultracompact H II regions suggested in our earlier studies of G29.96-0.02 and Mon R2 IRS 1; systematic surface flows, rather than turbulence or bulk expansion, dominate the gas motions in the H II regions. The observations show that almost all of the sources have significant (5-20 km s(-1)) velocity gradients and that most of the sources are limb-brightened. In many cases, the velocity pattern implies tangential flow along a dense shell of ionized gas. None of the observed sources clearly fits into the categories of filled expanding spheres, expanding shells, filled blister flows, or cometary H II regions formed by rapidly moving stars. Instead, the kinematics and morphologies of most of the sources lead to a picture of H II regions confined to the edges of cavities created by stellar wind ram pressure and flowing along the cavity surfaces. In sources where the radio continuum and [Ne II] morphologies agree, the majority of the ionic emission is blueshifted relative to nearby molecular gas. This is consistent with sources lying on the near side of their natal clouds being less affected by extinction and with gas motions being predominantly outward, as is expected for pressure-driven flows.NSF AST-0607312, NSF-0708074SOFIA USRA8500-98-008NYSTAR Faculty Development ProgramNASA NNG 04-GG92G, CAN-NCC5-679Lunar and Planetary InstituteAstronom
Verification of the analytical characteristics of troponin assays in the laboratory : A how to guide
No full textIt is important that both laboratory staff performing troponin measurement and clinicians who interpret troponin results should 'know their routine laboratory's troponin assay' and its performance characteristics. International quality systems
established by the International Organization for Standardization (ISO) and accepted by clinical laboratories worldwide require the verification of a new method. As a minimum, a troponin method must be verified as showing 'fitness for purpose' before being used to produce analytical data for patient care.
The analytical performance characteristics of troponin assays that require an initial verification include imprecision and limit of quantitation. Validation of the upper reference limit that has been established by the manufacturer is also highly desirable, if possible. If the assay is replacing a previous assay, a method comparison and, if possible, an audit
of performance should also be done. Investigation of other characteristics such as limit of blank, limit of detection, interferences and linearity is optional and depends on a laboratory's situation and the availability of resources to do this
work. The monitoring of assay performance requires use of appropriate Intemal Quality Controls to assess the assay traceability (bias) and imprecision, and participation in an External Quality Assessinent Scheme to evaluate the assay accuracy and laboratory performance. In addition, the introduction of newer more sensitive troponin assays may require
clinical validation in collaboration with local cardiology units and emergency medicine departments, and auditing of the impact of implementation of these more analytically sensitive assays.
The following chapter provides a 'how to' guide to clinical laboratories for the verification and monitoring of the analytical performance of troponin assays
Introduction and overview of the classification of the lymphoid neoplasms.
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What Have I Done?
No full textA transcribed three page interview of WSU Mathematics instructor, Dr. Arthur DuPre\u27, by Sanford H. Jaffe, that is critical of the management of education at WSU at the time.https://corescholar.libraries.wright.edu/alternative_newspapers/1065/thumbnail.jp
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma.
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