1,747 research outputs found

    La tombe de l'évêque A... et la sépulture ecclésiastique à Limoges

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    Dabrowska-Zawadzka Eźlbieta. La tombe de l'évêque A... et la sépulture ecclésiastique à Limoges. In: Bulletin de la Société Nationale des Antiquaires de France, 2000, 2004. pp. 248-264

    DMEK Surgery at a Tertiary Hospital in Sweden. Results and Complication Risks

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    Kinga Dabrowska-Kloda,1 Eydis Olafsdottir,1 Anastasia Stefanou,1 Sven Crafoord1,2 1Department of Ophthalmology, Örebro University Hospital, Örebro, Sweden; 2Department of Ophthalmology, Faculty of Medicine and Health, Örebro University, Örebro, SwedenCorrespondence: Kinga Dabrowska-Kloda, Department of Ophthalmology, Örebro University Hospital, PO Box 1613, Örebro, SE 70116, Sweden, Tel +46 19 6021000, Fax +46 19 6021052, Email [email protected]: This study reports clinical outcomes up to 6 years after Descemet’s membrane endothelial keratoplasty (DMEK) performed at the Department of Ophthalmology, Örebro University Hospital, Örebro, Sweden.Methods: The study has a cross-sectional and case series design. Inclusion criteria were all DMEK-operated eyes during 2013– 2018 until repeat keratoplasty.Results: Altogether 162 eyes from 120 patients were enrolled. Among eyes without preoperative comorbidities, examined 1– 6 years after DMEK, 85.8% achieved visual acuity of 0.1 logMAR or better. The median endothelial cell density (ECD) loss was 27% in a cohort of eyes examined 1– 2 years post-DMEK, 31% at 2– 3 years, 42% at 3– 4 years, and > 60% at 4– 6 years post–DMEK. ECD at the examination timepoint was correlated with donor ECD (as expected) and time since surgery.Conclusion: The results from DMEK surgeries in Örebro, Sweden, are promising. Further studies with even longer follow–up are needed to evaluate graft sustainability.Keywords: DMEK, Descemet’s membrane endothelial keratoplasty, endothelial cell density, endothelial cell loss, corneal surgery in Sweden, corneal surgery in Scandinavi

    The Place of Universal Grammar in the Study of Language and Mind: A Response to Dabrowska (2015)

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    Generative Linguistics proposes that the human ability to produce and comprehend language is fundamentally underwritten by a uniquely linguistic innate system called Universal Grammar (UG). In her recent paper What is Universal Grammar, and has anyone seen it? Ewa Dabrowska reviews a range of evidence and argues against the idea of UG from a Cognitive Linguistics perspective. In the current paper, I take each of Dabrowska’s arguments in turn and attempt to show why they are not well founded, either because of flaws in her argumentation or because of a careful consideration of the available empirical evidence. I also attempt to demonstrate how evidence from the fields Dabrowska reviews actually supports the notion of UG. However, arguments are additionally presented in favor of integrating an understanding of domain-specific UG with an understanding of domain-general cognitive capacities in order to understand the language faculty completely

    MARIA SZUMSKA DABROWSKA ABOUT POLISH SETTLERS IN BOSNIA 1935

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    Autorica tumači povijesni kontekst položaja poljskih naseljenika u Bosni i Hercegovini na temelju izvještaja koji je poljska književnica Maria Dabrowska izradila za poljsku vladu prigodom svog boravka u Bosni i Hercegovini 1935. U članku se analizira politički, društveni i kulturni položaj poljskih kolonista te okolnosti zbog kojih su se nakon Drugog svjetskog rata vratili u svoju matičnu državu.The article analyzes the conditions under which Polish newcomers settled in Bosnia-Herzegovina between 1890 and 1946. By encouraging foreign settlement, the government of Austria-Hungary wanted to enhance the economic conditions in Bosnia-Herzegovina after the annexation of that region. A portion of foreign settlers in Bosnia came from Poland. Most of the Poles inhabited the following districts: Prnjavor, Derventa, Banja Luka, Bosanska Gradiška, Bosanski Novi and Prijedor. During World War II a number of them temporarily settled in Slavonia. In 1946 there was an organized transfer through which the Polish settlers from Bosnia returned to their homeland Poland

    Psychological functioning of patients undergoing oral surgery procedures during the regime related with sars-cov-2 pandemic

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    The coronavirus pandemic has become a huge global challenge medically, economically and psychologically. The COVID-19 pandemic shows that the population can experience general psychological distress. The sanitary regime in dental offices and lack of vaccine for coronavirus may have an impact on the level of dental anxiety among patients undergoing oral surgery procedures. A clinical study was conducted between November 2019 and September 2020. A total of 175 patients (n = 175) were enrolled in the research. The aim of the study was to assess the attitude of patients towards the new situation related to the reduced availability of dental offices providing oral surgery procedures. The level of anxiety associated with surgical intervention was measured using a self-made COVID-19 questionnaire and the MDAS scale. The ED-5Q questionnaire and EQ-VAS scale were also used in this research. The study showed that 21.9% of respondents presented with increased anxiety about a dental visit compared with the time before the pandemic. This epidemiological situation has led to an overwhelming increase in moderate dental anxiety (M: 11.4) among patients undergoing oral surgery procedures. The quality of patients’ health (EQ-VAS) related to the impact of the coronavirus pandemic and the quarantine decreased by 10 percentage points. Oral surgeons should be prepared for more anxious patients in dental offices during the pandemic

    Essays on global safety governance : challenges and solutions

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    This book presents an interdisciplinary collection of essays providing analyses of global governance of safety and security in various policy fields, ranging from financial crises to cyber-security. The volume offers essential insights about both European and international measures, normative frameworks and regulatory interventions aimed at controlling risks, preventing hazards and managing disasters. The book can attract attention of both academics and practitioners interested in global risk regulation and politics, public policy, as well as in EU and transnational governance.-- Foreword, Brigid Laffan -- Introduction, Patrycja Dabrowska-Klosinska; -- Part I FINANCIAL AND ECONOMIC STABILITY: Safety, Risk, Governance and the Eurozone Crisis: Rethinking the Conceptual Merits of 'Global Safety Governance', Anna Visvizi -- Restructuring Global Governance of the Financial System: a Framework for Preventing Systemic Risk, Laura Ammannati -- Part II ENERGY AND CLIMATE: Transformations in the Regional Security Energy Complex in North America, Roberto Domínguez -- Security of Supply and Solidarity: Challenges for the EU’s Common Energy Policy, Bartlomiej Nowak -- The Changing Landscape of the Global Climate Policy. Can Global Negotiations Lead to a New Climate Agreement?, Joanna Mackowiak-Pandera -- The Council of Europe System: Environmental Protection and Climate Change, Hanna Machinska -- Part III CITIZEN PROTECTION AND DEFENCE: The EU’s Role in Crisis and Disaster Management within the Union: Post-Lisbon Developments, Agnieszka Nimark; --Union Citizenship and Safety Governance – Challenges in the Protection of Union Citizens by Diplomatic and Consular Authorities, Dagmara Jasinska -- The Reform of EU Visa Policy: at the Crossroads of Facilitation and Security, Filip Jasinski -- Governance of Safety and Security in Cyberspace, Patryk Pawlak -- Defense-Industrial Transformations and State Sovereignty, Marc R. DeVore -- Bibliograph

    Interdisciplinarity Dimension in Research Information Systems – Evidence from Poland

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    AbstractResearch information systems (RIS) or scientific information systems (SIS), alike enterprise information systems (EIS), should cover interdisciplinarity aspects as a dimension that influences significantly research potential and activity of particular scientists.The aim of the work is to investigate the Polish scientific environment related to life sciences and engineering, with reference to its interdisciplinarity. It is believed that researchers having knowledge and experience in many different scientific areas are more successful and prone to make substantial scientific discoveries. Analysing Polish scientific achievements with respect to research projects granted and publications of the leading researchers, author states that scientists with multi-scientific background are more effective in granting additional funding for research. However, multidisciplinarity (interdisciplinarity), in terms of subject areas of specialization, has limitations. Author expects, that number of disciplines in which particular scientist has an experience might be extended with a success only to certain level.Preliminary results suggest, that interdisciplinarity background of individual scientists need to be incorporated in RIS/SIS as an obligatory dimension. It is of great importance for potential research cooperation, policy advisors and authorities financing research activities, as well as for business searching for professionals in differentiated scientific fields

    Impact of ferromanganese ore pollution on phytoplankton CO2 fixation in the surface ocean

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    Because ferromanganese polymetallic crusts can become a global resource of valuable elements the ecological impact of seafloor crust mining requires evaluation. Whilst the detrimental impact on deep-ocean benthos is established, experimental evidence about the mining hazard to surface-ocean is sparse. When retrieved, mined crusts can leach elements potentially harmfull to the core oceanic CO2-fixers – phytoplankton. To directly assess the magnitude of this potential hazard at ocean-basin scale, we examine the impact of ore slurry on phytoplankton CO2 fixation along a meridional transect through the South Atlantic Ocean. Within 12 h crust slurry additions caused a 25% decrease of CO2 fixation in the subtropical region and 15% in the temperate-polar region. Such moderate susceptibility of phytoplankton indicates limited release of harmful elements from tested polymetallic powder. Although this implies that environmentally sustainable seafloor mining could be feasible, longer-term complex studies of the mining impact on the surface ocean are required

    Human bone marrow mesenchymal stem cell-derived extracellular vesicles attenuate neuroinflammation evoked by focal brain injury in rats

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    Background Ischemic stroke is the major cause of long-term severe disability and death in aged population. Cell death in the infarcted region of the brain induces immune reaction leading to further progression of tissue damage. Immunomodulatory function of mesenchymal stem cells (MSCs) has been shown in multiple preclinical studies; however, it has not been successfully translated to a routine clinical practice due to logistical, economical, regulatory, and intellectual property obstacles. It has been recently demonstrated that therapeutic effect of intravenously administered MSCs can be recapitulated by extracellular vesicles (EVs) derived from them. However, in contrast to MSCs, EVs were not capable to decrease stroke-induced neuroinflammation. Therefore, the aim of the study was to investigate if intra-arterial delivery of MSC-derived EVs will have stronger impact on focal brain injury-induced neuroinflammation, which mimics ischemic stroke, and how it compares to MSCs. Methods The studies were performed in adult male Wistar rats with focal brain injury induced by injection of 1 mu l of 50 nmol ouabain into the right hemisphere. Two days after brain insult, 5 x 10(5) human bone marrow MSCs (hBM-MSCs) labeled with Molday ION or 1.3 x 10(9) EVs stained with PKH26 were intra-arterially injected into the right hemisphere under real-time MRI guidance. At days 1, 3, and 7 post-transplantation, the rats were decapitated, the brains were removed, and the presence of donor cells or EVs was analyzed. The cellular immune response in host brain was evaluated immunohistochemically, and humoral factors were measured by multiplex immunoassay. Results hBM-MSCs and EVs transplanted intra-arterially were observed in the rat ipsilateral hemisphere, near the ischemic region. Immunohistochemical analysis of brain tissue showed that injection of hBM-MSCs or EVs leads to the decrease of cell activation by ischemic injury, i.e., astrocytes, microglia, and infiltrating leucocytes, including T cytotoxic cells. Furthermore, we observed significant decrease of pro-inflammatory cytokines and chemokines after hBM-MSC or EV infusion comparing with non-treated rats with focal brain injury. Conclusions Intra-arterially injected EVs attenuated neuroinflammation evoked by focal brain injury, which mimics ischemic stroke, and this effect was comparable to intra-arterial hBM-MSC transplantation. Thus, intra-arterial injection of EVs might be an attractive therapeutic approach, which obviates MSC-related obstacles
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