1,720,999 research outputs found
Valutazione quantitativa del dispendio energetico durante il cammino in bambini affetti da Paralisi Cerebrale Infantile
Multisite trial on efficacy of constraint-induced movement therapy in children with hemiplegia: study design and methodology.
OBJECTIVE: In the past decades, several treatment approaches have been used to improve upper limb function in hemiplegic cerebral palsy. Only recently has constraint-induced movement therapy emerged as a treatment approach for children with hemiplegic cerebral palsy with the aim of reversing the behavioral suppression of movement in the affected upper limb. To date, evidence on this treatment has been very poor and limited, because all currently available trials reveal methodological limitations and a need for additional research to support the application of this treatment technique. This article presents the methodological choices, design, and main characteristics of an ongoing controlled clinical trial on the effectiveness and safety of constraint-induced movement therapy combined with an intensive rehabilitation program and compared with two comparison groups: one treated with an intensive rehabilitation program and the other with standard treatment.
METHODS: Twenty-one rehabilitation sites are currently recruiting patients with hemiplegic cerebral palsy, aged between 2 and 8 yrs, who have never undergone constraint therapy. Primary outcome measures include two major domains: upper limb motor ability (Quality of Upper Extremity Skills Test) and hand function assessment evaluating both grip function and spontaneous use of the affected side (Besta scale). Secondary outcome measures concern overall function, behavior, compliance, and satisfaction with treatment program of both child and family. Patients' follow-up is of 12 mos after treatment.
RESULTS: Research in children has always been neglected in comparison with adults, because of ethical reasons regarding the use of children for experimental purposes. The consequence has been the utilization of treatment and assessment tools and techniques that have not always been tested in pediatric patients or evidence is very scarce.
CONCLUSION: Discussing and working on pediatric research methods represents an urgent need in rehabilitation research
Cognitive ability assessment by Brain–Computer Interface: Validation of a new assessment method for cognitive abilities
Constraint-Induced Movement Therapy vs Bimanual Intensive Training in Hemiplegic Cerebral Palsy: preliminary results
OBJECTIVE: In children with hemiplegic cerebral palsy (CP), impairment of upper extremity (UE) both in strenght and motor control represents an obstacle to exploration, self-care, activities of daily living, represents a main target of several treatment approaches. Constraint Induced Movement Therapy (CIMT) is a promising approach, but its efficacy is still object of a debate. Aim of this study is to measure the effect of CIMT on patients with hemiplegic CP after the end of 10-weeks intensive treatment practice.
DESIGN: Designed as a multi center, prospective, cluster-randomized controlled clinical trial. CIMT is compared with ah Intensive Rehabilitation Program (IRP) of bimanual training. Primary outcome measures concern UE motor ability (QUEST) and assessment of affected hand's function in spontaneous use (Besta Scale). Secondary outcome measures concern overall function, behavior, stress, compliance and satisfaction with treatment program of both child and family.
RESULTS: 105 patients were recruited (treatment groups CIMT (n=39), bimanual IRP (n=33) and Standard Treatment (n=33)). Statistically significant changes are observed in the global score before and after treatment of the 2 groups (CIMT and IRP group) of children assessed with the Besta Scales (CIMT p=0.002; IRP p<0.0001, and QUEST (CIMT p<0.0001; IRP p=0.0143). In CIMT group the higher improvement is observed in grasp function (p=0.0019). In IRP group, the improvement is more significant in activities of spontaneous use (p=0.0005) and ADL in the younger (p=0.0001). In IRP group, children show a significant improvement in the non affected hand, while CIMT patients show worse function for grasp.
CONCLUSIONS: Our results demonstrate that a substantial improvement of paretic hand function was observed in children treated both with constraint of the unaffected hand and intensive unilateral practice and those treated with intensive bilateral practice without restriction. CIMT results were particularly effective for grasp function, while IRP ameliorates ADL and spontaneous use
Research for a correlation between femoral anteversion and kinematic knee deviations in children with Cerebral Palsy
Comparison of gait strategy in children with hereditary spastic paraplegia to children with spastic diplegia using Gait Analysis
Comparison of gait strategy between autistic subjects and idipathic toe-walkers using gait analysis
Comparison of gait strategy in subjects with hereditary spastic paraplegia to subjects with spastic diplegia using gait analysis
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