2,613 research outputs found

    Visitare il Risorgimento: turismo patriottico e diplomazia della memoria a Solferino e San Martino (1859-1909)

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    In the 19th century, battlefields played an increasingly important role in the imaginaries and sensibilities of the public, establishing themselves as destinations of a new travel experience that can be defined as patriotic tourism. The article will consider the Italian Risorgimento, presenting the battle of Solferino and San Martino as a case study. More precisely, it will reconstruct the touristic and memorial policies implemented by the Society of Solferino and San Martino, from the aftermath of the battle until the celebration of its fiftieth anniversary in 1909, under the different presidencies of Luigi Torelli, Vincenzo Stefano Breda and Carlo Maluta. A transnational perspective will also be adopted, analysing touristic flows from abroad and the central role played by French diplomacy in publicising and promoting the sites of the 1859 Campaign

    Immersive Risorgimento: The Panoramas of the Battle of Solferino in France and Italy

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    The years between the end of the 18th century and the beginning of the 19th century were marked by a great media transformation that led to a process of spectacularisation of politics. The war dimension was decisively affected by this transformation. A whole set of new cultural products offered to the public a virtual participation in war events of the time. Panoramas were the most effective ones, as they allowed for an immersive experience of the battlefields. At the same time, panoramas conquered the interest of institutions which integrated them into their policies of spectacularisation. The aim of this paper is to show how panoramas were crucial in the 19th-century process of militarisation of the imageries, by presenting the Italian unification, the so-called Risorgimento, as a case study. More precisely, the paper will focus on the panoramas devoted to the battle of Solferino (June 24, 1859), in which the Piedmontese and French armies defeated the Austrians. The Panorama of the Battle of Solferino, painted by Jean-Charles Langlois in 1865, and the similarly themed ones exhibited in Milan in 1881 and in Turin in 1884, will be discussed

    Lo spettacolo della guerra. I «panorami» delle campagne rivoluzionarie e napoleoniche tra Inghilterra e Francia (1793-1816)

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    In 1787 Robert Barker, an Irish painter living in Edinburgh, patented the panorama, an immense circular painting which for the first time allowed viewers to immerse themselves in the canvas. Launched in London in 1791, the panorama rapidly spread throughout Europe, becoming particularly popular in Paris. The aim of this article is to reconstruct the genesis of the panorama industry in London and Paris between 1793 and 1816, a period in which war between France and England monopolized the market. More precisely, the article will investigate the reasons for the success of the military panorama, highlighting its decisive role in the transformation of public imaginary and the spectacularization of war

    Dentro la «boutique» filellenica. I «panorami» della Guerra d'indipendenza greca (1821-1832)

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    In 1821, the outbreak of the Greek War of Independence sparked a philhellenic mobilization that drew in the European public with a never-before-seen intensity. The media, and military panoramas in particular, played a decisive role in this veritable «Graecomania». Patented in 1787, the panorama consisted in an immense circular canvas, allowing the spectator to be completely immersed in the painted subject. Having faced a crisis with the end of the Napoleonic wars, the military panorama received fresh impetus from the Hellenic conflict, and it became a huge success, especially in Paris and London. Filling a gap in the scientific literature, this article aims to reconstruct the story of the philhellenic panoramas produced in France and England with a transnational perspective, highlighting the innovative ways through which they mediatized and spectacularized the Greek War of Independence. More precisely, the philhellenic season launched two formats: the fixed panorama, perfected in France by Jean-Charles Langlois, and the moving panorama, popularized in England by a varied crowd of stage designers and entertainment entrepreneurs

    The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine

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    D-(−)-Lentiginosine [(−)-4], the nonnatural enantiomer of the iminosugar indolizidine alkaloid L-(+)-lentiginosine, acts as apoptosis inducer on tumor cells of different origin, in contrast to its natural enantiomer. Although D-(−)-4 exhibited a proapoptotic activity towards tumor cells at level lower than the chemotherapeutic agent, SN38, it was less proapoptotic towards normal cells and less cytotoxic. Apoptosis induced by D-(−)-4 was caspase-dependent, as shown by the increased expression and activity of caspase- 3 and -8 in treated cells, and by inhibition following treatment with the pan caspase inhibitor, ZVAD-FMK. This study highlighted how a natural iminosugar alkaloid and its synthetic enantiomer, which were simply known for their inhibition against a fungal glucoamylase, could behave in a complete different way when tested towards cell growth and death of cells of different origin

    Aphyosemion grelli (Cyprinodontiformes: Nothobranchiidae), a new species from the Massif du Chaillu, southern Gabon

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    A new species of Aphyosemion is described from Gabon, based on ten specimens collected in a small stream belonging to the hydrographic system of the Ikoy River on the northwestern edge of the Massif du Chaillu. Aphyosemion grelli is distinguished from all congeners by possessing a unique colour pattern of the unpaired and pelvic fins in the female consisting of the combination of a yellow basal portion and greyish to dark grey broad margin. Males of the new species share the black margins of the unpaired fins with A. congicum, A. labarrei, A. ocellatum, A. passaroi, and A. teugelsi, but differ from these by the combination of colouration characters and morphology. Phylogenetic relationships of the new species are still unclear; a possible close relationship with the A. coeleste group is tentatively excluded because, although geographically close, there are differences on flank colour pattern, head length and number of anal-fin rays

    Umbilical cord blood: The role of apoptosis in the control of CD34+ cell counts

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    Background and Objective: Cord blood obtained at delivery can be used for hematopoietic precursor cells (HPC) transplantation. The major limit for its success is represented by the low cellular yield of the stem cell population. The objective of this study was to determine the role played by apoptosis in the numerical control of CD34+ cell counts. Design and Methods: Umbilical Cord blood samples were collected from 15 women at the time of the delivery and cord blood units processed. Cells, collected following 24 h and 48 h of incubation, were analysed by flow cytometry using the gating strategy. Results: Remarkable levels of apoptosis were detected in the stem cell population and a significant difference between apoptosis mean values at 24 h and 48 h within CD34+ cells were found. The difference between the percentage of apoptosis in CD34+ cells and that in the remaining population was significant both at 24 h and at 48 h. Conclusions: CD34+ cells have a higher likelihood to undergo apoptosis in comparison to the remaining ones present in umbilical cord blood. This process of cellular death plays a major role in the control of CD34+ cell counts in placental blood and influence, for this reason, the possibility of success of a cord blood transplantation. © 2002 Elsevier Science Ltd. All rights reserved

    Thymic hormones and cytokines

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    The discovery and the first studies on thymic hormones (TH) are historically linked with their role on the developmental events of T lymphocytes that occur within the thymus. However, paradoxically, during the most recent years, much more information about the effects of TH on mature effector cells' in relation with those indicating their real functions during the T-cell differentation, have been, in fact, available. Here we report an update discussion concerning the possible role of the cooperation between TH and cytokines in T-cell development. Moreover we illustrate the results obtained by us and other authors, demonstrating a strict connection between the action of thymosins, a family of peptides first isolated and purified from calf thymus (1), and that of cytokines
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