1,029 research outputs found
[Paola Baroni Orsolini (1907), funerary sculpture]
From Berresford: Paola Baroni Orsolini (1907), Alfredo Angeloni, Cimitero Urbano, Lucca.Angel and woman.Title from Berresford
Safety of escitalopram in pregnancy: a case series
Cesario Bellantuono, Francesca Bozzi, Laura Orsolini Psychiatric Unit and DEGRA Center, United Hospital and Academic Department of Experimental and Clinical Medicine, Polytechnic University of Marche, Ancona, Italy Background: The aim of this paper is to report maternal and neonatal outcomes in pregnant women treated with escitalopram during pregnancy and breastfeeding. Methods: Women enrolled in the DEGRA Database at the Clinic of Affective Disorders in Pregnancy and Postpartum in Italy, treated during pregnancy with escitalopram and followed up throughout pregnancy, were included in this study. All patients provided written informed consent and the study was approved by the local ethics committee. Psychiatric diagnoses were assessed using the Structured Clinical Interview for DSM-IV (Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition) Axis I Disorders and symptoms were assessed using the Hamilton Rating Scale for Depression (17 items) and Hamilton Rating Scale for Anxiety (14 items). Clinical and sociodemographic characteristics as well as maternal and neonatal outcomes were recorded. Results: The case histories of seven pregnant women treated for depression and/or anxiety disorders with escitalopram were reported. Four women were also treated with benzodiazepines. All pregnancies were full-term and all newborns had normal Apgar scores. There were no major malformations or miscarriages following exposure to escitalopram. Mild withdrawal syndrome was reported only in a newborn who was also exposed to a benzodiazepine. Two infants exposed to escitalopram during breastfeeding did not show any health problems. Conclusion: Our experience with use of escitalopram in pregnant women did not reveal any maternal or neonatal concerns. However, considering the few cases analyzed and the paucity of published literature, no conclusions can be drawn on its safety profile in pregnancy and breastfeeding. Keywords: escitalopram, pregnancy, breastfeeding, major malformations, perinatal complication
Sviluppo semantico in età prescolare: il ruolo dell’interazione genitore-bambino.
INFAD Revista de
Psicologia. International Journal of Developmental and Educational Psycholog
Gabriella Ronzitti Orsolini, Il mito del Sette a Tebe nelle urne Volterrane
De Ruyt Franz. Gabriella Ronzitti Orsolini, Il mito del Sette a Tebe nelle urne Volterrane. In: L'antiquité classique, Tome 41, fasc. 2, 1972. pp. 768-769
SEGMENTAZIONE DI PAROLE: UN COMPITO PER VALUTARE LA FACILITÀ’ CON CUI I BAMBINI ANALIZZANO LE RAPPRESENTAZIONI FONOLOGICHE
TPL - Test di prima lettura per bambini di prima e seconda classe di scuola primaria
I test comunemente utilizzati per valutare le abilità di lettura si basano su dati quantitativi, relativi al numero di errori commessi e al tempo impiegato. Questi sono indici importantissimi, ma non considerano l’aspetto qualitativo del processo con cui i bambini riconoscono le parole che leggono.
La peculiarità e la novità del TPL stanno proprio nel fornire strumenti per analizzare qualitativamente lo sviluppo del processo di lettura, da una fase incentrata su una decifrazione frammentata della stringa ortografica fino a una pronuncia fluida e immediata della parola. Il TPL valuta lo sviluppo della lettura in bambini delle prime due classi di scuola primaria e si è rivelato utile per evidenziare diversi pattern di disturbo della lettura nei bambini dislessici
Ronzitti Orsolini (Gabriella). Il mito delle Sette a Tebe nelle urne volterrane
Hus Alain. Ronzitti Orsolini (Gabriella). Il mito delle Sette a Tebe nelle urne volterrane. In: Revue belge de philologie et d'histoire, tome 52, fasc. 1, 1974. Antiquité - Oudheid. pp. 179-180
BIOMARKERS LABORATORISTICI RELATIVI AL COINVOLGIMENTO OSSEO NELLE ARTROPATIE INFIAMMATORIE
Objectives: The purposes of the study are multiple: first to investigate the determinants of Dickkopf-1 (Dkk1) in ankylosing spondylitis (AS), second to understand the role of anti-citrullinated protein antibodies (ACPA) on systemic bone health and third investigate the effect in the short term of tumor necrosis factor α inhibitors (TNFI) on bone density, turnover markers and Wnt modulators in rheumatoid arthritis (RA).Methods. Three different groups were involved: biologic naïve AS, a large RA biologic naïve cohort for the ACPA part, and a subgroup of RA biologic naïve patients about to start TNFI due to disease activity. All patients must not have serious comorbidity and taking bone targeting drugs. According to the part patients underwent blood sample for serum variables, bone density and clinimetric evaluation. Treatment and demographic data were also collected.Results: In the first part we found that one of the determinants of Dkk1 in AS in parathyroid hormone (PTH) and this is truer in patients with longer disease duration. In the second part ACPA turned out to negatively affect systemic cortical bone in a titer dependent manner. Third we reported an increase in bone turnover after TNFI, together with an increase also in PTH hormone, a decrease in Dkk1 and a slight decrease in femoral bone mineral density (BMD). Dkk1 also in the third part showed a correlation with PTH.Conclusions: Despite differences among inflammatory arthropathies bone and immune system are tightly connected and influencing each other. Wnt system, PTH, ACPA seems to be some of the key actors of this connection and also therapies, like TNFI, can influence their balance. Those evidences underline once again the importance of integrating bone in the evaluation of patients and in the development of new treatment of new way of using the existing ones
Novel Psychoactive Substances (NPS) and Recent Scenarios: Epidemiological, Anthropological and Clinical Pharmacological Issues
This chapter considers the emerging issues and challenges faced by those trying to make sense of the ever-changing scene of Novel Psychoactive Substances (NPS). A range of inter-connected aspects require investigation and continual monitoring to achieve this goal. Here the focus is on epidemiological, anthropological and clinical pharmacological issues. Whilst such aspects are more relevant to understanding the NPS phenomenon, practical issues associated with doing so need to be appreciated. Those generating or using information on NPS need to comprehend what data are available, their limitations and uses. In that way, objective information can be fed into decision- and policy-making in relevant disciplines and arenas. A multi-disciplinary approach is advocated for understanding NPS. This chapter demonstrates how such inputs can be brought together and integrated successfully. Traditional investigatory approaches have a role to play, but the development of new and innovative techniques can complement them. Timely design and evolution of both epidemiological and scientific knowledge-bases can assist in casting new light on NPS, using a spectrum of lenses through which to view them
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