2,661 research outputs found
On the phenomenology of a two-Higgs-doublet model with maximal CP symmetry at the LHC: Synopsis and addendum
No full textManiatis M, Nachtmann O, Manteuffel von A. On the phenomenology of a two-Higgs-doublet model with maximal CP symmetry at the LHC: Synopsis and addendum. 2010
A metric linkage disequilibrium map of a human chromosome
No full textWe used LDMAP (Maniatis et al. 2002) to analyse SNP data spanning chromosome 22 (Dawson et al. 2002), to obtain a whole-chromosome metric LD map. The LD map, with map distances analogous to the centiMorgan scale of linkage maps, identifies regions of high LD as plateaus ('blocks') and characterises steps which define the relationship between these regions. From this map we estimate that block regions comprise between 32% and 55% of the euchromatic portion of chromosome 22 and that increasing marker density within steps may increase block coverage. Steps are regions of low LD which correspond to areas of variable recombination intensity. The intensity of recombination is related to the height of the step and thus intense recombination hot-spots can be distinguished from more randomly distributed historical events. The LD maps are more closely related to the high-resolution linkage map (Kong et al. 2002) than average measures of ? with recombination accounting for between 34% and 52% of the variance in patterns of LD (r = 0.58 – 0.71, p = 0.0001). Step regions are closely correlated with a range of sequence motifs including GT/CA repeats. The LD map identifies holes in which greater marker density is required and defines the optimal SNP spacing for positional cloning, which suggests that some multiple of around 50,000 SNPs will be required to efficiently screen Caucasian genomes. Further analyses which investigate selection of informative SNPs and the effect of SNP allele frequency and marker density will refine this estimate
CP violation in the general two-Higgs-doublet model: A Geometric view
No full textManiatis M, Manteuffel von A, Nachtmann O. CP violation in the general two-Higgs-doublet model: A Geometric view. Eur.Phys.J. 2008;57(4):719-738
Whither European Trade Mark Law? Arsenal and Davidoff: The Creative Disorder Stage
No full textProfessor Maniatis focuses on recent case law of the European Court of Justice (ECJ) to illustrate the present disorderly state of European trade mark law. With the advent of the Community Trade Mark within the European Union, the ECJ is in the process of shaping a new body of trade mark precedent that will influence both national registration laws and future legislative developments in trade mark and unfair competition law. The author proposes that this new course should be guided by basic principles of trade mark law rather than by compromise between adverse historical and national systems. The Article gives a history of the legislative framework behind the Community Trade Mark to set up a discussion of the ECJ\u27s jurisprudence on trade mark law. Maniatis analyzes judicial treatment of relevant doctrines, including distinctiveness, graphic representation, functionality, likelihood of association, and mark reputation
Testing coupling relations in SUSY QCD at a linear collider
No full textBrandenburg A, Maniatis M, Weber MM. Testing coupling relations in SUSY QCD at a linear collider. Presented at the SPIRES Conference C02/06/17
SCRaPL: A Bayesian hierarchical framework for detecting technical associates in single cell multiomics data
No full textSingle-cell multi-omics assays offer unprecedented opportunities to explore epigenetic regulation at cellular level. However, high levels of technical noise and data sparsity frequently lead to a lack of statistical power in correlative analyses, identifying very few, if any, significant associations between different molecular layers. Here we propose SCRaPL, a novel computational tool that increases power by carefully modelling noise in the experimental systems. We show on real and simulated multi-omics single-cell data sets that SCRaPL achieves higher sensitivity and better robustness in identifying correlations, while maintaining a similar level of false positives as standard analyses based on Pearson and Spearman correlation
A New type of CP symmetry, family replication and fermion mass hierarchies
No full textManiatis M, Manteuffel von A, Nachtmann O. A New type of CP symmetry, family replication and fermion mass hierarchies. Eur.Phys.J. 2008;57(4):739-762
On the phenomenology of a two-Higgs-doublet model with maximal CP symmetry at the LHC
No full textManiatis M, Nachtmann O. On the phenomenology of a two-Higgs-doublet model with maximal CP symmetry at the LHC. JHEP. 2009;2009(05):028
Identification de marbres antiques à Delphes
No full textDéroche Vincent, Mandi V, Maniatis Yannis, Nikolaou A. Identification de marbres antiques à Delphes. In: Bulletin de correspondance hellénique. Volume 113, livraison 1, 1989. pp. 403-416
SUSY QCD corrections to the polarization and spin correlations of top quarks produced in e(+)e(-) collisions
No full textBrandenburg A, Maniatis M. SUSY QCD corrections to the polarization and spin correlations of top quarks produced in e(+)e(-) collisions. Physics Letters B. 2003;558(1-2):79-91.We compute the supersymmetric QCD corrections to the polarization and the spin correlations of top quarks produced above threshold in e(+) e(-) collisions, taking into account arbitrary longitudinal polarization of the initial beams. (C) 2003 Published by Elsevier Science B.V
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