1,720,985 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Involvement of nutrient composition and intestinal flora on regulation factors of pharmacokinetics
Full text link腸内細菌叢の有無は、薬物の体内動態に影響を与えることが知られているが、日常生活に伴う腸内細菌叢の変動が薬の効果・副作用に与える影響は報告されていない。
そこで、食物繊維や整腸剤によりいわゆる善玉菌を増加させたモデルを作成し検討した。その結果、水溶性食物繊維投与により、善玉の腸内細菌が増殖し、肝臓において一部の代謝酵素の遺伝子発現が減少したものの、その影響は小さいものと示唆された。また整腸剤により同様に善玉の腸内細菌叢の増加が認められたが、薬物動態に与える影響は認められなかった。
以上より日常生活での食事や整腸剤投与に伴う腸内細菌叢の変動は、薬物の体内動態に大幅な影響を与えないことが示唆された。Absence of intestinal flora Affect pharmacokinetics of drug, however there was no report whether regulation of intestinal flora by daily life affect drug safe and effective.
This study investigated the effects of increment of good bacteria in intestine using the animal model treated dietary fiber and medicine for intestinal disorders. The results showed that water soluble dietary fiber and medicine for intestinal disorders, which increase good bacteria, did not significantly affect pharmacokinetics factors. This study suggested that regulation of intestinal flora in dairy life would not affect pharmacokinetics of drugs.研究課題/領域番号:15K18918, 研究期間(年度):2015-04-01 – 2017-03-31出典：「薬物動態変動要因としての栄養組成および腸内細菌叢環境の関与」研究成果報告書 課題番号15K18918
（KAKEN：科学研究費助成事業データベース（国立情報学研究所））
（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-15K18918/15K18918seika/）を加工して作成research repor
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Preventive effect of Kaempferia parviflora on metabolic Disease
Full text linkKaempferia parviflora(KP)は自然発症肥満2型糖尿病モデル動物において抗肥満効果やインスリン抵抗性改善を始め種々の代謝性疾患に対して改善効果を示した。また、KPに含まれるポリメトキシフラボノイドは脂肪細胞の分化誘導効果を示したことから、KPは脂肪に直接作用しインスリン抵抗性を改善したことが示唆された。以上のことからKPは代謝性疾患に対する特定保健用食品や医薬品のシードとして有用であることが示された。Kaempferia parviflora (KP), a Zingiberaceae plant, showed the preventive effects on metabolic diseases, including anti-obesity and improvement of insulin-resistance in spontaneously obese type II diabetic mice. Polymethoxylflavones, included in KP, enhanced the differentiation of adipocytes in vitro, suggesting that KP directly affected to adipocytes and improved insulin-resistance. In is concluded that KP is promising as a seed compound for developing therapeutic medicines or food for specified health use (FOSHU) for metabolic diseases.研究課題/領域番号:21790634, 研究期間(年度):2009 – 2010出典：研究課題「Kaempferia parvifloraの代謝疾患予防効果および作用機序の解明」課題番号21790634
（KAKEN：科学研究費助成事業データベース（国立情報学研究所））
（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-21790634/21790634seika/）を加工して作成research repor
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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