1,722,742 research outputs found
Synthesis of Enantiopure Termini-Differentiated Heptane Stereotriads. Application to Side Chain-Functionalized Tetrahydrofurans of IKD-8344
No full textEnantiopure epoxy cycloheptenyl sulfones syn-7b and anti-7b are prepared in five high-yielding and stereospecific operations from 1,3-cycloheptadiene. These substrates serve as effective precursors for cis- and trans-substituted tetrahydrofurans (12, 10) which are segments
of the antineoplastic agent IKD-8344
Synthesis of Enantiopure Termini-Differentiated Heptane Stereotriads. Application to Side Chain-Functionalized Tetrahydrofurans of IKD-8344
No full textEnantiopure epoxy cycloheptenyl sulfones syn-7b and anti-7b are prepared in five high-yielding and stereospecific operations from 1,3-cycloheptadiene. These substrates serve as effective precursors for cis- and trans-substituted tetrahydrofurans (12, 10) which are segments
of the antineoplastic agent IKD-8344
Total synthesis of IKD-8344
No full textComplete construction: The total synthesis of IKD-8344, a novel 28-membered ring macrodiolide antibiotic (see structure), was accomplished by employing Williamson ether synthesis, ??-alkoxymethacrylate radical cyclization, and Yamaguchi lactonization reactions. This synthesis is another example of the application of ??-alkoxymethacrylate radical cyclization reactions for the stereoselective construction of complex oxacyclic natural products.clos
[The Texas Co., Engine Drawing Card, Sketch No. 8344]
No full textThis engine drawing card was created for Texas Company, Class 4-24-C-. Section J-4-C. Sketch 8344. Copy Spec. 36-D-86
Linked collectors and determiners for: NEON Biorepository Carabid Collection (Trap Sorting).
No full textNatural history specimen data linked to collectors and determiners held within, "NEON Biorepository Carabid Collection (Trap Sorting)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/2564e9e2-0248-4a3b-8344-24fc0956ed73">https://bionomia.net/dataset/2564e9e2-0248-4a3b-8344-24fc0956ed73</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/2564e9e2-0248-4a3b-8344-24fc0956ed73">https://gbif.org/dataset/2564e9e2-0248-4a3b-8344-24fc0956ed73</a>. Formatted as a Frictionless Data package
Linked collectors and determiners for: Type catalogue of Terebridae (Mollusca, Gastropoda, Conoidea) in the Natural History Museum, London, U. K..
No full textNatural history specimen data linked to collectors and determiners held within, "Type catalogue of Terebridae (Mollusca, Gastropoda, Conoidea) in the Natural History Museum, London, U. K.". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/f43b0f7c-f6bc-4625-8344-0d79d6b3055d">https://bionomia.net/dataset/f43b0f7c-f6bc-4625-8344-0d79d6b3055d</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/f43b0f7c-f6bc-4625-8344-0d79d6b3055d">https://gbif.org/dataset/f43b0f7c-f6bc-4625-8344-0d79d6b3055d</a>. Formatted as a Frictionless Data package
Stereoselective synthesis of (+)-IKD-8344
No full textTotal synthesis of IKD-8344 was accomplished via stepwise cyclodimerization of the monomeric seco acid under Yamaguchi conditions. In the synthesis of the monomeric seco acid, Wittig olefination reaction was employed for an efficient bond formation at C7-C8. The threo-trans oxolane unit for the rings a and c was prepared via intramolecular Williamson ether synthesis of the hydroxyl mesylate prepared via asymmetric aldol reaction. Radical cyclization of a beta-alkoxymethacrylate intermediate furnished the threo-cis oxolane unit for the b ring fragment. (C) 2007 Elsevier Ltd. All rights reservedope
Asymmetric approach toward the total synthesis of antibiotic IKD-8344
No full textAn asymmetric approach toward the total synthesis of antibiotic IKD-8344 via vinyl sulfone methodology is described herein. Four major projects are involved in this area: (1) Stereoselective epoxidation of dienyl sulfones; (2) SN2′ methylation of vinyl sulfones; (3) Oxidative cleavage of vinyl sulfones; (4) Efficient syntheses of sidechain-functionalized tetrahydrofurans
Get-it [Material gráfico]: sweet and juicy : E. Pons Valencia-España : R.E. 8344.
No full textTit. en la etiqueta: "E. Pons / Valencia - España / sweet and juicy R.E. 8344 / Get-it
Cranium of <i>Geosciurus princeps</i> (DNMNH-8344), with scale bar of 1 cm.
No full textCranium of Geosciurus princeps (DNMNH-8344), with scale bar of 1 cm.</p
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