1,725,837 research outputs found
Block Card 4617 Summit Street
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: M & B Tavern (Toledo, Ohio) | 20th Century Commercial Style | Shore Acres (Toledo, Ohio) | Point Place (Toledo, Ohio) | North Toledo Area (Toledo, Ohio) | 4617 Summit Street (Toledo, Ohio
Block Card 4617 Monac Drive
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Cape Cod Style | 4617 Monac Drive (Toledo, Ohio) | Dwelling | Greenbush Knolls Addition (Toledo, Ohio) | Trilby Area (Toledo, Ohio)
Block Card 4617 Oakridge Drive
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Cape Cod Style | Dwelling | 4617 Oakridge Drive (Toledo, Ohio) | Forest Grove Addition (Toledo, Ohio) | Trilby Area (Toledo, Ohio)) | West Toledo Area (Toledo, Ohio
Block Card 4617 Vermaas Avenue
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: dwelling | 4617 Vermaas Aveue (Toledo, Ohio) | Cape Cod style | North Toledo (Toledo, Ohio) | Willys Park area (Toledo, Ohio) | Alfred Bailey Addition (Toledo, Ohio
Block Card 4617 Harbord Drive
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | 4617 Harboro Drive (Toledo, Ohio) | Dwelling | Monroe Acres (Toledo, Ohio) | Franklin Park Area (Toledo, Ohio) | Trilby Area (Toledo, Ohio)
Block Card 4617 Harford Road
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Dwelling (Toledo, Ohio) | Colonial Revival Style | Homeville Subdivision (Toledo, Ohio) | Willys Park area (Toledo, Ohio) | West Toledo (Toledo, Ohio) | 4617 Harford Road (Toledo, Ohio
Global and regional emissions estimates for N<sub>2</sub>O
We present a comprehensive estimate of nitrous oxide (N2O) emissions using
observations and models from 1995 to 2008. High-frequency records of
tropospheric N2O are available from measurements at Cape Grim, Tasmania;
Cape Matatula, American Samoa; Ragged Point, Barbados; Mace Head, Ireland;
and at Trinidad Head, California using the Advanced Global Atmospheric Gases
Experiment (AGAGE) instrumentation and calibrations. The Global Monitoring
Division of the National Oceanic and Atmospheric Administration/Earth System
Research Laboratory (NOAA/ESRL) has also collected discrete air samples in
flasks and in situ measurements from remote sites across the globe and
analyzed them for a suite of species including N2O. In addition to these
major networks, we include in situ and aircraft measurements from the
National Institute of Environmental Studies (NIES) and flask measurements
from the Tohoku University and Commonwealth Scientific and
Industrial Research Organization (CSIRO) networks. All measurements show
increasing atmospheric mole fractions of N2O, with a varying growth rate
of 0.1–0.7% per year, resulting in a 7.4% increase in the background
atmospheric mole fraction between 1979 and 2011. Using existing emission
inventories as well as bottom-up process modeling results, we first create
globally gridded a priori N2O emissions over the 37 years since 1975. We
then use the three-dimensional chemical transport model, Model for Ozone and
Related Chemical Tracers version 4 (MOZART v4), and a Bayesian inverse method
to estimate global as well as regional annual emissions for five source
sectors from 13 regions in the world. This is the first time that all of
these measurements from multiple networks have been combined to determine
emissions. Our inversion indicates that global and regional N2O emissions
have an increasing trend between 1995 and 2008. Despite large uncertainties,
a significant increase is seen from the Asian agricultural sector in recent
years, most likely due to an increase in the use of nitrogenous fertilizers,
as has been suggested by previous studies
Abstract 4617: Association between DNA oxidative damage and radiotherapy-induced skin toxicities in breast cancer patients
Abstract Background: Breast cancer is the most frequently diagnosed cancer and the second leading cause of cancer-related death in the female population in the United States. Although radiotherapy (RT) has been shown to improve prognosis in breast cancer patients, RT may also lead to side effects that impact overall quality of life in some patients. The objective of this study was to investigate whether an oxidative damage biomarker, 8-hydroxy-2-deoxyguanosine (8-OHdG), is associated with RT-induced early adverse skin reactions (EASRs) in breast cancer patients. Methods: 8-OHdG data before (pre-RT) and after RT (post-RT) were obtained from 475 breast cancer patients. RT-induced EASRs were assessed using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (v3.0) scale. Univariate logistic regression analyses were conducted to evaluate associations between above-median 8-OHdG (> 85 ng/ml) and RT-induced grade 2+ EASRs. A propensity score (PS) was derived from a logistic regression model for predicting RT-induced EASRs on the basis of patient, tumor, and treatment characteristics. Then, the association between 8-OHdG and RT-induced EASRs was assessed in four risk groups defined by quartiles of PS. Results: Overall, 59% of patients developed RT-induced grade 2+ EASRs and 28% developed moist desquamation. There were no significant associations between RT-induced EASRs and high 8-OHdG levels at both pre-RT and post-RT. However, there was a significant association between patients in the 2nd quartile PS that had high post-RT 8-OHdG levels and grade 2+ EASRs (OR=2.51, 95%CI=1.17, 5.40, p=0.0183). Conclusions: The results from this study suggest that 8-OHdG is a potential biomarker for RT-induced EASRs in a breast cancer population with low to medium (2nd quartile) propensity for RT-induced EASRs. Citation Format: Moody M. Mihyu, Isildinha M. Reis, Cristiane Takita, Jean L. Wright, Eunkyung Lee, Omar L. Nelson, George R. Yang, Johnna L. Bakalar, Jennifer J. Hu. Association between DNA oxidative damage and radiotherapy-induced skin toxicities in breast cancer patients [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 4617
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