1,725,347 research outputs found
[Southern Pacific, No. 4328]
No full textNegative sleeve: [handwritten] 2031 Southern Pacific Engine 4328, straight stack, 4-8-2
S.L.C. - Second South Street P.41
No full textView looking west, Second (2nd) South Street, Salt Lake City, Utah. May 29, 1938. Salt Lake Tribune #4328
MiR-4328 inhibits proliferation, metastasis and induces apoptosis in keloid fibroblasts by targeting BCL2 expression
No full textKeloids are considered to be a type of benign tumor. MicroRNAs have been reported to be involved in the formation and growth of keloids. MicroRNA-4328 (miR-4328) was found to be abnormally expressed in keloids, while the role and the detailed molecular mechanism of miR-4328 in keloids remain unclear. The expression of miR-4328 and B-cell lymphoma 2 (BCL2) mRNA was detected by qRT-PCR. The proliferation, migration, invasion and apoptosis of keloid fibroblasts (KFs) was examined using Cell Counting Kit-8 assay, transwell assay or flow cytometry, respectively. Western blot was used to detect the level of proliferating cell nuclear antigen, cleaved-caspase 3, collagen I, collagen III and BCL2 protein. The interaction between miR-4328 and BCL2 was confirmed by luciferase reporter analyses. It was observed that miR-4328 was down-regulated in keloid tissues and fibroblasts, and miR-4328 restoration mediated the inhibition of proliferation, metastasis, collagen synthesis and the promotion of apoptosis in KFs. BCL2 was up-regulated in keloid tissues and fibroblasts, and BCL2 knockdown promoted the deterioration of KFs. In addition, BCL2 was confirmed to be a target of miR-4328, and the rescue experiment indicated that the inhibitory action of miR-4328 on keloid fibroblast progression was reversed by BCL2 overexpression. Thus, our results demonstrated that miR-4328 restrained the deterioration of KFs by targeting BCL2, which sheds new light on miR-4328 as a promising target for keloid development and therapeutic
Block Card 4328 Foxglove Road
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: garrison colonial | 4328 Foxglove Road (Toledo, Ohio) | Dwelling | Harvest Lane Home Sites (Toledo, Ohio) | Franklin Park Area (Toledo, Ohio) | Trilby Area (Toledo, Ohio)
[Veto of H. 4328, R-290]
No full textThis veto message from Governor Mark Sanford vetoes H. 4328, R-290, a bill that amends the Administrative Procedures Act's sections dealing with review of final decisions, including DHEC permitting decisions, by the administrative law court
Block Card 4328 East Way
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Dwelling (Toledo, Ohio) | Colonial Revival Style | Homeville Subdivision (Toledo, Ohio) | Willys Park area (Toledo, Ohio) | West Toledo (Toledo, Ohio) | 4328 East Way (Toledo, Ohio
Block Card 4328 Parrakeet Avenue
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: dwelling | 4328 Parrakeet Avenue (Toledo, Ohio) | Folk House Style | Craftsman Style | Elmwood Park (Toledo, Ohio) | Willys Park area (Toledo, Ohio) | West Toledo (Toledo, Ohio
Block Card 4328 Kingsbury Avenue
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: dwelling | 4328 Kingsbury Avneue (Toledo, Ohio) | Tudor Cottage style | Elmwood Park (Toledo, Ohio) | Willys Park area (Toledo, Ohio) | West Toledo (Toledo, Ohio
J0316+4328: A probable 'asymmetric double' lens
No full textWe report a probable gravitational lens J0316+4328, one of 19 candidate asymmetric double lenses (two images at a high flux density ratio) from CLASS. Observations with the Very Large Array (VLA), MERLIN and the Very Long Baseline Array (VLBA) imply that J0316+4328 is a lens with high confidence. It has two images separated by 0.40 arcsec, with 6-GHz flux densities of 62 mJy and 3.2 mJy. The flux density ratio of ~ 19 (constant over the frequency range 6-22 GHz) is the largest for any two-image gravitational lens. High-resolution optical imaging and deeper VLBI maps should confirm the lensing interpretation and provide inputs to detailed lens models. The unique configuration will give strong constraints on the lens galaxy's mass profile. © 2007 The Authors. Journal compilation © 2007 RAS
Block Card 4328 Rose Garden Drive
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: dwelling | 4328 Rose Garden Drive (Toledo, Ohio) | Hipped roof | Nopper Garden Estates Plat 4 | Franklin Park Area (Toledo, Ohio) | West Toledo (Toledo, Ohio) | Ranch house
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