1,724,926 research outputs found
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No full textDataset 2 linked to NP: The TP IPR Games Development for Education and Health. This Metadata for Games development, design for educational health game as per confidential files uploaded. This metadata supports product design for copyright and IPR purposes. This registration marks the recording of the concept as the licensing options only support this publicly available statement via metadata required for discovery purposes. The aim is to ensure any Recall type developments in the given discipline or any specific details from which an association could be made is progressed only through permissions of the author/designer contact
Vegetation and seed bank of an open-scrub bush restinga formation in the Southeastern coast of Brazil
No full textIntroduction: Restingas are coastal plain ecosystems located along Eastern Brazil, correspond-ing to about 5 000 km. The restinga vegetation is associated with the Atlantic rainforest biome and comprises four distinct main formation zones: coastal grasslands, shrublands, open-forests and marsh zones. Especially due to coastal urbanization, this is a threatened ecosystem that, through its different shrub formations, exhibits a unique mosaic as a result of the vegetation distribution in nuclei of different covering, physiognomy and floristic composition. Objective: We aimed to characterize the above and belowground composition of a conserved, non-flooded, open-scrub, nuclei (patches of bushes) formation of restinga in Linhares, ES, southeastern Brazil. Methods: The vegetation survey was conducted using the line intercept method. Diameter and height of the first six nuclei were measured in five transects separated by 50 m, totaling 30 nuclei up to 350 m away from the shore line. The phytosociology and Shannon Index of the aboveground vegetation community were calculated. In the same 30 nuclei, leaf litter and topsoil layer (15 x 15 x 10 cm) samples were collected to survey the viable seed bank, which was later placed in a greenhouse for germination and seedling identification. The Sørensen Similarity index (SSi) was used to compare the floristic composition between the leaf litter and topsoil layer seed banks. Nuclei volume and number of species were calculated as well. Results: In the aboveground vegeta-tion, 54 plant species belonging to 32 families were identified, totaling 1 098 individuals. The nuclei showed a diversity (H’) of 3.08 nats, and an average diameter of 11.5 m (s = 9.1), area of 526.4 m2 (s = 1 081.7), and height of 2.9 m (s = 1.1). Davilla flexuosa, followed by Smilax rufescens, presented the highest IVI (Importance Value Index). A total of 1 839 seedlings from 32 species and 19 families were identified in the seed bank. Enydra sessilis (Asteraceae) had the highest seed density (544), while the family with highest species richness was Cyperaceae. A low similarity between the vegetation surveyed and the seed bank composition was found (only 5 species in common, SSi = 0.10). Conclusions: The results indicate that a post-disturbance early community, established from the seed bank, would have a substantially different species composition, but with other potential species to restore vegetation over the long-term successio
Abstract 4196: Identification and investigation of ethnic specific gene expression differences in non-cancerous breast tissue
No full textAbstract
Disparities in breast cancer (BC) stage of presentation and survival are well documented in patients of different ethnicities. These differences are undoubtedly due to a combination of extrinsic and intrinsic factors. Our group is focused on the genetic contributions to these disparities. Recent observations by our group and others suggest not only the involvement of specific genes contributing to BC risk in African-American (AA) women, but that multiple distinct ethnic-specific gene expression patterns exist in both matched cancerous and normal breast tissue samples. We report the first results of a parallel study which is addressing an unanswered question: are there ethnic-specific differences in the transcriptome of normal breast tissue? We are completing gene expression profiling studies in normal breast FFPE samples from 25 AA and 25 Caucasian (Cauc) women with no history of breast cancer. Laser capture micro-dissection (LCM) is used to further identify and extract epithelial vs stromal cells from each FFPE slide for use in RNA expression profiling. RNA isolation and hybridization occurs in collaboration with Almac Diagnostics (Dx) using their proprietary Breast Cancer DSA array. Gene expression data analyses involves multiple statistical packages developed for DNA microarray studies, and is focusing on comparison of gene expression profiles across four study groups- AA vs Cauc samples and epithelial vs stroma cells. For baseline comparison, a subset of this study group (10 AA and 10 Cauc samples non-LCM dissected) has also been analyzed. Results from these non-LCM dissected samples displayed expression differences between AA and Cauc in 333 known genes. Applying the stringency criteria of a fold change of two or greater and a statistical p-value of 0.01, reduced the significant gene list to 61 genes. Initial pathway analyses indicate these genes are involved in cell adhesion, G-protein signaling, apoptosis and survival pathways, and cytoskeleton remodeling - all critical pathways for cell survival. These initial results are being validated in the LCM-dissected samples, and our latest results will be presented. Results from analyses of these normal samples will be compared to our previous results obtained in matched tumor-normal triple negative AA and Cauc breast cancer samples (as well as publicly available data sets). Combined analysis of tumor and normal breast expression (transcriptome) data will help to better understand the possible significance of gene expression differences in breast tissue between ethnic groups.
Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 4196. doi:1538-7445.AM2012-419
Vegetation and seed bank of an open-scrub bush restinga formation in the Southeastern coast of Brazil
No full textIntroduction: Restingas are coastal plain ecosystems located along Eastern Brazil, correspond-ing to about 5 000 km. The restinga vegetation is associated with the Atlantic rainforest biome and comprises four distinct main formation zones: coastal grasslands, shrublands, open-forests and marsh zones. Especially due to coastal urbanization, this is a threatened ecosystem that, through its different shrub formations, exhibits a unique mosaic as a result of the vegetation distribution in nuclei of different covering, physiognomy and floristic composition. Objective: We aimed to characterize the above and belowground composition of a conserved, non-flooded, open-scrub, nuclei (patches of bushes) formation of restinga in Linhares, ES, southeastern Brazil. Methods: The vegetation survey was conducted using the line intercept method. Diameter and height of the first six nuclei were measured in five transects separated by 50 m, totaling 30 nuclei up to 350 m away from the shore line. The phytosociology and Shannon Index of the aboveground vegetation community were calculated. In the same 30 nuclei, leaf litter and topsoil layer (15 x 15 x 10 cm) samples were collected to survey the viable seed bank, which was later placed in a greenhouse for germination and seedling identification. The Sørensen Similarity index (SSi) was used to compare the floristic composition between the leaf litter and topsoil layer seed banks. Nuclei volume and number of species were calculated as well. Results: In the aboveground vegeta-tion, 54 plant species belonging to 32 families were identified, totaling 1 098 individuals. The nuclei showed a diversity (H’) of 3.08 nats, and an average diameter of 11.5 m (s = 9.1), area of 526.4 m2 (s = 1 081.7), and height of 2.9 m (s = 1.1). Davilla flexuosa, followed by Smilax rufescens, presented the highest IVI (Importance Value Index). A total of 1 839 seedlings from 32 species and 19 families were identified in the seed bank. Enydra sessilis (Asteraceae) had the highest seed density (544), while the family with highest species richness was Cyperaceae. A low similarity between the vegetation surveyed and the seed bank composition was found (only 5 species in common, SSi = 0.10). Conclusions: The results indicate that a post-disturbance early community, established from the seed bank, would have a substantially different species composition, but with other potential species to restore vegetation over the long-term successio
Linked collectors and determiners for: New data on the genus Manota Williston (Diptera: Mycetophilidae) from Africa, with an updated key to the species.
No full textNatural history specimen data linked to collectors and determiners held within, "New data on the genus Manota Williston (Diptera: Mycetophilidae) from Africa, with an updated key to the species". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/9823b3d4-a8ba-4196-b924-02bf807b4d61">https://bionomia.net/dataset/9823b3d4-a8ba-4196-b924-02bf807b4d61</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/9823b3d4-a8ba-4196-b924-02bf807b4d61">https://gbif.org/dataset/9823b3d4-a8ba-4196-b924-02bf807b4d61</a>. Formatted as a Frictionless Data package
Linked collectors and determiners for: Dinoxyleborus Smith, a new genus of Neotropical xyleborine ambrosia beetle (Coleoptera, Curculionidae: Scolytinae).
No full textNatural history specimen data linked to collectors and determiners held within, "Dinoxyleborus Smith, a new genus of Neotropical xyleborine ambrosia beetle (Coleoptera, Curculionidae: Scolytinae)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/33d3c80d-ac66-4196-9653-cc74045cdae1">https://bionomia.net/dataset/33d3c80d-ac66-4196-9653-cc74045cdae1</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/33d3c80d-ac66-4196-9653-cc74045cdae1">https://gbif.org/dataset/33d3c80d-ac66-4196-9653-cc74045cdae1</a>. Formatted as a Frictionless Data package
Linked collectors and determiners for: Modelación de la distribución real y potencial de especies de dos géneros de Mimosoideae: Mimosa y Prosopis (Leguminosae) en México (Mimosa).
No full textNatural history specimen data linked to collectors and determiners held within, "Modelación de la distribución real y potencial de especies de dos géneros de Mimosoideae: Mimosa y Prosopis (Leguminosae) en México (Mimosa)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/7162b803-bde2-4196-9383-263ba6dc9ad3">https://bionomia.net/dataset/7162b803-bde2-4196-9383-263ba6dc9ad3</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/7162b803-bde2-4196-9383-263ba6dc9ad3">https://gbif.org/dataset/7162b803-bde2-4196-9383-263ba6dc9ad3</a>. Formatted as a Frictionless Data package
Linked collectors and determiners for: Modelación de la distribución real y potencial de especies de dos géneros de Mimosoideae: Mimosa y Prosopis (Leguminosae) en México (Mimosa).
No full textNatural history specimen data linked to collectors and determiners held within, "Modelación de la distribución real y potencial de especies de dos géneros de Mimosoideae: Mimosa y Prosopis (Leguminosae) en México (Mimosa)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/7162b803-bde2-4196-9383-263ba6dc9ad3">https://bionomia.net/dataset/7162b803-bde2-4196-9383-263ba6dc9ad3</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/7162b803-bde2-4196-9383-263ba6dc9ad3">https://gbif.org/dataset/7162b803-bde2-4196-9383-263ba6dc9ad3</a>. Formatted as a Frictionless Data package
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