1,725,737 research outputs found
Simulating the charged charmoniumlike structure Z c ( 4025 )
No full textInspired by the recent observation of the charged charmoniumlike structure , we explore the decay through the initial-single-pion-emission mechanism, where the interaction is studied by the ladder approximation, including the non-interacting case. Our calculation of the differential decay width for indicates that a charged enhancement structure around appears in the invariant mass spectrum for this process, which might correspond to the newly observed structure
Interpretation of Z c ( 4025 ) as the hidden charm tetraquark states via QCD Sum Rules
No full textBy using QCD Sum Rules, we found that the charged hidden charm tetraquark states with and , which are possible quantum numbers of the newly observed charmonium-like resonance , have masses of and . The contributions up to dimension eight in the operator product expansion were taken into account in the calculation. The tetraquark mass of state was consistent with the experimental data of , suggesting the state to possess the quantum number of . Extending to the b-quark sector, the corresponding tetraquark masses and were obtained, which values are testable in future B-factories
Abstract 4025: New candidate therapy for BAP1-mutant cancer identified using novel screen
No full textAbstract Inactivation of the oncogene BAP1 is associated with poor prognosis in many cancers, including uveal melanoma (UM). Therapies for mediating the detrimental effects of BAP1 mutations have yet to be developed. Previously, we found that BAP1 depletion in Xenopus causes a striking developmental phenotype and a global dysregulation of differentiation markers across the genetic landscape. This was caused by impaired promoter assembly at commitment genes, marked by decreased H3K27ac levels. Inhibition of HDAC4 protein rescues the affected BAP1-depleted phenotype and genetic regulations, further emphasizing the role of H3K27ac in BAP1 function. Pairing these findings with a lab-devised multitiered screening process, we identified an epigenetic compound that successfully reverses the detrimental effects of the BAP1 deficient phenotype back to phenotypically normal conditions. This multitiered screening process tests prospective compounds for the ability to mediate transcriptional aberrations caused by BAP1 loss in UM cells (phase 1), rescue the BAP1 loss phenotype in Xenopus (phase 2), and provide significant inhibition of UM tumor growth in a mouse model (phase 3). These findings reveal a new application for a promising epigenetic compound as a therapeutic and reversing agent for BAP1 mutant UM. Furthermore, our streamlined process for the testing of promising therapeutic agents can accelerate the testing of such agents and getting them to clinical trials in a timely manner. Citation Format: DAWN A. OWENS, Jeffim N. Kuznetsov, Andy Lopez, Stefan Kurtenbach, Daniel Bilbao, Evan R. Roberts, Claude-Henry Volmar, Claes R. Wahlestedt, Shaun P. Brothers, J. William Harbour. New candidate therapy for BAP1-mutant cancer identified using novel screen [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 4025
Block Card 4025 Indian Road
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: St. Ursula Academy (Toledo, Ohio) | Postmodern Style | Old Orchard Area (Toledo, Ohio) | 4025 Indian Road (Toledo, Ohio
D* (D)over-bar* molecule interpretation of Z(c)(4025)
No full textWe have used QCD sum rules to study the newly observed charged state Z(c)(4025) as a hidden-charm D*(D) over bar* molecular state with the quantum numbers I-G(J(P)) =1(+)(1(+)). Using a D*(D) over bar* molecular interpolating current, we have calculated the two-point correlation function and the spectral density up to dimension eight at leading order in alpha(s). The extracted mass is m(X) = (4.04 +/- 0.24) GeV. This result is compatible with the observed mass of Z(c)(4025) within the errors, which implies a possible molecule interpretation of this new resonance. We also predict the mass of the corresponding hidden-bottom B*(B) over bar* molecular state: m(Zb) = (9.98 +/- 0.21) GeV.Physics, Particles & FieldsSCI(E)[email protected]; [email protected]; [email protected]; [email protected]
Block Card 4025 Peak Avenue
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Dwelling | 4025 Peak Avenue (Toledo, Ohio) | Willys Park Area (Toledo, Ohio) | West Toledo Area (Toledo, Ohio) | Gable front houses | Folk House Styl
Z(c)(4025) as the hadronic molecule with hidden charm
No full textWe have studied the loosely bound D*(D) over bar* system. Our results indicate that the recently observed charged charmonium-like structure Z(c)(4025) can be an ideal D*(D) over bar* molecular state. We have also investigated its pionic, dipionic, and radiative decays. We stress that both the scalar isovector molecular partner Z(c0) and three isoscalar partners (Z) over tilde (c0,c1,c2) should also exist if Z(c)(4025) is a D*(D) over bar* molecular state in the framework of the one-pion-exchange model. Z(c0) can be searched for in the channel e(+)e(-) -> Y -> Z(c0)(4025)(pi pi)(P-wave) where Y can be Y(4260) or any other excited 1(--) charmonium or charmonium-like states such as Y(4360), Y(4660), etc. The isoscalar D*(D) over bar* molecular states (Z) over tilde (c0,c2) with 0(+)(0(++)) and 0(+)(2(++)) can be searched for in the three pion decay channel e(+)e(-) -> Y -> (Z) over tilde (c0,c2)(3 pi)(P-wave)(I=0). The isoscalar molecular state (Z) over tilde (c1) with 0(-)(1(+-)) can be searched for in the channel (Z) over tilde (c1)eta. Experimental discovery of these partner states will firmly establish the molecular picture.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000327092600003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Physics, Particles & FieldsSCI(E)19ARTICLE11null7
Observation of a neutral charmoniumlike state Zc (4025)0 in e+e- → (D∗ D ¯ ∗)0π0
No full textÇetin, Serkant Ali (Dogus Author)We report a study of the process e+e-→(D∗D¯∗)0π0 using e+e- collision data samples with integrated luminosities of 1092 pb-1 at s=4.23 GeV and 826 pb-1 at s=4.26 GeV collected with the BESIII detector at the BEPCII storage ring. We observe a new neutral structure near the (D∗D¯∗)0 mass threshold in the π0 recoil mass spectrum, which we denote as Zc(4025)0. Assuming a Breit-Wigner line shape, its pole mass and pole width are determined to be (4025.5-4.7+2.0±3.1) MeV/c2 and (23.0±6.0±1.0) MeV, respectively. The Born cross sections of e+e-→Zc(4025)0π0→(D∗D¯∗)0π0 are measured to be (61.6±8.2±9.0) pb at s=4.23 GeV and (43.4±8.0±5.4) pb at s=4.26 GeV. The first uncertainties are statistical and the second are systematic
Linked collectors and determiners for: Modelación de la distribución real y potencial de especies de dos géneros de Mimosoideae: Mimosa y Prosopis (Leguminosae) en México (Prosopis).
No full textNatural history specimen data linked to collectors and determiners held within, "Modelación de la distribución real y potencial de especies de dos géneros de Mimosoideae: Mimosa y Prosopis (Leguminosae) en México (Prosopis)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/2d21ceb2-e459-4025-a62f-6b65c494de47">https://bionomia.net/dataset/2d21ceb2-e459-4025-a62f-6b65c494de47</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/2d21ceb2-e459-4025-a62f-6b65c494de47">https://gbif.org/dataset/2d21ceb2-e459-4025-a62f-6b65c494de47</a>. Formatted as a Frictionless Data package
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