1,796,053 research outputs found
Expedition 361 summary
No full textInternational Ocean Discovery Program Expedition 361 drilled six sites on the southeast African margin (southwest Indian Ocean) and in the Indian-Atlantic Ocean gateway, from 30 January to 31 March 2016. In total, 5175 m of core was recovered, with an average recovery of 102%, during 29.7 days of on-site operations. The sites, situated in the Mozambique Channel at locations directly influenced by discharge from the Zambezi and Limpopo River catchments, the Natal Valley, the Agulhas Plateau, and Cape Basin, were targeted to reconstruct the history of the greater Agulhas Current system over the past ~5 My. The Agulhas Current is the strongest western boundary current in the Southern Hemisphere, transporting some 70 Sv of warm, saline surface water from the tropical Indian Ocean along the East African margin to the tip of Africa. Exchanges of heat and moisture with the atmosphere influence southern African climates, including individual weather systems such as extratropical cyclone formation in the region and rainfall patterns. Recent ocean model and paleoceanographic data further point at a potential role of the Agulhas Current in controlling the strength and mode of the Atlantic Meridional Overturning Circulation (AMOC) during the Late Pleistocene. Spillage of saline Agulhas water into the South Atlantic stimulates buoyancy anomalies that may influence basin-wide AMOC, with implications for convective activity in the North Atlantic and global climate change. The main objectives of the expedition were to establish the role of the Agulhas Current in climatic changes during the Pliocene–Pleistocene, specifically to document the dynamics of the Indian-Atlantic Ocean gateway circulation during this time, to examine the connection of the Agulhas leakage and AMOC, and to address the influence of the Agulhas Current on African terrestrial climates and coincidences with human evolution. Additionally, the expedition set out to fulfill the needs of Ancillary Project Letter number 845, consisting of high-resolution interstitial water sampling to help constrain the temperature and salinity profiles of the ocean during the Last Glacial Maximum.
The expedition made major strides toward fulfilling each of these objectives. The recovered sequences allowed generation of complete spliced stratigraphic sections that range from 0 to between ~0.13 and 7 Ma. This sediment will provide decadal- to millennial-scale climatic records that will allow answering the paleoceanographic and paleoclimatic questions set out in the drilling proposal
Relative abundance of potassium at IODP Site 361-U1475
No full textRelative abundance of potassium at IODP Site 361-U147
Participant 361 Community Conversations Film
No full textIn this short film, Participant 361 shares how their family felt lost when the COVID-19 pandemic began, and that it led to experiencing low resources. The participant shares that they encouraged their family to remain positive, and urges people to focus on the positives to help forge through their hardships. They recommend spending time outdoors as a safe and effective way to support mental health.New Jersey Department of Healt
MiR-361-5p promotes proliferation and inhibits apoptosis of fibroblast-like synoviocytes <i>via</i> targeting ZBTB10 in rheumatoid arthritis
No full textThis study is aimed to explore the key role of miR-361-5p in fibroblast-like synovial (FLS) cells of rheumatoid arthritis (RA) and explore the underlying mechanism. First, we performed RT-qPCR to evaluate the expression of miR-361-5p in both synovial tissues of RA patients and cultured RA-FLS cells. Then CCK-8 assay, EdU staining, Western blot, flow cytometry, and ELISA were conducted to estimate the influence of inhibiting miR-361-5p on RA-FLS cells. Moreover, we used bioinformatics analysis to predict the potential targets of miR-361-5p and perform a dual luciferase report assay for verification. Finally, rescue experiments were performed to prove the role of miR-361-5p/Zinc Finger And BTB Domain Containing 10 (ZBTB10) in the proliferation, cell cycle, and apoptosis of RA-FLS. We find that the expression of miR-361-5p is increased in both RA tissues and cultured RA-FLS cells. The inhibition of miR-361-5p can not only inhibit proliferation, arrest the cell cycle in G1/G0 phase, and increase apoptosis, but also reduce the inflammatory factors secreted by RA-FLS cells. In addition, ZBTB10 is a direct target for miR-361-5p, over-expression of ZBTB10 reverses the effect of miR-361-5p in RA-FLS. MiR-361-5p promotes the progression of rheumatoid arthritis by targeting ZBTB10.Key pointsThe influences of miR-361-5p on RA-FLS cells. The influences of miR-361-5p on RA-FLS cells.</p
Bulletin No. 361 - Usefullness of New Sheep-coat Materials
No full textBulletin No. 361 - Usefullness of New Sheep-coat Material
Investigation of coincident radio-frequency drive for nondestructive readout in thin-film memories.
No full textBibliography: p. 76-77.Title page reads: Final report ESL-FR-361.NASA Research Grant NSG-496. M.I.T. Project DSR 76152
Gemeindenachrichten Ottensheim 2013 / 361 (2013 / 361)
No full textGEMEINDENACHRICHTEN OTTENSHEIM 2013 / 361
Gemeindenachrichten Ottensheim (-)
Gemeindenachrichten Ottensheim 2013 / 361 (2013 / 361) ([1]
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